不及

In clinical. acetylcholinesterase inhibitors reduce the breakdown of synaptic acetylcholine, have been modestly effective in improving the cognitive deficits of Alzheimer's disease.The goal of this work is to determine enzyme kinetics and mechanisms of acetylcholinesterase and butyrlcholinesterase inhibition by five cardiovascular drugs, lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride, and two benzodiazepines, diazepam and chlordiazepoxide hydrochloride. All drugs in this study are reversible mixed-type inhibitors of acetylcholinesterase and butyrylcholinesterase. The pKi values for acetylcholinesterase and butyrylcholinesterase inhibition by the cardiovascular drugs are linearly correlated with the molecular weights of the drugs with the slopes of 0.005 and 0.0021, respectively. Therefore, van der Waals' interactions between acetylcholinesterase and the cardiovascular drugs are stronger than those between butyrylcholinesterase and the drugs. This is probably due to a smaller active site gorge and a more significant peripheral anionic substrate binding site of acetylcholinesterase than those of butyrylcholinesterase.

本研究之目的系决定乙醯胆碱酯酵素和丁醯胆碱酯酵素被五种心脏血管药物lovastatin， simvastatin， amlodipine besylate， nifedipine、hydralazine hydrochloride和两种benzodiazepines：diazepam和Chlordiazepoxide hydrochloride的抑制作用之动力学及机转，这些药物都是乙醯胆碱酯酵素和丁醯胆碱酯酵素的可逆性、混合型之抑制剂，实验结果显示，五种心血管药物对於乙醯胆碱酯酵素及丁醯胆碱酯酵素抑制之pKi值和药物之分子量呈直线之关系，斜率分别为0.005及0.0021因此丁醯胆碱酯酵素，与心血管药物间之凡德瓦作用（van der Waals' ）比乙醯胆碱酯酵素与心血管药物间者弱，这可能原因是丁醯胆碱酯酵素之活性区域比乙醯胆碱酯酵素之活性区域更宽广，但丁醯胆碱酯酵素之周边阴离子区域不及乙醯胆碱酯酵素之周边阴离子区域者明显重要，由於五种心血管药物对於乙醯胆碱酯酵素和丁醯胆碱酯酵素抑制之pKi值存在著线性关系表示此种抑制作用系经过共同之反应机理。

Emily loved The Pilgrim's Progress. Many a time had she walked the straight and narrow path with Christian and Christiana --although she never liked Christiana's adventures half as well as Christian's.

她多少次跟随着书中的基督徒和女基督徒一起走过那些又长又窄的小路——尽管她对女基督徒的历险的喜爱还不及基督徒的一半。

As research and extensive, gradually discovers that the seeastigmatism formula also have problems, that is, it has a data expression cannot and Visual feeling of one's eyes, so the match chromatology experts have implemented written by CMC (1 c) CIE94 seeastigmatism seeastigmatism formulas, the formulas as well as the latest CIEDE2000 seeastigmatism formula, where written by CMC (1 c) chromatic aberration formula in the textile industry is listed as a range of international and national standards. X-Rite ′?ˉs 528 integrates CIE LAB color difference equation, written by CMC (1 c) and the color difference formula, the formula CIE94 seeastigmatism seeastigmatism measurement shall be free to choose from.

随着查究的浮浅，忽然发掘该色差公式也有题目，即它的数据外达不克不及够和人眼的触觉感施相成婚，因此色彩教查究大师接踵推出了CMC(1∶c)色差公式、CIE94色差公式以及最新的CIEDE2000色差公式，其洋CMC(1∶c)色差公式在纺织行业被列为不国外和国度尺度。X-Rite 528集不败了CIE 1976 LAB色差公式、CMC(1∶c)色差公式和CIE94色差公式，在色差丈度时可以自由拔取。

I am going to play in Cincy, and I cannot wait to get out there!!!!

我将会去到 Cincy 参赛，我等不及要到那里去了！！！！

Treatment by rational design of stamp inks components, stamp inks and glaze made from mixed ground from coacervate.

办理的办法是：公道安排印油不败不合，印油与色釉搀和研磨后不克不及爆不收固不解本体。

The Cobden turbine was far less complex and far less expensive to manufacture than a typical high speed power generation turbine, but it was also far less efficient.

这种科布登涡轮机在制造方面远不及—般的高速发电涡轮机复杂和昂贵，但是它的效率也差很多。

Like the Quaestiones, the Courts of Queen''s Bench, Common Pleas, and Exchequer were all theoretical emanations from a higher authority, and each entertained a special class of cases supposed to be committed to it by the fountain of its jurisdiction; but then the Roman Quaestiones were many more than three in number, and it was infinitely less easy to discriminate the acts which fell under the cognisance of each Quaestio, than to distinguish between the provinces of the three Courts in Westminster Hall.

正和"审问处"一样，后座法院（Court of Queen''s Bench）、民事高等法院和理财法院在理论上都是从一个较高的权威分出来的机关，并且每一个机关都分别主管一类特种案件，这类案件被假定是由其管辖权的泉源委托给它的；不过当时罗马"审问处"在数量上远不止三个，如要把分属于每一个"审问处"审判权的各种行为加以区别，远不及把韦斯敏斯德三种法院的范围加以划分那样便当。

Time comes to Zhou Yi in an instant (on June 30), I send color scheme to give opposite party with respect to online preparation early in the morning, result when much at 10 o'clock ability sees the line on the other side (I urge if it were not for he still does not know he is in be absent, the working hours that their government says was at 9 o'clock 17: 30), I send a graph to give opposite party, waited as a result very long, because he says to want to be touched with the technology, half hour went, I wait not as good as occupied still, do I say to still do not have a result, I should go out immediately, quickly reply.

时间转眼来到了周一(6月30日)，我一早就上网预备发风格图给对方，结果等到了10点多才见对方上线(要不是我催他还不知道他在不在呢，他们官方说的工作时间是9点17：30)，我发图给对方，结果等了好长时间，因为他说要跟技术碰一下，半个小时过去了，我等不及了还有事，我说还没有结果吗，我马上要出去了，快点回话啊。

B. line, field of business card printing and membership card making effect and color saturation are not, and other business card printing and membership card

B。 在线条、实地的制卡和会员卡制作效果及色彩的饱和度上不及其他制卡和会员卡制作方式

First, the file cannot be RIP separation to color business card printing and membership card making very inconveniencedby.

首先是文件不克不及被RIP不合色，给不不黑白制卡和会员卡制息带来极不小便利。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。