个体基因型

Methods The 9 STR loci (D11S2368, D12S391, D13S325, D18S1364, D22-GATA198B05, D6S1043, D2S1772, D7S3048, D8S1132) were amplified with STR_Typer_10_v1 kit for 1619 unrelated individuals of Han population in Southern China. The PCR products were analyzed with 3100 genetic analyzer and GeneMapper ID 3.1v software. The forensic efficiency parameters were calculated by PowerState V12. xls and the Hardy-Weinberg equilibrium was tested with Arlequin 3.11v software. The genetic polymorphism of 9 STR loci in Han population of Southern China was quite high.

用STRT_yper_10_v1荧光标记试剂盒，对1619例中国南方汉族无关个体的9个STR基因座(D11S2368， D12S391， D13S325 D18S1364， D22-GATA198B05， D6S1043， D2S1772， D7S3048， D8S1132)进行扩增，用AB公司3100遗传分析仪和GeneMapper 3.1v软件作STR分型，用PowerStateV12.xls分析软件进行等位基因频率和法医学常用参数统计分析，用Arlequin 3.11v软件包作Hardy-Weinberg equilibrium平衡检验。

Magna populations in edge and central region was studied. In 39 A. magna samples and five A. chukar outgroups, the entire mtDNA D loop was PCR amplified. The 456-457 nucleotides of the DNA D loop domain Ⅰ have been sequenced by dideoxy chain termination method. The 16 variable sites(3 5% of the entire sequence) defined 15 haplotypes.

本研究采用聚合酶链式反应和直接测序的方法获得了采自甘肃的大石鸡一个边缘种群和两个中心地理种群共39个个体的线粒体DNA控制区基因456～457个核苷酸的基因序列，16个变异位点(占整个序列的3.5%)有15个单倍型。

The proposed improved genetic algorithm can achieve global search with migration and keep the best individual with elitism operation.

具有迁移作用的改良型基因演算法不但可以做到全域搜寻，还可以精英主义的概念取得最佳的个体。

But, in the stillbirth case, the genetic test showed the genotype of the calf was a homozygote normal.

而一只难产而死的仔牛遗传检测的结果为不带此不良基因的正常型个体。

Genetic variation that alters the structure, configuration, or quantity of any of the proteins involved in any of these mechanisms may contribute to interindividual variation in drug response.

在这些机制中不可或缺的包含有某些特定蛋白的作用，个体间基因的差异会对这些蛋白的量、结构及构型等产生一定的影响，进而影响药物的疗效。

The result ofpairwise Fst and Neutrality tests revealed significant genetic differentiation amongfour populations,and evolution of mtDNA COI gene incompliance with the Neutralitytheory.The genetic distance was the biggest between HEB and JXL,and was thesmallest between SDT and JXL among the 4 populations.

遗传多样性研究采用了线粒体DNA COI基因序列、RAPD和PCR-RFLP三种分子标记研究大猿叶甲4个地理种群的遗传结构和群体遗传多样性。1、对长约335bp的mtDNA COI片段进行序列分析，在4个群体64个个体中，共发现37个单倍型，总变异位点35个，多态位点29个，含量(63.68％)大于含量(36.32％)。4个地理种群的核苷酸多样性指数分别为，0.082、0.035、0.099、0.186。

The recent increase in identified polygenic factors related to type 2 diabetes and our understanding of the pathogenesis of diabetes provide potential opportunities to individualize therapy.

新近对2型糖尿病相关多基因因素识别能力的增加，以及我们对糖尿病发病机理认识的提高，为潜在的个体化治疗提供了可能。

Methods: For 4 tetrameric STR loci (D5S818, D8S1179, D18S51and D21S11) genetic research, monoplex PCR methods were established to study the allele frequency and the applicability of forensic medicine.

应用聚合酶链反应，聚丙烯酰胺凝胶电泳及银染分型技术，对延边地区109名朝鲜族无关个体进行群体调查，获得四种基因座的群体遗传学资料。

Moreover, 13 ADHD specific haplotypes in contrast to worldwide population samples were identified by direct sequence of the exo 3 of DRD4 for 128 ADHD probands.

对DRD4基因外显子3和外显子4的序列测定表明在128个ADHD个体中发现了13个ADHD特有的单倍型序列。

Results PML RAR α fusion gene of 8 onsetting APL patients were all positive (4 first occurrence, 4 reoccurence);6 of 20 were positive in APL remission phase,in which proportion ratio of promyelocyte in bone marrow smear were all below 5%; a new t...

结果 ：发病期的 8例APL患者(初发 4例、复发 4例)PML RARα融合基因均阳性；缓解期APL患者的 2 0人次检查中 6人次阳性，而其骨髓涂片早幼粒细胞比率均小于 5 %；发现一种新的S型变异易位，并见L、S型同时存在于同一个体。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。