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Methylation is negative correlation with genetic transcription , and the mechanism is probably as follows : directly interfere the combination of specific transcripton and recognition site of each promoter ; mediated transcription inhibition by change the construction of chromatin; induced gene silencing by combination of methylation site and transcription inhibition. P16 gene is also called multiple tumor supresser gene , which is the best easily to methylate in the anti-oncogenes. P16 gene locates in 9p21 of mankind-chromatosome , and it's total length is 8.5kb .

甲基化与基因转录呈负相关,其机制可能是[3]:直接干扰特异的转录子和各自启动子识别位点的结合;通过改变染色质结构,介导转录抑制;甲基化DNA位点直接与转录抑制子结合,诱导基因沉默。p16基因又称为多肿瘤抑制基因( multiple tumor suppressor 1 ,MTS1) [4] ,是肺癌中最易发生甲基化的抑癌基因,该基因位于人类染色体9p21上,全长8.5kb ,由两个内含子和三个外显子组成。

The next phase will be to be trial offer depending on the cost for two or three cycles to an individual so the key milady pregnancy rate can begin to be respectable numbers.

下一阶段的提供依赖于两个或三个周期的成本,这要针对个体,这样主要的怀孕率才能开始提高。

Any two of them are economically and militarily strong enough to prevent the third from dominating the region.

任何两个国家在经济上和军事上都足够强大到阻止第三个国家对这一地区的支配。

Anatomizes two reasons that Militarization of space will result in wars and three excuses that peace could exist .

从技术层面上宏观地剖析了外空军事化有可能导致战争的两个原因,阐明了和平的可能性存在的三个理由

Sell Mini Packages - Take two or three of the products and bundle them together to create smaller fast-moving packages.

出售迷你包-以两个或三个的产品和捆绑他们共同创造规模较小的快速移动的套餐。

Consist of a minimum of 3 point balanced illumination; two (2) points of illumination should be

照明布置图–被拍摄者照明的布置图包含至少三个平衡照明点;两个

He found that the interval of an octave is rooted in the ratio 2:1,that of the fifth in 32,that of the fourth in 4:3.and that of the whole tone in9:8.the phthagoreans applied these ratios to lengths of a string on an instrument called a canon,or monochord(a board with two bridges between which a string is stretched and a third bridge that divide the string in two parts);and thereby were able to determine mathematically the intonation of an entire musical system.

毕达哥拉斯将这些弦长比例应用于一种叫做卡农的乐器上,卡农也可以称之为单弦琴或者单弦音响测定器(是一个由两个码构成的木板,码子之间有一条被拉伸的琴弦,第三个码子位于琴弦两端的码子之间),因此能够用数学的方法测定整个音乐系统的音调。

This mulling machine has three support legs; two at the front and one at the rear.

本机有三个正在考虑支持腿,两个在前,一个在后面。

Two of the musketeers are called Athos and Porthos.What was the name of the third Musketeer?

其中两个剑客叫做阿托斯和波托斯,第三个剑客的名字叫什麼?

In Alexander Dumas'book,"The Three Musketeers", two of the musketeers are called Athos and Porthos. What was the name of the third Musketeer?

在亚历克斯大仲马的书中,其中两个火枪手叫做阿托斯和波托斯,第三个火枪手的名字叫什麼?

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。