不稳定性

The association between the multidirectional instabilities and the vertebral injuries to each of load-sharing point score was analyzed.

针对每个载荷分担点评分的椎骨损伤与多向不稳定性之间的相关性被予以分析。

The association between the multidirectional instabilities and the ertebral injuries to each of load-sharing point score was analyzed.

针对每个载荷分担点评分的椎骨损伤与多向不稳定性之间的相关性被予以分析。

These restrictive con d itions can be taken as practical design criteria for avoiding reactor instabilit y and temperature sensitivity in multitubular packed-bed reactors.

这些条件也可以作为避免列管式固定床反应器不稳定性和温度灵敏性的实用设计判据。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Objective: To explore the relationship between the genetic instability of microsatellite and the evolution of chronic myelogenous leukemia.

目的：研究微卫星DNAs的遗传不稳定性与慢性粒细胞白血病加速、急变的关系。

Because of the solubility of carbonate rock,the instability of karst soil and the vulnerability of karst vegetations,the risk of water and soil loss is bigger in carbonate rock areas than in noncarbonate rock areas.

由于碳酸盐岩的可溶蚀性、所形成土壤的不稳定性及碳酸盐岩植被的脆弱性等特征，在碳酸盐岩区水土流失的风险较非碳酸盐岩区更大，水土流失敏感性受岩性的影响比非碳酸盐岩地区更明显。

It can be in the form of spurious signals If the amplitude of these spurious signals is outside agency-reference-recommendation value, they could cause undue disturbances to other users by entering the receiver systems of other RF bands The generation of spurious signals from a transmitter could be the result of imposed varying antenna loads, noisy voltage-supply lines to the stages of the transmitter, or noncontinuous battery-voltage supply to RF energy from the host.

传输器的不稳定是指传输器产生的伪真信号，这种不稳定性的伪真信号的形成出现，如果它们的振幅超过代理服务器允许值就会进入其它波段的接收系统，干扰使用者，强制性的天线改装，伴有嗓音的电压，断续的供电都会产生为伪真信号，有些电池装配线可接收并解调这种能量，并生成嗓音，然后由经供电线路进入主传输器。

These tasks seem to depend on the unusual nonequilibrium dynamic behaviors of MTs.

微管的功能依赖于其动态不稳定性。

Daily hemodialysis may be associated with less severe hemodynamic instability, less ischemia, lower incidence of progression to oliguria, and more rapid recovery.

每日的血液透析治疗，可以使严重的血液流动不稳定性、贫血症、进行性的尿少症发病率更少，患者恢复的速度也更快。

Her installations like "Overflown" and her paintings like "Making Up" all reflect the instability and insecurity of women in the society.

无论是她的装置作品《溢》，还是绘画作品《上妆》，都是关注女性在社会的生存状态中的不稳定性以及不安全感。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。