不凋的

Evidences show that excitotoxcities of excited amino acid and free radical, Ca2+ overload, environmental alteration of neurons, mitochondrial dysfunction and activation of some apoptotic genes may be involved in it.

缺血性脑卒中确切的神经元凋亡机制尚不清楚，目前认为可能与兴奋性氨基酸、Ca2+超载、自由基的毒性作用、神经元生存环境的改变、线粒体功能障碍及凋亡调控基因的激活等因素有关。

With thedevelopment of molecular bioresearch, gene therapy targeting inhibitor of apoptosis proteingot much attention, and it possibly provide a new trend to effectively treat pancreaticcancer.

研究表明，Survivin作为一种新发现的凋亡抑制蛋白(inhibitor of apoptosisproteins，IAPs)，具有抗凋亡和调节细胞周期的双重功能，在人类众多恶性肿瘤中广泛表达，而在正常组织中不表达或低表达。

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果： 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高，4小时吞噬能力达最高峰，8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8，但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论： 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的，并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应，对哮喘炎症的控制具有重要意义

The phagocytosis of apoptotic cells by phagocytes is physiologic and "silent". In this way the apoptotic cells never has a chance to lyse and release pro-inflammation molecules to the extracellular space.

巨噬细胞吞噬早期凋亡细胞是生理性的和"寂静无声的"，凋亡细胞不能裂解和把能引起炎症的分子释放到细胞的空间。

The loading process of trehalose has no effect on apoptosis of platelets. The efficacy of trehalose plus phosphate in suppressing apoptosis of platelets during cryopreservation is superior to that of only trehalose. Compared to 6% DMSO and 2% DMSO plus TS, trehalose plus phosphate can retain the same platelet count, superior hypotonic shock response and platelet aggregatory reaction to ADP, and lower apoptosis rate of platelets. Platelets cryopreserved with trehalose plus phosphate can retain intact ultrastructure.

结论血小板负载海藻糖的过程不会促进血小板的凋亡；海藻糖保存血小板时，联合应用磷酸盐在抑制血小板凋亡方面的效果优于单独应用海藻糖；海藻糖联合磷酸盐冻存血小板的长期效果较稳定，其维持血小板回收率的效果与6%DMSO及2% DMSO联合TS相同，维持血小板低渗休克反应、聚集功能及抑制血小板凋亡的效果优于6%DMSO及2%DMSO联合TS，并能较好地维持血小板的超微结构。

Human umbilical venous endothelial cells were cultured, and were exposed to different concerntrations of HCY with/or not with CuSO4; Cell counting of detached cells were performed with a hematocytometer; the cell survival was monitored by MTT assay and the cellular injury was evaluated by LDH release; Hoechst 33258 staining was used to observe nuclear morphological changes and the apoptosis was measured by DNA agarose gel electrophoresis ;the percentage of apoptosis was quantified by flow cytometry.

体外培养人脐静脉血管内皮细胞，用不同浓度的HCY伴／不伴生理浓度Cu~(2+)与内皮细胞作用；细胞计数板检测脱落细胞率；MTT法及乳酸脱氢酶释放率的测定来衡量细胞的存活与损伤；Hoechst 33258荧光染色观察细胞核形态变化和DNA琼脂糖凝胶电泳检测细胞凋亡，并采用流式细胞术定量测定细胞凋亡率。

It was demonstrated that in the results of both Se-intake and non-Se-intake trained rat muscles, the appearance of unclear cells karyons condensed chromatins karyon's being packed against nuclear membrane and thickening of nuclear membrane changed.

结果发现，无论补硒还是不补硒运动组均有细胞核染色质浓缩及靠近核膜、核膜增厚等典型细胞凋亡的形态结构改变，运动训练可能导致骨骼肌细胞出现凋亡。

Supervital NBS staining Nile Blue Sulphate , a lysosomotropic vital dye which stains embryonic apoptotic, but not necrotic cell death, is employed to identify the occurence and location of apoptosis.

活体胚胎的NBS染色 NBS是一种亲溶酶体染料，可使凋亡细胞着色，而坏死细胞不着色，因而可初步判定细胞凋亡发生的区域和程度。

RESULTS ① TLSFJM could induce apoptosis of PHA plus IL-2-activated mouse thymo cytes;② TLSFJM could induce apoptosis of alloantigen activated human pe ripheral blood mononuclear cells and hold the cell cycle at G1 phase;③ TLSFJM neither influenced the CD25 expression nor induced apoptosis of PMA activated human PBMC .

结果 TLSFJM 在体外可诱导PHA/IL-2活化的小鼠胸腺细胞的凋亡。 TLSFJM 在体外可诱导alloantigen活化的人外周血单个核细胞的凋亡，且把细胞周期阻遏在G1期。 TLSFJM 对PMA诱导的人PBMC活化抗原CD25的表达无明显影响，也不引起凋亡。

Methods: Male Sprague-Dawley rats were subjected to lateral fluid percussion brain injury of moderate severity. bax and bcl-xL mRNA and protein expression was detected by RT-PCR an d immunohistochemistry. In addition to morphological evidence of apoptosis, TUNE L histochemistry was used to identify DNA fragmentation in situ under both l ight and electron microscope, whereas characteristic internucleosomal DN A fragm entation of apoptosis was demonstrated by DNA gel electrophoresis.

在液压脑损伤模型中，应用逆转录聚合酶链反应、免疫组化分别检测大鼠脑创伤后不同时程bax和bcl-xL表达；采用凋亡原位末端标记、电镜超微结构、DNA凝胶电泳观察脑创伤后细胞凋亡的形态和生化特征。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。