下皮层

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果：①40只建模大鼠中36只建模成功，建模成功率为90%；②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现，有6只大鼠在3个月后出现白内障，有4只大鼠在喂养接近至6个月时死亡；③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少，减少约61%(P.01)，后极部视网膜明显变薄(P.01)；④电镜观察，视网膜变薄，视杆细胞膜盘紊乱，血管基底膜增厚等表现；⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达，糖尿病组视网膜组织中3个月时可见少量表达，ERK1/ERK2表达部位为神经节细胞层和内核层；6个月时表达强阳性，部位表达不仅见于内核层、神经节细胞层，色素上皮层也见表达。

Thus, salicylate is widely used for studying the mechanisms of tinnitus. The aim of the present study was to investigate the effects of salicylate on voltage-gated sodium, potassium and calcium channels in the inferior colliculus and the auditory cortex neurons by use of the whole-cell patch clamp method, in order to obtain insight into the relations of tinnitus and voltage-gated channels.

本研究首次将膜片钳的实验技术和离子通道的基础理论引入耳鸣中枢机制的研究中，利用全细胞膜片钳记录技术，观察水杨酸钠对大鼠听觉通路上的两个重要部位——下丘、颞皮层的神经元细胞膜上电压门控性钠、钾、钙离子通道特性的影响，探讨听觉通路上神经元的电压门控性离子通道与耳鸣的关系。

The changes of signal intensity were synchonous. However, there was no significant change in other subcortex regions.

上述4个区域信号的抑制变化过程同步；皮层下其他区域包括海马基底节区未引出激活点。

Results ICT was detected in pons、cerebellum、basal ganglia、thalamus and subcortex.

结果 ICT可见于脑桥、小脑、基底节区、丘脑及皮层下。

And these are called subcortical structures because they're below the cortex.

这些被称为皮层下结构，因为他们是低于大脑皮层。

Objective TO investigate local cerebral blood flow changes in patients with depression after a subcortical stroke.

目的 研究皮层下梗死伴抑郁患者的局部脑血流变化。

17 patients with a single subcortical lesion were examined with regional cerebral blood flow 99mTc-SPECT imaging.

对17名单一皮层下梗死病灶的卒中患者进行99mTc-SPECT脑血流灌注显象。

That lipoxygenase activity markedly increased during the aerly phase of endoclermal suberization was associated with triggering of suberization.

在低光强和暗中，脂肪氧化酶在内皮层栓化前期活性显著增加，可能与栓化作用的启动有关，而高光强下LOX始终处在较低水平。

RESULTS: Four hours after operation, rats injected with bletilla particles developed temporary conscious disturbance, and sustained hemiparesis of contralateral limbs with spontaneous circling behavior. Ischemia or infarction was found obviously in the cortex of parietal, frontal lobes and basal nuclei of the right cerebral hemisphere, where the neurons characterized with vague outlines, pyknosis and necrosis of neuron nuclei were recognized as well. But hemiparesis and spontaneous circling behavior only lasted for 12 h after embolization with bletilla gum.

结果：白芨微粒组大鼠术后4 h内呈现意识障碍，持续性对侧肢体轻度偏瘫及环转，TTC染色显示右侧大脑半球额叶、顶叶皮层和基底核附近局灶性缺血或梗塞，光学显微镜下可见缺血区脑组织水肿或坏死，神经元轮廓模糊，核固缩或裂解等；白芨胶组仅在术后术后1 h内有轻度意识障碍，12 h内出现对侧肢体行动障碍，但未见明显病理改变。

objective to study mri diagnostic value on multiple sclerosis.methods mri examination data of 31 patients with multiple sclerosis were analysised retrospectively.results total 184 lesions were detectived in 31 patients.most lesions were located on white watter area beside the lateral ventricle,and a few lesions were located on the spinal cord,cerebellum,brain stem and corpus callosum.the shape of lesion can be circle or ellipse.the lesion showed as slightly long t1 and long t2 signal.the acute stage lesions can have enhancement.conclusions ms have characteristic findings on mri image.mri can show the patholoic changes,and provide strong evidence for clinic diagnosis of multiple sclerosis.

摘 要］目的：探讨多发性硬化（muliplle sclerosis，ms）的mri特征表现及其诊断价值。方法：回顾分析31例临床诊断为ms患者的mri检查资料。结果：31例共发现病灶184个，病灶于侧脑室旁白质区、半卵圆中心及皮层下区最多见，其次见于脊髓小脑、脑干及胼胝体，部分可见视神经受累，病灶呈卵圆形或圆形稍长t1、长t2信号，矢状位像见病灶与侧脑室垂直，急性病灶增强扫描有的可呈结节状、环状或斑点状强化。结论：在mri图像上ms有特征性表现，mri能反应ms病理变化，为临床诊断ms提供可靠依据。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。