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To investigate whether the expression of cdc2 and cyclin B1 in spermatogenic cells during spermatogenesis is actually a temperature dependent event, in situ hybridization, Western blotting and immunohistochemistry analysis were used to study the expression of cdc2 and cyclin B1 in normal and cryptorchid testis. Results showed that heat would differentially hurt male germ cells in different developmental stages during spermatogenesis, especially the pachytene primary spermatocytes. Most of spermatogonia in contralateral cryptorchid testis were not harmed fatally by heat as yet, indicating that spermatogonia could resist to beat to a certain extent. In this case spermatogonia could develop to pachytene/diplotene primary spermatocytes, but they could not acquire the ability to complete the transition from mitosis to meiosis, and then appeared to go through apoptosis. Therefore, we could not find the descendants of meiosis: secondary spermatocytes and round spermatids, elongated spermatids and spermatozoon. The abdominal temperature had no significant influence on the transcription of cdc2 and cyclin B1 in the spermatogonia and pachytene/diplotene primary spermatocytes. In normal rabbit testis, cyclin B1 increased in the pachytene/diplotene primary spermatocytes before meiosis and reached its peak in the spermatids.

为了解精子正常发生过程中cdc2和cyclin B1表达的低温依赖性,我们利用原位杂交和免疫组化等方法,研究了正常和隐睾精子发生过程中cdc2和cyclin B1的转录和翻译调控活动,结果表明:(1)热对各阶段的雄性生殖细胞都有损害,粗线期的初级精母细胞尤为敏感,实验性隐睾内的精原细胞尚未完全受到"致命"影响,说明精原细胞对热有一定的耐受性,但即使成为粗线期/双线期初级精母细胞,却未能获得由有丝分裂过渡到减数分裂的能力,呈现不同程度的凋亡,所以在整个切片中找不到源自减数分裂的产物----次级精母细胞、圆形精子细胞,更谈不上长形精子细胞和精子的形成;(2)腹腔高温未明显地影响隐睾精原细胞和粗线期/双线期初级精母细胞中cyclinB1和cdc2的转录,说明高温并不是通过影响cyclin B1和cdc2的转录活动而导致生精过程阻断的;(3)正常兔睾丸组织中,〓在精原细胞和粗线期/双线期精母细胞中均有表达:cyclin B1蛋白在减数分裂前期的粗线期/双线期初级精母细胞中的表达量增加,于变态末期的精子细胞中达高峰。

Based on plentiful isotopic dating data and geological studies, the authors, in this paper, discuss the geological meanings of the two isotopic ages given by Lapierre et al., and conclude:① Mesozoic volcanic activities in Zhejiang are most frequent in 130~83 Ma, that is, from the early to late Cretaceous but not the late Jurassic;② The Jiande and Moshishan groups are nearly in the same period and not in an upper—lower stratigraphic relationship with each other;③ The period of 110~100 Ma is a transitional stage from the early high-K calc-alkaline dacite—rhyolite associated with diorite—granodiorite) to the late basalt—rhyolite(associated with K-feldspar granite—alkali granite).

本文就Lapierre等文中124 Ma和97 Ma两个年龄的地质意义、幕次划分以及浙西与浙东火山岩时代对比作出评论,并厘定浙江中生代火山岩时代归属,提出:①浙江中生代火山活动时代为132~83 Ma;②浙西建德群与浙东磨石山群火山岩并不存在上下关系,地质接触关系、古生物组合和大量同位素定年数据都不支持Lapierre等的浙西与浙东火山活动幕次的对比方案;③ 110~100 Ma为早期高钾钙碱性英安岩—流纹岩(伴生闪长岩—花岗闪长岩)向晚期玄武岩—流纹岩(伴生钾长花岗岩—碱性花岗岩)过渡的转折期。

While activities such as these have cash flow implications for a firm, we argue that it is difficult, or impossible, to disaggregate the results of operations into individual performance measures that cleanly isolate the effects of the different activities.

而这些活动的现金流量的影响是坚定的,我们认为这是困难的,或者不可能分类经营结果纳入个人业绩的措施,cleanly孤立了不同的活动。

Pleasure is an important component of life, and decreasing the number of displeasing activities that you undertake, as well as increasing the activities that give you pleasure, will increase your happiness level.

快乐是生活一个重要组成部分,减少你所做的不愉快活动,并增加你有兴趣的活动,这会提高你的幸福水平。

During the promotion period, if you don't take part in the above 1st and 2nd round award program, you can also join our double point mileage program.

活动期间,如果您不参加上述一、二重奖励,还可以参加双倍积分活动,更多的选择等着您。

When Egeria writes of ceremonies held on the Octave of Easter she is not clear. While, throughout the eight days, the Lazarium was decorated and adorned like for the Octave of the Epiphany, the ceremony of the fifth day took place, not at Bethany, but at the Anastasis. Thus, there is no sure proof that a special assembly took place at Bethany during the Octave of Easter.

当时,Egeria并不清楚她所描写的是复活节八日庆的礼仪,因为,整整八天,拉匝禄被装饰的像是为了主显节八日庆,庆祝活动在第五天举行,但地点不是在伯达尼,而是复活之地,因此,没有证据证明复活节八日庆期间有特别的庆祝活动是在伯达尼举行。

Industry and finance seem to him to be activities unworthy of gentlemen, although, alas, many are forced by exigencies of circumstance to take some part in them.

在他看来,实业和金融是不值得绅士从事的活动,呀,虽然许多人由于境况所逼又不得不在某种程度上参与这种活动。

It is in the two dimensions of foreignization and familiarization that literature discourse multiply update.

作为文学艺术的审美活动显然是人类不同于一般动物的一种特殊的高级活动。

At present under the socialist market economy condition, completes the enterprise staff thought political work the key is the Central Party Committee 17 big spirits in every sense of the term implementations basic unit Since the specially reform and open policy, has had many head of undertaking, deceives both superiors and subordinates works for one's own interests under the guise of working for the public, thought the present does not have the movement, in the waist the animal pen axe, the fan which in the hand takes, often on greatly sends the arms, teaches whips the staff, often on to the authority coerces the staff, simply not staff when the person looked, the wages casually decides, bully softly, is hard feared, pays out the wages not to have the pay list, wants to give how many to give how many, Sunday does not let the staff rest, does not pay adds the spot to spend If you offer an opinion to him, regards you is the thorn in one's side, the thorn in the side, does everything possible to carry on retaliates you, and direct descendant wilfully tolerates using the hand in authority to oneself, to give the green light to something, to holds the different political view greatly to open killing They use in the hand two "magic weapon" to benefit as the third party in a dispute, deceive both superiors and subordinates flatter the higher authority, exploits power, violates the country head of undertaking the cadre relative about to forbid in this enterprise to be engaged in production management the stipulation Also uses in the hand the authority private full center pouch, is greedy, does everything possible to concoct pretexts makes the forged account, high keeps off the office supplies with the government money purchase modern age to converge the oneself to have, makes the forged account to reimburse the beach person cost, digs national the corner of a wall Then receives using the duty gives the sales commission,包产 outside the package exits the enterprise outside, fishes for the wealth, even allies the annual bonus, violates the country and the enterprise stipulated, then 参股using the duty manages the enterprise But greatly gives the discount in the staff benefit treatment aspect, in 工资分 is joined to greatly makes the issue, drills the national policy spatial, borrows the wage reform is the excuse, seeks the benefit for own clique, borrows the work then to provide the special sedan car for the enterprise basic unit leadership, all expenses completely are responsible by the unit, to become not to pay the solid private sedan car The party and the country stressed repeatedly that, strictly prohibits the leading cadre to exploit power, but such stipulation into head of undertaking cadre's neglected advice, really it may be said in has the policy, gets down has the countermeasure If the country does not carry on effective supervising and managing to the enterprise, does not carry on the strengthened management, gets down for a long time, they can depend on right and not the improper income become the millionaires and surely the wealthy man, the state asset can massively drain, but government's policy can become a mere scrap of paper, loses it in common people's prestige Let these clothes eating insects embezzle national the property, thus causes the enterprise to move towards goes out of business, such example is too numerous to cite individually The working class is the national master, such formulation until now is does not have the question, but present working class's actual condition how?

目前在社会主义市场经济条件下,做好企业职工思想政治工作的关键是把党中央十七大精神不折不扣的贯彻到基层。特别是改革开放以来,有不少的企业领导,欺上瞒下假公济私,认为现在没有运动,腰里苄着斧子,手里拿的扇子,动不动就大发干戈,训策职工,动不动就以权力要挟职工,简直不把职工当人看,工资随便定,欺出软,硬出怕,发工资没有工资单,想给多少给多少,星期天不让职工休息,不付加斑费。如果你给他提意见,就视你为眼中钉,肉中刺,想方设法进行报复你,利用手中的权力对自己和嫡系任意纵容,大开绿灯,对持不同政见者大开杀界。他们用手中的两件"法宝"渔翁得利,欺上瞒下讨好上级,以权谋私,违反国家关于企业领导干部亲属禁止在本企业从事生产经营活动的规定。还利用手中的权力私饱中囊,多吃多占,想方设法巧立名目做假帐,用公款购买现代高挡办公用品归为己有,做假帐报销滩人成本,挖国家的墙角。利用职务之便收授回扣,把企业外包产品外包出去,从中捞取钱财,甚至加盟人股,违反国家和企业规定,利用职务之便参股办企业。而在职工福利待遇方面大打折扣,在工资分配上大做文章,钻国家政策的空,借工资改革为借口,为自己的小集团谋利益,借工作之便为企业基层的领导配备专门的小轿车,一切费用全部由单位负责,成为名不付实的私家小轿车。党和国家一再强调,严禁领导干部以权谋私,而这样的规定成为企业领导干部的耳旁风,真可谓上上有政策,下有对策。如果国家对企业不进行有效监管,不进行强化管理,长期下去,他们会靠正当和不正当的收入成为百万富翁和千万富翁,国有资产就会大量流失,而政府的政策就会成为一纸空文,失去其在老百姓中的信誉。让那些蛀虫侵吞国家的财产,从而使企业走向倒闭,这样的例子不胜枚举。工人阶级是国家的主人,这样的提法至今是没有问题的,可是现在的工人阶级的实际状况又如何呢?

Third, immerge corporate culture in corporate runningCorporate culture is a sort of concept of values not recreational activities, belongs to social consciousness.

再次要企业文化建设于企业经营活动之中。企业文化不是蹦蹦跳跳的娱乐活动,企业文化是一种价值观念,属于社会意识范畴。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?