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It has been reported that the leaf and root extracts of Petasites hybridus relieve gastrointestinal pain, lung-disease such as asthma and cough, as well as spasms of the urogenital-tract, and even suppress the proliferation of human T24 bladder carcinoma cells. In 2000, S-petasin had been found to decrease the testosteron releasing by rat testicular interstitial cells.

此植物体及其萃取物应用在治疗使用上已约有两千年的历史,在1994年的研究中指出其粹取物对於人类膀胱癌细胞株(T24)具有抗增殖的效果,且於2000年,本实验室研究发现其粹取物-硫蜂斗菜素具有抑制大鼠间质细胞分泌睪固酮的效用,然而它对於人类前列腺癌细胞株是否也会造成毒杀效应,目前则尚未有文献探讨。

Neurotransmitters traverse the physical space between two neurons and bind to special protein receptors on the postsynaptic cell.

神经传感横贯两个神经细胞的物质空间,在突触后的细胞中绑定特殊的蛋白质受体。

TUNEL method was used to detected the apoptosis in the artery. Results:①The MSC cocultured with VSMC expressed smooth muscle a-actin, calponin and CD31, no cells positive for calponin and CD31 were detected in the control group; and a lot of filaments were observed in the co-cultured MSC by electron microscopy.②We gain dual-stable expression of AT2R gene medicated by doxycycline regulatable system of mesenchymal stem cells.

单独培养及VSMC条件培养液培养的MSC仅SM-α-actin表达阳性;(2)Dox-on系统由四个质粒组成:调节质粒pUHD17-1 hyg,荧光报告质粒pUHC 13-3,筛选质粒pSV2neo以及含目的基因AT2R的应答质粒pUHD10-3/AT2R,以上质粒经鉴定均与其背景资料相符合,可用于实现目的基因片段在靶细胞中可调控表达研究;(3)本实验通过连续两个回合的转染及抗生素压力筛选,经Dox诱导表达后获取出低背景、高诱导表达AT2R基因的克隆。

The images of the 8th week's SEM and histological section showed that more CPC resorbedin the CPC-BMP group than in the CPC group. Trabecular in the CPC-BMP group, without the view of bone degeneration of osteonecrosis and resorptive lacuna, were stronger than in the other two groups.

在CPC-BMP组的骨小梁粗大,未见到明显的骨吸收陷窝,而且也未观察到在其他两组中常见的骨陷窝内骨细胞消失、骨坏死等骨质退化表现。

Furthermore, the network was searched for interactions linking uncharacterized gene products and human disease proteins to regulatory cellular pathways. Two novel Axin-1 interactions were validated experimentally, characterizing ANP32A and CRMP1 as modulators of Wnt signaling.

作者们进一步分析了这个网络里面未知功能的蛋白和跟疾病相关蛋白与细胞调控通路的关系,发现了两个新的Axin-1相互作用并被实验证实,及ANP32A and CRMP1在Wnt信号通路里的调控作用。

The investigators collected unstimulated saliva from 32 patients with primary T1/T2 oral squamous cell carcinoma and from 32 normal subjects matched for age, gender, and smoking history. Using the saliva supernatant, they isolated RNA, performed two-round linear amplification with T7 RNA polymerase, and applied human genome U133A microarrays for profiling human salivary transcriptome.

研究人员收集32位原发性T1或是T2口腔扁平细胞恶性肿瘤患者、以及32位年龄、性别与吸菸史相符的正常受试者唾液;使用唾液离心后的上清液,他们分离出RNA,以T7 RNA聚合脢进行两个回合的线性放大作用,以及应用人类基因体U133A微阵列来分析人类唾液转录体。

Two types of pyrophosphatase are present in plant tissues: soluble one in cytoplasm and insoluble one on the vacuolar membrane.

植物组织中有两种类型的焦磷酸酶,一类是细胞质中可溶性的无机焦磷酸酶,另一类是与细胞液泡膜结合的不可溶性焦磷酸酶(vacuolar PPase,V-PPase)。

In eukaryotic cells, the fundamental unit of chromatin is nucleosome, which is composed of a histone octamer with two copies of H2A, H2B, H3 and H4 and 146 base pairs of DNA.

真核细胞中,核小体是染色质的基本单位,它由两个拷贝H2A、H2B、H3和H4所组成的核心组蛋白八聚体,及缠绕于其上的146bp DNA构成。

In this study, the DNA fragments coding for amino acids 133~158 of VP1and 20~34 of VP4protein of type Asial FMDV were chemically synthesized and ligated into a tandem repeat 133~158-20~34-133~158. The sequences of signal peptide of Igκ chain and Kozak were fused to the 5'end of this tandem sequence and synthetic oligodeoxynucleotide containing CpG-ISS was fused to downstream of terminal coden of this tandem sequence. And then this long fragment was cloned into the eukaryotic expression plasmid pHook-2, forming a new secreted expression plasmid, named pAS1-E.

在第二章证明了亚洲Ⅰ型口蹄疫病毒VP1蛋白中133~158位氨基酸残基确是一重要B细胞中和抗原表位的基础上,依据第一章获得的口蹄疫病毒亚洲Ⅰ型VP1 cDNA序列及已报道Asial VP4序列,采用真核偏爱密码子化学合成了VP1中编码133~158位氨基酸及VP4中编码20~34位氨基酸这两个抗原表位基因,将其组成133~158-20~34-133~158串联结构,在其5′端加上鼠Igκ链信号肽序列,在翻译调节区加上增强表达的Kozak序列,同时在133~158-20~34-133~158串联结构3'端终止密码子下游加上CpG免疫刺激序列,将这些片段连接后,克隆到真核表达载体pHook-2上,构建成功了DNA疫苗重组表达载体pAS1-E。

The postoperative course was complicated by two acute cellular rejection episodes that were successfully managed with corticosteroid boluses and the addition of corticosteroids to maintenance immunosuppression.

移植后并发两次急性细胞性排斥反应,经过大剂量激素的冲击治疗后排斥反应得以逆转,在其后的维持治疗中增加了激素的使用。

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We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称;三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起,称之为挽歌体诗人或者史诗诗人,他们被称为诗人,似乎只是因为遵守格律写作,而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。

This is not paper type of business,it's people business,with such huge money involved.

这不是纸上谈兵式的交易,这是人与人的业务,而且涉及金额巨大。