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The outcome factor was recovery of renal function (serum creatinine ≤116 μmol/L) in azotemia patients or a 50% reduction of serum creatinine and discontinuation of dialysis in uremic patients,improved for at least three months.

结局因素:氮质血症者血肌酐下降至116 μmol/L以下,尿毒症者血肌酐下降50%以上,并脱离透析3个月以上为阳性结局,死亡者因其肾功能不可能再恢复,因此删失时间为28周。

A predator model with refuge and toxicity is studied. By constructing a suitable Dulac function, it is shown that there is no limit cycle in the first quadrant, thus the globally stability of the equilibrium is proved. Further more, the paper analyzes the influence of refuge, toxicity and harvesting. It is amazing that ① if the death rate of predator is big or the harvesting effort is big, the existence of the predator is unrelated with refuge; if the death rate of predator and the harvesting effort are small, and the refuge is small enough, the population of both species is increased as the increase of refuge;② if d2=0, the increase of d1 has no influence on the prey population, while the population of predator is decreased.

研究一类有避难所、毒素作用和外界捕获影响的捕食系统,通过构造恰当的Dulac函数,证明系统在第一象限没有极限环,从而证明了平衡点的全局稳定性;分析了避难所、毒素、捕获作用对该系统最终种群数量的影响,发现:①当捕食者的死亡率大或其被捕获得多时,两种群的绝灭与避难所的存在无关;当捕食者的死亡率小、被捕获得多且避难所足够小时,随着食饵避难所的增加,捕食者种群数量也随之增加;②当毒素d2=0时,毒素d1的增加对食饵种群最终数量没有影响,而使捕食者种群数量下降。

Results:Part1: Mean serum EPO concentration of CRF patients showed significant lower than that of control. After transplantation, renal function recovered quickly while Hb level increased steadily in 37 patients with immediate graft function. Their EPO concentration increased significantly and double peaks of EPO level were obtained at day 4 and week 4. 4 cases in IGF suffered from post-transplant erythrocytosis. But their EPO concentration did not reach statistical significance. 5 cases developed delayed graft function, without EPO double peaks and their EPO concentrations showed signiffcant lower than that of IGF.

结果:第一部分:尿毒症病人血清EPO浓度明显低于正常对照值。37例立即肾功能恢复者,SCr迅速下降,Hb上升,其血清EPO浓度在术后第4d形成第一个高峰,与术前和正常对照比较均有显著差异,其后开始下降,在术后4w时再次升高形成第二个高峰。4例IGF患者在术后16w左右发展为PTE,其EPO浓度值略增高,但与IGF组患者EPO水平无统计学差异;5例DGF患者术后无典型的双峰特点,EPO水平明显低于同时期IGF组,直到肾功能恢复后才逐渐升高。

YMDD mutation: HBV YMDD mutation were developed in 12 lamivudine recipients, whereas the treated group had no incidence of HBV YMDD variation, there were significant difference between two groups (p=0.000). YMDD mutation resulted in increase of the mean HBVDNA levels (p=0.000), but no contribution to serum ALT diversification (p>0.05). 2. Precore nt1896 mutation: Precore nt1896 mutation incidence had no difference between lamivudine recipients and objects who received combination therapy of Kidney-invigorating Granule and Marine Injection, and patients of HBeAg negative and HBeAg positive had a close incidence of precore mutation as well as. Precore nt1896 mutation had no influence on serum ALT level. The occurrence of precore nt1896 mutation contributed to serum HBVDNA load increased and worse response of HBVDNA extenuation. 3. HBV genotype: The baseline of serum HBVDNA gradually increase in turn of genotype B, genotype C and genotype B/C. Genotype B seemed to obtain higher rate of serum HBVDNA loss and HBeAg/anti-HBe seroconversion after combination therapy of Kidney-invigorating Granule and Marine Injection, differencing with lamivudine therapy.

疗效相关因素研究:1YMDD变异:对照组有12例检出YMDD变异,治疗组无1例检出,两组比较有显著性差异(P=0.000);发生YMDD变异者血清HBVDNA和ALT水平均有所升高,HBVDNA平均水平高于非变异者(P=0.000);血清ALT与非变异者无明显差异(P>0.05)。2前C区nt1896变异:前C区nt1896变异发生率在治疗组和对照组以及HBeAg阴性和HBeAg阳性患者之间均无明显差异(P>0.05);1896c变异对血清ALT水平无明显影响;治疗组发生1896c变异者,其HBVDNA平均水平较之未变异者明显升高(P<0.05),治疗后HBVDNA下降幅度明显低于未发生1896c变异者(P=0.000)。3HBV基因型:血清HBVDNA基础水平在B、C、B/C混合型间存在明显差异(P<0.05),按B型、C型、B/C混合型依次升高;治疗组HBVDNA阴转率、HBeAg/抗-HBe血清转换率,B型似乎高于C型和B/C混合型,但无统计学意义(P>0.05);对照组HBVDNA阴转、HBeAg/抗-HBe改变在B、C、B/C混合型间无明显差异(P>0.05)。

Results The CD4+ cell counts increased 22 cell/L (t=2.08, P=0.03) when compared with the baseline. IL-2 and IFN-γ increased 7.29pg/mL and 3.82pg/mL respectively (t=3.46, P=0.00; t=5.94, P=0.00), while IL-4 reduced 3.71pg/mL(t=8.18, P=0.00); HIVRNA deceased 0.40 lg copy/mL (t=2.65, P=0.02); 6 patients gained weight of more than 2 kg, 10 patients gained weight of no more than 2 kg. The results of blood mutine examination, liver and renal function were normal. No obvious adverse events were observed.

结果 治疗24周,CD4+细胞数较基线值(0周)平均上升22/μL(t=2.08,P=0.03);细胞因子白细胞介素-2和干扰素-γ较基线值分别平均上升7.29pg/mL和3.82pg/mL(分别t=3.46,P=0.00;t=5.94,P=0.00),IL-4下降3.71pg/mL(t=8.18,P=0.00);HIV RNA较基线值平均下降0.40lg拷贝/mL(t=2.65,P=0.02);体重上升>2kg者6例,增减未超过2kg者10例,患者体重评分有效率72.73%;血常规、肝肾功能等结果均在正常范围内;未观察到不良事件。

After 3 months storage, our result showed that (1) color a value of rose liqueur with sucrose treatment had a slower decreased than with fructose treatment,(2) the sample added with caffeic acid or ferulic acid or tea polyphenol showed no significant difference in the color, anthocyanins content, and antioxidant capacity during storage as compared to control, and (3) the total amount of volatile compounds of rose liqueur decreased gradually, however there was one ester volatile formed, hexadecanoic ethyl ester, during storage.

贮藏三个月发现,(1)以果糖勾兑者在储藏试验中,其红色度下降速度较以蔗糖处理者快,建议仍以非还原糖进行勾兑对日后酒液保存较易,且酒液最好能予以避光包装,以避免颜色品质的下降;(2)添加不同之多酚类化合物时发现,添加caffeic acid、ferulic acid和茶多酚对酒液色泽、花青素含量、以及抗氧化能力之降低速度与控制组并无显著性的差异。(3)酒液储藏三个月后,其香气高级醇均有减少之趋势;但有hexadecanoic acid, ethyl ester酯类出现。

No differences in transparency, pH change or quanty of meperidine were observed either in accelerated tests at 40℃ or storage test for six months. Nevertheless, a decrease in pH value without significant changes of transparency and meperidine content was observed in accelerated tests at 60℃ after storage for 15 weeks. The pH value and meperidine content decrease significantly in both types of ampules when subjected to accelerated tests at 80℃ for 15 weeks.

结果显示盐酸配西汀注射液在两种安瓿中经40℃加速试验与储存六个月样品之外观、透光率、pH值和含量均未呈明显变化;加速试验60℃者於15周开始pH值有明显下降,此外,外观、透光率与含量均未呈明显变化;而加速试验80℃者於15周之外观与透光率虽未呈明显变化,但其含量与pH值均明显下降,表示有分解反应发生。

More risk of PIH seemed to be related to those mothers living in the urban areas with age under 20 or above 35, being peasants and having little educational,having had multiple gestations, conceiving in spring/summer or delivering in winter or spring etc.

在分布特征方面,妊高征年均发病率呈下降趋势,即由1995年的10.7%下降至2000年的8.6%,下降了19.6%;城市、年龄(〈20岁或〉35岁)、农民、低文化程度、双胎、春夏季受孕和冬春季分娩者高发。

Therefore, persons of upward social mobility are more influenced by structural factors and personal social and economic factors; persons of downward social mobility and horizontal social mobility are more influenced by life cycle needs, such as marital change.

因此,上升社会流动者受到结构性因素和个人社会经济地位因素影响最大,而下降社会流动者和水平社会流动者受婚姻状况改变等个人生命周期需求因素的影响最大。

Models on three types of social mobility demonstrate the obvious differences of factors influencing residential mobility of persons with different types of social mobility. Persons of upward social mobility obtain more chances of residential mobility in any period of housing reform because of their higher social and economic status, no matter in planning system or market system. Persons of downward social mobility nearly do not enjoy any benefit in housing reform and housing market construction, and consequently have the lowest residential mobility rate. Persons of horizontal mobility only obtain more chances of residential mobility in the most radical period of housing reform.

分社会流动模型则显示出改革开放以来不同社会流动类型人群居住流动所受到的影响因素存在较大的差异,上升社会流动者因为其较高的社会经济地位,在改革的任何一个阶段,无论是计划体制中还是市场体制下都获得了最多的居住流动机会;而下降社会流动者基本未得到住房制度改革的利益,居住流动机率最低;水平社会流动者仅在住房改革最剧烈的阶段获得了较多的居住流动机会。

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