丙烯酰基

In chapter three, the activating agents of ytterbium have been examined. Barbier-type reaction promoted by ytterbium metal was examined. The experimental results shown that the yield of Barbier reaction of imines with allylic bromide promoted by ytterbium is higher than that of aldehydes and ketones with allylic bromide under the same reaction conditions. In this chapter, the reductive cleavage of Se-Se and S-S bond induced by ytterbium metal was also studied.

首先研究了金属镱的活化剂以及活化方法，接着考察了金属镱促进的Barbier反应及其在合成高烯丙基胺和高烯丙基醇中的应用，以及影响该反应的主要因素；究了金属镱促进的二硫醚和二硒醚的S—S键和Se—Se键的还原断裂，继而与氯代烃，胺基甲酰氯反应生成相应的硫醚，硒醚，胺基甲酸硫代酯和硒代酯。

Mainly engaged in: Hydrogen-imide hydrochloride, o-chlorophenyl cyclopentanone, 3.4 dimethoxy ethyl benzene, butyn single potassium acid, potassium ethyl malonyl, Ding amide, amide isobutyraldehyde , allyl chloroacetate, isopropyl chloroacetate Benzyl aluminum, cyclopentene, cyanide-o-chlorophenyl, o-methyl chloride, sulfuric acid chloride, p-chlorophenol, imidazole, Pinacolone, one chlorine Pinacolone.

主要经营：盐酸氢亚胺、邻氯苯基环戊酮、3.4二甲氧基苯乙酯、丁炔二酸单钾盐、丙二酸单乙酯钾盐、丁酰胺、异丁酰胺、氯乙酸烯丙酯、氯乙酸苄酯异丙醇铝、环戊烯、邻氯苯氰、邻氯苯甲酯氯、硫酸氯、对氯苯酚、咪唑、频呐酮、一氯频呐酮。

The auxiliary can be recovered in high yield (81%) only by filtering and recrystallization. Besides, some other aldehydes have been chosen to test the enantioselectivity of N,N\'-dibenzyl tartamide, in comparison with two other allylaborates reagents developed previously by Roush and Brown, respectively. The results show that %e.e. of homoallylic alcohol is superior to that of the former, and approaches the Brown reagent.

产物经S_N2反应得瑞格列萘中间体-甲基烯丙基-2-氯苯基-叠氮甲烷(17)；同时，将筛选出的新型手性配体N-苄基酒石酸二酰胺用于其他几种醛(正丁醛，异戊醛和环己醛)的不对称烯丙基化反应，并与广泛应用的Roush配体(22)和Brown配体(27)相比较，发现其立体选择性优于Roush配体，并接近Brown配体，但明显具有可回收利用的优势。

Chiral compounds Ⅰ for the first time was applied to allylation of acylhydrazones with allyltrichlorosilane and the results showed that the compound Ⅰ can contribute to the occurrence of the reaction.

首次将手性化合物Ⅰ应用于烯丙基三氯硅烷和酰腙的烯丙基化加成反应中，结果表明化合物Ⅰ能够促进该反应的发生。

A novel liquid crystalline compound named p-phenylenediamine di 4-[2- benzamide] was synthesized from allyl 2-hydroxyethylether, ethyl 4-hydroxybenzoate and p-phenylenediamine.

以乙二醇单烯丙基醚、对羟基苯甲酸乙酯、对苯二胺为原料合成了末端为不饱和双键的芳香聚酰胺溶致型液晶化合物——二对烯丙氧基乙氧基苯甲酰对苯二胺，最佳合成的摩尔比为∶羧酸∶对苯二胺∶吡啶=2。

A process for the carbonylation of allylic butenyl ether (for example, methyl crotyl ether, 3-methoxybutene-1 and mixtures thereof) or mixture of butadiene and alcohol and production of beta-gamma unsaturated carboxylic acid esters (for example, methyl-3-pentenoate) utilizing a rhodium-containing catalyst for example, dicarbonylacetylacetonate rhodium(I or the like promoted with an iodide-containing compound (for example, HI, AlI3, SnI4, TiI4, CrI3, and CoI2 or the like).

一种将烯丙型丁烯基醚(如甲基巴豆基醚、3－甲氧基丁烯－1及其混合物)或者丁二烯与醇的混合物羰基化的方法，以及由含碘化物化合物(如HI、AlI3、SnI4、TiI4、CrI3和CoI2或等效物)促进，用含铑催化剂如二羰基乙酰丙酮酸铑(I或其等效物制备β－γ不饱和羧酸酯(如甲基－3－戊烯酸酯)的方法。

The third part of this thesis is reactive simulating calculation In this section, some well-known auxiliaries are selected to compute in density functional theory B3LYP on Gaussian 03, from which the relationship between reaction active energies of transition states and enantiomeric excess of chiral products homoallylic alcohols isobtained based on relative reactive ratio theory. Using this relationship, calculations on the reaction of more than eight auxiliaries with four other aldehydes are carried out in AMI and MNDO, proving that N,N\'-dibenzyl tartamide has higher enantioselectivity than others in this reaction.

第三部分为计算化学部分，运用密度泛函理论B3LYP方法在Gaussian03软件上对已经报道的几种手性配体参与的醛不对称烯丙基化反应过程进行模拟计算，基于相对反应速率理论找出两种构型过渡态间活化能的差异与产物光学收率之间的关系；并以此为基础，用AM1和MNDO方法对上述合成的几种配体控制的反应过程进行量化计算，从而在理论上证实了N-苄基酒石酸二酰胺配体在醛的不对称烯丙基化反应中具有较高的立体选择性。

In a similar way, using N,N\'-dibenzyl tartamide as auxiliary,-(2-methyl)allyl-2-chloro-phenyl-methyl azide, a vital intermediate of Repaglinide, can be prepared via asymmetric allylation of o-chlorobenzaldehyde in

产物经氧化和碘加成内酯化反应得到阿伐他汀中间体(3R，5S)-3-羟基-5-碘甲基戊内酯(10)；将N-苄基酒石酸二酰胺用于邻氯苯甲醛的不对称烯丙基化反应以较高光学收率得-甲基烯丙基-2-氯苯基-甲基醇

It is found that the stereochemistry of the reactions of telluronium allylide,crotonylide and trimethylsilyallylide with α,β-unsaturated esters and amides can be tuned by thechoice of reaction conditions.

利用反应条件的变化首次实现了烯丙基、巴豆基、含硅烯丙基碲叶立德与α，β-不饱和酯、酰胺进行环丙烷反应的立体化学调控，能高立体选择性地、高效率地合成两种不同几何异构体中的一个。

Allyl-functional novolac with allylation degree of 173 % was synthesized , followed by copolymerizing with 4 , 42bismaleimide biphenyl methane at a mass ratio of 1∶1 to obtain BMI2modified allyl-functional novolac (BMAN173) resin.

制备了烯丙基化程度可达 173 %的烯丙基酚醛树脂(AN173)，并与双马来酰亚胺以 1 ∶1 的质量比进行共聚，制备了双马改性的烯丙基酚醛树脂(BMAN173)。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新