两细胞的

Deamidation of asparaginyl and glutaminyl residues have been proposed to serve as a molecular clock regulating biological events such as protein turnover, development, and cellular aging.

天冬醯胺和谷氨醯胺这两个氨基酸的去胺基化被认为是调控细胞反应的分子时钟，这些反应包括蛋白质的转换率，细胞发育和细胞老化等。

In the late proliferative and secretive phases, expression of ERα in stromal cells significantly decreased to the level observed in the desquamative phase Differently, no clear expression of ERβ was detected in stromal cells in the late proliferative phase. However, its expression appeared again in the secretive phase.

结果显示： 1ERα和ERβ在恒河猴子宫内膜的上皮细胞、基质细胞中均有表达，其表达水平在正常月经周期中发生周期性变化：上皮细胞中两种受体的表达水平从增殖期开始逐渐升高，到增殖晚期最高；分泌期开始下降，直到月经期的水平。

Studies were conducted on cultured normal and hyperfunctioning human thyroid cells in order to compare the effects of thyrotropinon the secretion of cAMP.

以bTSH刺激体外培养的正常和甲亢甲状腺细胞，通过测定细胞生成环磷腺苷的量，探讨bTSH对两种甲状腺细胞功能的影响。

The sex pheromone-producing gland of Ancylis.sativa Liu is amodified intersegmental membrane as a dorsal bag between eighth and ninthabdominal segments.

对枣粘虫雌蛾性信息素腺体的扫描和透射电镜观察表明，枣粘虫性信息素腺体是由第八、九腹节间的节间膜特化而成，是位于背部的一个囊状结构，它由两部分构成，前部的方形囊状体和后部的三角形囊状体，二者之间有一突起的脊；雌蛾静止时，腺体随第八和第九腹节一起嵌缩于第七腹节内，求偶时，腹部末端外伸，腺体细胞表皮外露，释放性信息素；腺体细胞呈方形，其表面覆盖几丁质表皮，表皮顶端无孔；细胞核很大，呈椭圆形，由双层核膜包被，位于细胞中下部，内有丰富的染色质；细胞质内有丰富的内质网，其内还有大量的大小不等的脂肪滴，以及线粒体和溶酶体等细胞器。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

Methods: To prepare serum containing drugs with Marsdenia Tenacissima extracts using method A and B, and evaluate this effect via different concentration levels through cellular morphology and MTT. Results: The maximum of no toxicity concentration of Marsdenia Tenacissima extract A towards HepG2 was approximately 0.648mg/mL.

用两种方法制备乌骨藤提取物含药血清，采用不同浓度的含药血清分别作用于培养的HepG2细胞通过细胞形态学和MTT法检测乌骨藤提取物含药血清对HepG2细胞增殖的影响。

RESULTS: On the basis of either flow-cytometric or molecular analysis, 44 of 45 patients with CLL (98%; 95% confidence interval , 88 to 100) had a prediagnostic B-cell clone; in 41 patients (91%; 95% CI, 79 to 98), the presence of the B-cell clone was confirmed by both methods. The presence of immunoglobulin heavy-chain variable genes was determined in 35 of 45 prediagnostic clones (78%).

结果：在流式细胞或分子分析的基础上， 45名白血病患者有44例（98 ％； 95 ％可信区间，88～100 ）具有诊断前B细胞克隆；在41例（ 91％； 95 ％可信区间， 79～98 ），B细胞克隆的存在得到了这两种方法的证实。45个诊断前克隆中有35个(78%)具有免疫球蛋白重链可变基因。

One of these factors encases the vegetative cells in a polymer capsule that inhibits ingestion by the immune system's macrophages and neutrophils—the scavenger cells that normally degrade disease-causing bacteria.

其中一个因子会把繁殖生长型细胞包在聚合物组成的荚膜里，以抑制巨噬细胞与嗜中性白血球的吞噬作用（上述这两种细胞是免疫系统的清道夫，可消灭致病细菌）。

Methods: NG108-15 cells were cultured in vitro at 37℃in a humidified atmospherecontaining 5％CO_2. Aβ_(25～35) fragment was dissolved with deionized distilledwater and aged for 4 days at 37℃. The cells were exposured to 5μmol/LAβ_(25～35) for 24h to establish the cell model. Twelve rabbits were divided intotwo groups at random, and garaged with MWD or physiological saline controlrespectively for 7 days to collect two kinds of cerebrospinal fluid, theyare CSF from rabbits treated with MWD and CSF from rabbits treated withphysiological saline.

NG108-15细胞在37℃、体积分数为5％的CO_2培养箱中培养，Aβ_(25～35)溶解于双蒸水中，置于37℃培养箱中老化4d，使其寡聚，毒性增强，细胞被置于浓度为5μmol／L的Aβ_(25～35)中作用24h，建立起AD细胞模型。12只清洁级大耳白家兔购于华中科技大学同济医学院动物中心，将其随机分成两组，分别给与等量的加味温胆汤和生理盐水灌胃7d，末次给药后1h内用水合氯醛将给药组白兔麻醉，1.2ml／kg，无菌条件下用7号注射针头从枕骨大孔处垂直进针，抽取清亮含药脑脊液。

Radioactivity of 〓Tc-MIBI incepted by A549DDP cells in controlling group, Rh2 group, DDP group and Rh2＋DDP group account for 0.94%, 1. 08%, 1. 13% and 2. 0% respectively of the total radioactivity. There was evident difference between the former three groups and Rh2＋DDP group P＜(0.05 . Radioactivity of 〓Tc-MIBI incepted by A549 cells was 2. 38% of the total radioactivity, obviously higher than that in controlling group (P ＜O. 05). conclusions: gensenoside Rh2 of no toxicity concentration can reverse resistance of lung adenocarcinoma A549DDP cells to cisplatin.

对照组的A549DDP细胞摄取〓Tc-MIBI的放射性活性与总放射性活性的百分比为0.94%为，Rh2组的A549DDP细胞摄取〓Tc-MIBI的放射性活性与总放射性活性的百分比为1.08%，DDP组的A549DDP细胞摄取〓Tc-MIBI的放射性活性与总放射性活性的百分比为1.13%，这两组分别与对照组比较无显著性差别（P＞0.05）；Rh2+DDP组的A549DDP细胞摄取。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。