与...同时发生

On the basis of the kinetic equation of substrate reaction in the presence of urea or guanidine hydrochloride, all microscopic kinetic constants for the free enzyme and enzyme-substrate binary and ternary complexes have been determined. The results of the present studies indicate that:①In the presence of urea or guanidine hydrochloride, enzyme-substrate complexes lose their activity less rapidly than the free enzyme. Therefore, both substrates, NADPH and 7, 8-dihydrofolate, protect dihydrofolate reductase against inactivation.②The denaturation of dihydrofolate reductase by urea follows single-phase kinetics, and changes in enzyme activity and tertiary structure proceed simultaneously in the unfolding process, so it may be an"all or none"process.③The GdnHCl-induced unfolding of the dihydrofolate shows a biphasic transition, while the change in the enzyme activity is a single exponential process. The rate constant of inactivation is consistent with that of the fast conformational change. Therefore, the kinetic intermediate of protein unfolding should be a partially folded and inactive form.

我们根据在脲或盐酸胍存在下的底物反应动力学方程求得游离酶和酶底物二元、三元复合物的微观动力学常数，结果表明：①酶-底物二元、三元复合物的失活速度明显慢于游离酶，说明两个底物二氢叶酸和NADPH对酶的失活都具有一定程度的保护作用；②在脲作用下，酶的失活和构象变化均为单指数项过程，而且酶的活力丧失和三级结构变化是同时发生的，说明二氢叶酸还原酶的脲变性可能是一个"全或无"的两态过程；③在盐酸胍作用下，酶的构象变化为两相过程，而失活则是单指数项过程，酶分子构象变化的快相速度常数与失活速度常数基本一致，因此我们认为二氢叶酸还原酶的盐酸胍变性过程中存在一个没有活力、但仍具备一定空间结构的变性中间体。

You will meet your Galactic brothers and sisters in all planes simultaneously, including the physical plane.

你们与你们的星际兄弟姐妹们的是同时发生在所有的，包括。

The stratigraphic trend develops during lithification and is unrelated to any change in the global oceanic δ13C.

地层在成岩作用的同时发生的变化应该与全球海洋δ13C 的变化没有多大的联系。

Trips are often planned to coincide with local food festivals or special events.

这种"赚钱旅游"是与外地所在国的美食节或一些特别的庆典活动同时发生。

Almost simultaneous with this introduction of Methodism into New York was its planting in Maryland.

几乎同时发生的，这与引进methodism到纽约，其种植在美国马里兰州。

In any tragedy which still retained the stamp of its Dionysiac origin, this Discovery and Peripety might normally be expected to occur, and to occur together.

在所有依然保留有酒神起源印记的悲剧中，发现与逆转这两个要素一般都存在，而且是同时发生。

We describe an event of sequential change of adenoma-carcinoma in a patient with polyposis of the colon.

我们叙述一个腺肿与癌症演变的现象，并同时发生在一个大肠息肉症的病人身上。

The resistance to the Pope's authority ... is pretty nearly coincident with the rise of the Ottomans.

对教皇权威的反抗与奥斯曼土耳其人的兴起几乎同时发生。

The resistance to the Pope 's authority.is pretty nearly coincident with the rise of the Ottomansjohn Henry Newman.

对教皇权威的反抗与奥斯曼土耳其人的兴起几乎同时发生。

Because oxidations always go hand in hand with reduction, we refer to these reactions as redox reactions.

由于氧化反应总是与还原反应同时发生，所以我们称这些反应为氧化还原反应。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失