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At first, this paper makes a systematic exposition of the content of supply-chain, supply-chain-management, purchasing in supply chain and purchasing management in supply chain environment and builds the theoretical foundation of this paper. Then, Make out the material classification from the acquirability of supply market and essentiality of material. Then based on this conclusion bring forward the proper purchasing strategies for Wuxi Weifu Group Co., Ltd. such as win-win strategy, ensure supply strategy, minimize cost strategy and minimize managerial cost strategy. Then sets up evaluated indexes system of short-term-efficiency-suppliers and long-term-efficiency-suppliers, applying the Fuzzy-evaluation method to evaluate suppliers. At the end of this paper, taking Wuxi Weifu Group Co., Ltd. as a case, comparing the status of its purchasing and supplier management, it puts forward some improvement suggestions to the existing problems in light of the above analysis such as the establishment and improvement of management information system, reengineering of purchasing organization and process, establishment of evaluated indexes system and implement of Just-in-time purchase.
本文首先系统的阐述供应链及供应链管理,供应链管理下的采购和采购管理的内容,从而构筑了本文的理论基础;继而,从物料采购的市场可得性和物料的重要性两种维度将物料分为战略性物料、瓶颈物料、重要物料、一般物料,在此基础上结合无锡威孚公司产品提出了相应的双赢、保障供应、最低成本、管理成本最小等采购策略;接着,建立了短/长期效率型供应商综合评价的指标体系;运用模糊综合评判方法对供应商的选择与评价体系进行了研究;最后,以无锡威孚集团有限公司为案例进行研究,结合前述的理论框架,通过对其采购和供应商管理现状的比较分析,找出不足之处,提出了改进建议和设想,如管理信息系统的建立和完善、采购组织和流程的重构、供应商选择评价体系的建立、即时制采购的实施等方案。
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Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.
作为一个很有潜力的抗肿瘤物质,三羟异黄酮的作用机制主要包括:①抑制蛋白酪氨酸激酶活性,可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递,导致癌细胞增殖受抑;②弱雌激素作用:可通过与体内雌激素受体结合,并可增加细胞内性激素结合球蛋白的合成,增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性;③拓扑酶Ⅰ和Ⅱ抑制剂,抑制细胞活性;④上调细胞周期性负性调节因子P21WAF1/CIP1的表达,使之负性调节因子作用增强;⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长;⑥其他:抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。
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The structure reveals the catalytic intermediate of DAPDC, in which L-lysine is covalently bonded to PLP to form an external aldimine. This conformation provided the best insight to date on the substrate binding and catalytic mechanism of DAPDC. It also supplied valuable clues for designing specific DAPDC inhibitors.
通过分析我们发现这是DAPDC酶家族的第一个反应中间态结构,即反应产物L-赖氨酸与辅酶PLP共价结合形成了外源醛亚胺的构象,这为了解DADPC的底物结合情况及催化机理提供了迄今为止最详细深入的结构信息,也为针对DAPDC设计特异性抑制剂提供了宝贵的线索。
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Through a combination of T7 RNA polymerase and T7 Promoter for testing proper buffer was selected.The experimental results showed 5×binding-Buffer 1 was more suitable for the test;TBE running-buffer was better than TAE and TGE buffer;0.2×TBE buffer was the best concentration amang there electrophoresis buffer.
通过用T7RNA聚合酶与T7启动子DNA的结合反应来选择合适的缓冲液,结果表明,不同的缓冲液会影响凝胶迁移试验的结果,5×Buffer1结合缓冲液的效果较好;TBE电泳缓冲液比TAE、TGE的电泳效果好,同时在3种不同浓度的TBE缓冲液中,0.2×的TBE效果最好。
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In aqueous solution no binding observed in crystal structure. In cyclohexane, one amylamine molecule is observed in the active site of trypsin and more sulfates are also found on enzyme surface, which are further proofs that electrostatic interaction are stronger in organic solvent.
在水溶液中,晶体结构难以观察到戊胺与牛胰酶的结合,在环己烷中,一个戊胺分子结合在胰酶的活性中心,同样酶表面观察到了更多的硫酸根,这些都进一步验证了有机溶剂中静电相互作用加强。
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The angelic vibratory codes held within the Archangelic language will increasingly integrate with our own / consciousness forms as we prepare ourselves for the ascension, thus the sound of these vibratory patterns will be incorporated into the matrix of the body of creation.
包含在大天使风格编码里的天使振动编码日益与我们自己的遗传基因/意识体结合在一块,如同我们在做升天的准备一样,这样这些振动模式的声音就会结合在一起进入创造物身体内的能量矩阵里面去。
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The results demonstrate that SarA regulated directly the expressions of lipA, zinC and atlE by protein-DNA binding to the promoter region of AT-rich sequence.
生物信息学分析表明,SarA控制atlE,lipA和zinC 3种基因表达可能是通过与被调控基因上游的特定DNA序列的结合来实现的,该DNA结合区保守并富含AT碱基。
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Ecological environment factors affecting its growth and development and the spatial distribution characteristics of plant autoeciousness of Hemiberlesia pitysophila were comprehensively analyzed by combining Maxent ecological niche models with geographical information system technique in this paper.The relatively exactly potential distribution region of Hemiberlesia pitysophila in whole Chi...
本文选用Maxent生态位模型与地理信息系统相结合,综合分析影响松突圆蚧生长发育的环境因素,结合寄主分布特征,非常直观定量地获得了松突圆蚧在我国的潜在发生区,计算结果经ROC曲线分析法验证,Maxent生态位模型的AUC值为0.991(非常接近于1),表明预测获得了较好的效果,研究可为松突圆蚧的检疫及防治决策的制定提供科学依据。
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Chapter 5: The fluorescence quenching reactions of barbaloin with serum albumin in solution were studied. The quenching mechanism of serum albumin by barbaloin was interpreted using the Stern-Volmer mechanism. The binding constant K values and the number of binding sites were calculated, respectively.
第五章:首次研究了芦荟甙与血清蛋白在溶液中的相互作用,利用Stern-Volmer方程解释了芦荟甙对血清蛋白的荧光淬灭,并测定了不同温度下的结合常数及结合位点数。
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It may be used as a screening index of bilirubinic encephalopathy in clinics.
新生儿血清CK-BB增高与高未结合胆红素血症造成的脑细胞损害有关,CK-BB可作为临床监测高未结合胆红素血症新生儿胆红素脑病的一个筛选指标,值得临床推广。
- 推荐网络例句
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This one mode pays close attention to network credence foundation of the businessman very much.
这一模式非常关注商人的网络信用基础。
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Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.
扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。
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There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.
双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。