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A significant negative linear correlation between clonidine concentration and rCBF or spindle activity was observed in the thalamus, prefrontal, orbital and parietal association cortex, posterior cingulate cortex, and precuneus.

统计学分析后,发现在丘脑区、前额叶、眶上回及顶叶联合脑区大脑皮质、背扣带回大脑皮质、楔前叶,可乐定浓度与区域脑血流( rCBF ,即脑电图出现梭形波)呈统计学意义的负线性相关关系。

It may be relayed through the dorsal columns of the spinal cord in addition to the spinothalamic tract.

它也可通过脊髓的背侧神经束和脊髓丘脑束中继传递。

The latest work, in primates, found that scratching the skin blocks activity of nerve cells in the spinothalamic tract during itchiness - preventing the spinal cord from transmitting signals from the scratched area of skin to the brain.

对灵长类动物最新研究发现挠皮肤阻碍了在出现痒感觉期间脊椎丘脑路径上的神经细胞活动--从而防止了脊髓把那个被挠皮肤区域发送信号给大脑。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

It is revealed that the rapid adaptation also occurs subcortically and is also frequency-dependent.

结果表明,丘脑神经元也存在一定程度的快速适应,而且也具有频率依赖性。

Objective To identify the mechanisms of the subthalamic nuclei high frequency stimulation for Parkinson's disease.

目的 研究丘脑底核高频电刺激对大鼠黑质-纹状体系统的影响。

There is a part of the brain called the subthalamic nucleus.

大脑中有种叫作丘脑下神经核的,科学家们称它不仅对控制运动而且还对控制冲动行为有重要作用。

Objective To describe the technical approach and to assess the efficacy and safety of deep brain stimulation of the subthalamic nucleus in Parkinson's disease.

目的 总结帕金森病脑深部刺激术治疗的手术方法和效果。方法对25例帕金森病患者进行了丘脑底核DBS治疗,其中单侧17例,双侧8例。

Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis.

丘脑下核深部脑刺激治疗帕金森的认知后遗症:一项meta分析

Stereotactic techniques were used to implant one co-axis electrode in each subthalamic nucleus.

各组大鼠均利用立体定向的方法在双侧丘脑底核植入同轴电极。

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