不刺激的

Secondly, in this study, China's staple food demand is offered to have both long-term and short-term stability, and it fits the "best linear unbiased estimator", goodness of fit , hence it is predictable and has long-term developing co-relation--the rise of food consumption causes the rise of food price and the increase of food consumption stimulate the increase of income.

实证结果发现：中国粮食长、短期发展具稳定性、最小变异线性不偏估计式(best linear unbiased estimator，BLUE)、有配适性且残差变异数齐一，亦无自我相关性、故具可预测性与长远发展关系，乃粮食消费增加，刺激粮食售价的攀升；粮食消费量增加，刺激所得增加。

However, too often some of the reasons may be related to the following: the one, local stimulus, such as perineal cleaning baby care too much, genital eczema, pinworm, wet diapers or pants too tight and so on stimulation. 2, psychological factors, if the children were the family atmosphere of tension, lack of motherly love, suffer discrimination and so emotionally can not be met through its own stimulus to seek vent, resulting in leg movements folder. 3, larger children may be related to puberty by sex-related stimuli.

但过于频繁可能与以下一些原因有关：1、局部刺激，如对孩子会阴部清洁护理过多、外阴湿疹、蛲虫、尿布潮湿或裤子太紧等等的刺激。2、心理因素，如有的儿童因家庭气氛紧张、缺乏母爱、遭受歧视等，在感情上得不到满足，通过自身刺激来寻求宣泄，从而产生夹腿动作。3、大一点的的孩子可能与进入青春期、受到与性有关的刺激有关。

RESULTS: Both resting B cells and T cells did not express PD-L1 on their surface, however PD-L1 expression was significantly up-regulated on the surface of the activated B cells after 6 h stimulation with LPS or pokeweed mitogen, and the percentages of B cells that expressed PD-L1 reached a plateau at 24 h, which were (46.26±10.71)% with LPS and (43.67±6.14)% with PWM stimulation, respectively. No markedly change of PD-L1 expression on the surface of the activated T cells after stimulation with LPS was observed, but upregulation of PD-L1 expression was observed when stimulation with PWM.

结果： 静息B细胞和T细胞表面不表达PD-L1，LPS和PWM刺激6 h后表达PD-L1的B细胞百分率均显著高于静息B细胞，24 h达到最高，分别为(46.26±10.71)%和(43.67±6.14)%，之后随时间延长而降低；表达PD-L1的T细胞百分率在LPS刺激下无显著变化，但PWM刺激6 h后百分率明显高于静息条件，24 h达到最高，为(25.42±9.23)%，之后下降。

Results:(1)NSCs form typical neurospheres under adequate concentration in vitro, which are immunoreactive to Vimentin. Typically and terminally differentiated mature neural cells could not be found without the stimulus of mitogen or only under NSCs self-regulation and self-induction;(2)NSCs derived from hippocampus maintain the character of stem cells much longer with better biological behavior; NSCs passed to the 2-3 passage are the best to graft since they have not differentiated;(3)NSCs cultured in vitro could self-regulate and differentiate into neurospheres and progenitors positively immunoreactive to specific antibodies representing neurons, astrocytes, oligodendrocytes and Schwann cells;(4)There are widespread synaptic contacts between various kinds of descendent clones and cells;(5)Neurospheres could be formed without the stimulus of mitogen when NSCs and OECs are cocultured. Many neurospheres and cells immunoreactive to Vimentin, GFAP, MAP2, 02, p75NGFR, GFAP, S-100, Synaptosis, Vimentin, Tau (Tau is only positive in cocultureof HNSCs+HOECs) could be found;(6)The supernatant fluid triturated from adult rat spinal cord stimulates NSCs to differentiate into neurons, but do not terminally differentiate;(7)Fibroblasts and O4 oligodendrocytes are not supported to grow under this culture medium.Part II: Isolation, culture and identification of rat and human olfactory ensheathing cellsOlfactory ensheathing cells/glials are the most powerful cells to enable the regeneration of axons in the central nervous system.

结果表明：①在适宜的浓度体外培养条件下，NSCs能形成典型的神经干细胞克隆球，Vimentin免疫荧光染色阳性，单靠丝裂原刺激或NSCs自我调节和分化诱导，不会产生典型的终末分化的成熟神经细胞；②海马源性的NSCs维持干细胞特性的时间更长，生物学特性更优；③传至第2～3代的NSCs尚未分化时移植最佳；④体外培养的NSCs能自我调控分化为神经元、星形胶质细胞、O2少突胶质细胞、雪旺氏细胞染色阳性克隆球和前体细胞；⑤各种子代克隆球和细胞存在广泛的突触联系；⑥NSCs与OECs联合培养时，不需丝裂原刺激即能形成克隆球，获得大量Vimentin、GFAP、MAP2、O2、p75NGFR、GFAP、S-100、Synaptosis、Vimentin、Tau(Tau只有人HNSCs+HOECs联合培养时出现阳染)染色阳性的克隆球和细胞；⑦脊髓研磨后的上清液刺激神经干细胞向神经元方向分化，但并不出现终末分化；⑧本研究培养条件不利于成纤维细胞、O4生长。

Stressing on "fine reputation","quality","service","credit","practice", not only the grandeur.④Encouraging the innovation, not the unearthliness, playing down the effect of entertainment stars or idols, decreasing the fashion index.⑤"personality" is not the "self central". Social sense of responsibility and interpersonal "feeling of affinity" are both intensified.3.1.2 Factor analysis, revealing 19 value element vectors, which include "comfort","personality","simple","fine reputation","responsibility","service","price","wisdom","distinction","enthusiasm","stimulation","taste","sex difference","quality","vigor","idol","fashion","affinity","aesthetic" and so on. Four orientation diagrams coordinated with the average factors and the standard deviations of these 19 value elements, described the multi directional value orientation structure for China college students' sportswear consumption.3.1.3 Clustering analysis are applied to classify the former 19 value elements, which discovered that three inferior group are classified from the college students' consumption group based on the whole specimen data. It could be the reference of enterprise brand building for the orientation of consumption values.3.2 General personal values, self conception and demographic are lead into as three major variables for the interrelationship analysis of sportswear consumption value system.3.2.1 Firstly, the college students having their general values and existing the inferior group feature regarding to the consumption values.

三、研究的主要成果及其意义对中国大学生休闲服消费价值体系进行探索性分析1、首先对中国大学生休闲服消费价值观量化问卷所调查的样本数据进行频数统计趋向性分析，发现呈现的主要特点有：(1)"个性化"和"简约"已成为潮流，而寻"刺激"、找"激情"总体收敛；(2)追求"美感"，更不放弃"舒适"，两者兼得才是完美；(3)重"美誉"、讲"质量"，重"服务"、讲"信用"，求实际、不求高贵，"明智"有素；(4)求新不求怪异，明星、偶像效应淡化、时尚指数不高；(5)"个性化"不是"唯我化"，社会责任感和人际"亲和力"在强化。2、其次对样本数据进行因子分析，揭示出以"舒适"、"个性"、"简约"、"美誉"、"责任"、"服务"、"价格"、"明智"、"独特"、"激情"、"刺激"、"品位"、"性差"、"质量"、"活力"、"偶像"、"时尚"、"亲和"和"美感"等十九个价值元素为矢量的休闲服消费价值体系，并以因子均值和标准差为参数勾画出19个价值元素坐标四方位图，从总体上描述了中国大学生休闲服消费多维的价值取向结构。3、再者进行聚类分析，对上述十九个休闲服消费价值元素作不同量值的分类，发现在样本总量中可以细分为有较大区分度的三个类别，呈现出大学生消费群体中存在休闲服消费价值体系不同的亚群体，可为以消费价值观为取向的企业品牌价值定位提供参考基谱。

Sustained AF could be induced easily in all dogs during vagal nerve stimulation in vivo both before and after isolation of all PVs with encircling lesions created by a bipolar radiofrequency ablation clamp device. PV elimination had no effect on atrial effective refractory period or its responses to cholinergic stimulation. Autonomic ganglia were identified by bradycardic and/or tachycardic responses to high-frequency subthreshold local stimulation. Ablation of the autonomic ganglia overlying all PV ostia suppressed the effective refractory period-abbreviating and AF-promoting effects of cervical vagal stimulation, whereas ablation of only left- or right-sided PV ostial ganglia failed to suppress AF.

无论是在双极环状消融所有PV之前或之后，在体刺激颈迷走神经节过程中持续性房颤在所有犬均能轻易被诱导出，PV切除对心房肌的有效不应期或对胆碱的反应均没有影响，通过对高频的域下刺激发生快速或慢速反应来鉴定自主神经节，消融叠加于PV口部的自主神经节能抑制有效不应期的缩短、和刺激颈迷走神经诱发的房颤促进作用，而仅消融左或右侧PV口部的自主神经节却不能抑制房颤。

Stimulation at this site is typically delivered at low frequencies in contrast to the high frequency stimulation required for therapeutic benefit in the subthalamic nucleus.

在这个位点的治疗刺激一般采用低频刺激而不是像亚丘脑核这样使用高频刺激。

The results of in situ hybridization showed that the gene of Mdde was expressed mainly in epidermis of the body wall and fat bodies, and no expression signal was detected in tracheae, intestine and musculature. The gene of Mdde in epidermis expressed both in challenged larva and no-challenged larva, whereas the gene of mdde in fat body expressed only in challenged larva.

原位杂交的结果表明：Mdde基因在家蝇幼虫体内主要表达于表皮和脂肪体，在气管、肠和肌肉组织中没有检测到Mdde基因的表达；表皮中Mdde基因在微生物刺激前后均有表达，而脂肪体中Mdde基因经微生物刺激后才表达，刺激前不表达。

The latedischarges decreased from 9.29 ± 0.97 to 6.71 ± 0.68 with the A-fiberconditioning stimulus increasing from 1 to 5 (n〓8, P〓0. 05).(7) The intervalbetween the conditioning stimulus and test stimulus (C-T interval) wasincreasing, the inhibition tended to plateau off. At shorter time intervalsthe inhibition became more effective. When C-T interval was limited in 50ms,the inhibitory effects was the strongest, here, the late discharges reducedfrom 12.57±1.21to 2.29±0.42 (n=11, P＜0. 01).(8) Behavior research showedthat the rat model of snake venom exhibited neuropathic pain with heathyperalgesia, cold and mechanical allodynia, which corresponding to the acuteelectrophysiological findings.

此时轻刷WDR神经元的感受野不能引起其活动改变，但伤害性齿镊夹捏仍可引起WDR神经元放电增多；〓5〓晚成分放电的潜伏期缩短，即宁静期的时程变短，由给蛇毒前的118.83〓3.67ms降至50.72〓1.36ms〓n〓32，P〓0.01〓；〓6〓在正常动物，如果预先给予只激活A纤维的弱条件电刺激〓mA，100μs〓可抑制随后的伤害性检验刺激所诱发的WDR神经元的晚成分放电，当条件刺激个数从1增加至5时，每次伤害性检验刺激所诱发的晚成分放电数从9.29〓0.97个降至6.71〓0.68个〓n〓8，P〓0.05〓；〓7〓固定条件刺激数为1个，当条件刺激与检验刺激之间的间隔增大时，A纤维条件刺激对WDR神经元晚成分放电的抑制作用逐渐减弱，当条件刺激与检验刺激之间的间隔在50 ms以内时，抑制效应最为显著，此时，晚成分放电数由正常时的12.57〓1.21个降至2.29〓0.42个〓n〓11，P〓0.01〓；〓8〓与急性研究中的WDR神经元电活动的变化结果相匹配，利用蛇毒制备的大鼠模型在行为学上表现为热痛觉过敏、冷觉的痛性感觉异常及机械痛觉过敏等慢性痛症状。

At the same time, most WDR neurons failedto respond to the light brush applied to the receptive fields, but they couldbe intensively excited by the noxious pinch.(5) The latency of the latedischarges was shortened from 118.83 ± 3.67ms to 50.72 ± 1.36ms (n〓32, P〓0. 01).(6) Preceding graded number of A〓fiber conditioning inputs (〓mA, 100 μs) delayed the C-activity evoked by the following nociceptive teststimulus activating both A- and C-fiber applied to the sciatic nerve. The latedischarges decreased from 9.29 ± 0.97 to 6.71 ± 0.68 with the A-fiberconditioning stimulus increasing from 1 to 5 (n〓8, P〓0. 05).(7) The intervalbetween the conditioning stimulus and test stimulus (C-T interval) wasincreasing, the inhibition tended to plateau off. At shorter time intervalsthe inhibition became more effective. When C-T interval was limited in 50ms,the inhibitory effects was the strongest, here, the late discharges reducedfrom 12.57±1.21to 2.29±0.42 (n=11, P＜0. 01).(8) Behavior research showedthat the rat model of snake venom exhibited neuropathic pain with heathyperalgesia, cold and mechanical allodynia, which corresponding to the acuteelectrophysiological findings.

此时轻刷WDR神经元的感受野不能引起其活动改变，但伤害性齿镊夹捏仍可引起WDR神经元放电增多；〓5〓晚成分放电的潜伏期缩短，即宁静期的时程变短，由给蛇毒前的118.83〓3.67ms降至50.72〓1.36ms〓n〓32，P〓0.01〓；〓6〓在正常动物，如果预先给予只激活A纤维的弱条件电刺激〓mA，100μs〓可抑制随后的伤害性检验刺激所诱发的WDR神经元的晚成分放电，当条件刺激个数从1增加至5时，每次伤害性检验刺激所诱发的晚成分放电数从9.29〓0.97个降至6.71〓0.68个〓n〓8，P〓0.05〓；〓7〓固定条件刺激数为1个，当条件刺激与检验刺激之间的间隔增大时，A纤维条件刺激对WDR神经元晚成分放电的抑制作用逐渐减弱，当条件刺激与检验刺激之间的间隔在50 ms以内时，抑制效应最为显著，此时，晚成分放电数由正常时的12.57〓1.21个降至2.29〓0.42个〓n〓11，P〓0.01〓；〓8〓与急性研究中的WDR神经元电活动的变化结果相匹配，利用蛇毒制备的大鼠模型在行为学上表现为热痛觉过敏、冷觉的痛性感觉异常及机械痛觉过敏等慢性痛症状。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。