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I n this research apoptosis of keratinocyte induced by interferon-γ and anti-Fas monoclonal antibody, mimicking down stream in the cascade of the pathogenesis of eczematous dermatitis, was used as an in vitro experimental model to screen drugs which can inhibit cell apoptosis.

通过比较SRB和MTT两种检测方法选用更敏感、准确的SRB方法以及用流式细胞仪同步监测SRB检测结果,建立了用SRB初步筛选抗细胞凋亡药物的方法,从而为筛选湿疹性皮炎的治疗药物奠定了实验基础。

The study was carried out in two breeds of sheep, Indonesia Thin Tail and Merino, both infected with F. gigantica. Kinetic analysis of Fasciola gigantica specific antibody responses revealed that resistant ITT do not produce a parasite specific IgG2 response; whereas susceptible Merino sheep produce a high parasite specific IgG2 response.

以印尼短尾羊和美利奴细毛羊两种品系的绵羊为实验动物,研究动物感染巨片形吸虫后所产生的抗体依赖性细胞介导的细胞毒反应的免疫应答。

In the biological functionaddition, both biochanin A and hesperitin might inhibited the colony -formation forming ability of K562 cells through up-regulated Notch signaling. Besides,The treatment with biochanin A and hesperitin enhanced the erythroid-differentiation of K562 cells. It is important to investigate Tthe molecular mechanisms of biochanin A and hesperitin to regulate the endogenous CBF1-dependent Notch signaling will be further investigated.

在生物功能方面,biochanin A与hesperitin可能经由Notch讯息传导的活化,抑制了K562细胞群落的形成,除此之外,这两种药物均明显促进K562细胞往红血球分化。biochanin A与hesperitin对於CBF1所媒介之内生性Notch讯息传导的分子调控机制仍有许多问题尚未厘清,需要更多的实验与研究来讨论。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

Viral replication and microbial translocation from the gut to the blood during HIV infection lead to hyperimmune activation, which contributes to the decline in CD4+ T cell numbers during HIV infection. Programmed death-1 (PD-1) and interleukin-10 (IL-10) are both upregulated during HIV infection.

加拿大蒙特利尔大学和美国佛罗里达免疫和基因治疗研究所的科学家合作进行的研究发现,膜蛋白PD-1和细胞衍生因子IL-10这两种分子联手作用,影响了艾滋病病人体内的CD4T细胞发挥正常作用,从而导致患者免疫系统受损并加快了患者病情的发展。

Using count the leave.and flow cytometric to identifiy ploidy levels for the regenerated plants derived from antherculture in burley tobacco in this article,it shows that using count the chloroplast method could identify the ploidy levels simply and economic but it cannot identify the mixoploid accurately, so it easily lead to misidentify.

本文分别用气孔保卫细胞叶绿体计数和流式细胞仪两种方法来鉴定花药培养再生植株染色体的倍性,结果发现叶绿体计数法可以简单经济的检测烟草花药培养再生植株的染色体倍性,但它不能准确地鉴定出混倍体植株,易造成误判。

The expression of subunits α5,β1,β3 was detected in normal morulas and increased in blastocysts. The expression of subunit α1 was not detected in morulas or blastocysts, but detected only in outgrowing trophocytes. 3. Expression of integrin β3 in irradiated group embryos was weaker than that of normal group. There was no expression of integrin α1 both in morulas and blastocysts in irradiated group and no difference in the expression of subunits α5 and β1 between these two groups.

结果:1、超声波照射组胚胎贴附率、滋养细胞外延生长率均显著低于正常胚胎。2、正常胚胎桑椹胚期即有α5、β1、β3整合素表达,而无α1表达;囊胚期α5、β1、β3表达增强,仍无α1表达;α1只出现在外延生长的滋养细胞。3、超声波照射组胚胎β3整合素的表达明显弱于正常组,且未见α1表达;而α5、β1的表达两组间无差异。

Recombinant hANG had no effect on the expression of VEGF and bFGF in both SMCC-7221 cells and HUVEC cells, suggested that hANG exerted its antiangiogenic role not through the inhibition of the autosecretion and parasecretion of angiogenic stimulatory factors VEGF and bFGF.

重组人血管抑素对SMMC-7721肝癌细胞及HUVEC细胞中两种血管生长刺激因子VEGF和bFGF的表达没有影响,提示血管抑素对肿瘤血管生长的抑制作用不是通过抑制血管生长刺激因子的自分泌和旁分泌来实现的。

Higher degree of staining was observed in epithelial cells than in stroma. Both 5α-reductases were mainly localized in the cytoplasm, while in a number of cells they exhibited a nuclear and perinuclear distribution.

型及Ⅱ型还原酶在前列腺组织中并不存在所谓的特异性的细胞类型分布,两种酶在腺上皮细胞中的表达均强于间质,而且以胞浆的染色为主。

Methods Control the methanol feeding in growth phase of Hansenula polymorpha by online monitoring. In induction phase, the expression levels of HBsAg when the methanol feeding were controlled by DO-Stat/pH-Stat method and by offline gas chromatography, as well as those when only methanol was fed and glycerol and methanol were fed alternatively, were compared.

在细胞生长阶段采用DO/pH线测量的控制方法,使酵母细胞密度达到一个较高水平,诱导期比较DO-Stat/pH-Stat法和离线检测甲醇两种控制流加甲醇的方法,同时也比较用甘油和甲醇双碳源间断流加法与单纯流加甲醇法对目的蛋白表达的影响。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。