下肢轻瘫

The diagnosis of ALS was established clinically on the basis of the history and physical and electrophysiological examinations. In five patients (cases 1-5), the initial symptoms were spastic paraparesis.

所有21名患者均依病史、体格检查、电生理检查临床确诊为ALS.21例ALS患者中有5例（病例1~5）首发症状为下肢痉挛性轻瘫，在病程进展过程中均出现上运动神经元症状体征，包括肌强直、腱反射亢进、Babinski征，尤以病例2、病例4的患者明显。

Cases 1-5 who presented with spastic paraparesis and other prominent upper motor neurone signs showed high signal on T1-weighted images in the centrum semiovale, corona radiata and posterior limb of the internal capsule which corresponded to the large myelinated fibres of the corticospinal tract Fig.

病例1~5患者表现为下肢痉挛性轻瘫和其他一些明显的上运动神经元症状体征，在T1像上于半卵圆中心、放射冠、内囊后肢处的皮质脊髓束大有髓纤维走行区均可见高信号病灶（图1），在T2、PdWI像上也可见自放射冠延伸至大脑脚的高信号病灶。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。