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丝状伪足

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Moreover, we employ a maximum-likelihood-estimation algorithm to improve the lateral resolution of NIWOP images. The super-resolution NIWOP images are used for the analyses of filopodium dynamics of cancer cells.

我们并以最大可能估计演算法提升此光学技术的横向解析率,并将此明视野超解析率影像技术应用於癌细胞丝状伪足的动态分析上。

The results show that the hydrophilicity of PLA film is improved by introduction amido: the contact angle decreases from 78° to 56° and the free energy increases from 42.7mJ/m^2 to 51.4mJ/m^2. Compared with the control, osteoblast spread out more filopodia after 3 d incubation on amidation surface, and it entered cell division phase more quickly, which indicated that the surface amidation could promote the cell's adhesion and proliferation on the PLA film.

结果表明,酰胺基的引入改善了PLA膜的表面亲水性,其表面水接触角由78°减少到56°,自由能由42.7mJ/平方公尺增大到51.4mJ/平方公尺;与对照组相比,成骨细胞在改性表面培养3d后有大量的丝状伪足伸出,并且较快地进入了细胞分裂期,表明PLA膜表面的酰胺化能够促进细胞的黏附和增殖。

Results Under TEM, the surface and nuclear membrane split, a great number of vacuoles and high electron density particles appeared in the cytoplasm in Pc trophozoites, vacuoles also did in Pc cysts, intracystic bodies became denaturation and necrosis; under SEM, filopodia and microvilli became sparse,short and fell off, a breach appeared in the surface membrane in Pc trophozoites.

结果 透射电镜发现Pc滋养体表膜和核膜破裂,胞质中出现大量空泡和高电子密度颗粒,Pc包囊中也出现空泡,囊内小体变性坏死;扫描电镜发现Pc滋养体丝状伪足和微绒毛稀疏、变短甚至脱落,表膜出现缺损。

Moreover, we established the model of apoptosis induced by corticosterone and explored the effect of gangliosides, which is a active component in pilous antler, on this apoptotic cell model. The effects of gangliosides on neurotransmitter release, neuronal filopodia formation, calcium signal cascade and 5-HTl A receptor-ligand competitive binding were also studied. 2. Theory study: The viewpoint on brain and kidney in traditional Chinese medicine and that in Western medicine were comparatively studied. The essence of the relationship between kidney and brain in traditional Chinese medicine Subsequently, in combination with the analysis on the results in the empirical study, we discussed the essence of the relationship between kidney and brain in traditional Chinese medicine from the viewpoint about the feedback mechanism of hippocampus-hypothalamic-pituitary-adrenal.

体外实验采用糖皮质激素建立神经细胞凋亡模型,研究鹿茸有效成分的干预作用,并从神经递质释放、神经细胞丝状伪足生成、神经细胞钙信号途径、5-HT_(1A)受体配体竞争结合等方面进行机制探讨。2、理论研究:比较中西医学对肾和脑的传统认识以及现代研究,分析中医学中肾和脑的现代科学内涵,结合实验研究结果,从现代生物学海马—下丘脑—垂体—肾上腺轴负反馈机制的角度对中医肾脑相关理论的实质进行探讨。

These changes, which depend on transcription and translation, include formation of motile presynaptic filopodia, elaboration of undifferentiated varicosities, and potentiation of spontaneous release frequency.

这种依赖转录和翻译的变化包括动力型突触前丝状伪足的形成和未分化神经膨体的修饰,以及自发释放频率的增强等。

The number of filopodia and microspikes of HeLa-fascin cells was decreased and the cells grew together.

在HeLa细胞中,反义封闭fascinl基因后,细胞的丝状伪足和微棘减少,表现为聚集生长。

"Fascin is a key component of filopodia, and, inside the colorectal cancer cells, it represents the target of a circuitry that leads to the activation of several genes."

&Fascin是丝状伪足的关键成分,在肠癌细胞内部,是导致许多基因活化某回路的靶标。&

Iral expression of a mutant Rac1 decreased astrocyte motility and increased the length of dendritic filopodia but not their motility or lifetimes.

变异Rac1的病毒性表达降低星形胶质细胞的活动性,增长树突丝状伪足的长度但不增加其活动性和寿命。

The results demonstrated that (1)exogenous LN induced CCL229 cells to move by extending its filopodia andpromoted its motility,adhesion to HABM and invasion in vitro.

研究结果显示,外源性LN可诱发高侵袭力CCL229细胞产生带分枝的丝状伪足,而且对其移动性、对基底膜的粘附性和体外侵袭力均有明显促进作用。

The possible mechanism is that, when there is an asymmetry of RhoA activity in the growth cone, the filopodia at the lower RhoA activity side will extend faster then the other side because of lower inhibition or retraction, and hence the growth cone will turn towards this side.

可能的机制是,当生长锥内一侧的 RhoA 活性较另一侧高时,丝状伪足在 RhoA 活性低的一侧受到的抑制较弱,延伸更快,因此生长锥朝向该侧转向。

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