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Malignant tumor cells and their surrounding cells can secret TGF-β1, which can upregnlate the expressions of VEOF and MMP9, and promote the invasion and metastasis of neoplasms. TGIF is an inhibitor of TGF-β1 signaling pathway.

肿瘤细胞及其周围的间质细胞能分泌TGF-β1,TGF-β1能通过下游信号分子smad2和smad3调节VEGF和MMP9的表达,促进肿瘤的浸润与转移。

Do not need to pass too much channel, without upriver pressure, also do not need to give you order downstream, the income of the company comes from your nonstop user.

不需要经过太多渠道,没有上游的压力,也不需要下游给你订单,公司的收入就来自你的直达用户。

The Modern scholors generally regard Dayus watercontrol project as a legend instead of historic factBy the data of uranology,the author firstly demonstrates that there were quite a lot of natural disasters about 4000 years ago caused by the nine planets in the solar system moved into one line,and among these disasters ,floodwater was the most serious oneSecondly,with the new discoveries of the geographic and archaeological works...

现代学者多将大禹治水视为中国历史上的神话传说。本文先引天文资料证明距今4000年前后确因九星地心会聚引发了各种自然灾害。在这些灾变中,尤以洪水为大。再引地理、考古资料证明此次洪水在黄河下游地区实为距今4000年前后的黄河南北改道,而改道又加剧了洪水泛滥。然后勾稽历史文献,从典籍中寻求黄河改道的线索。

By the vertical integration of paper material, we can provide the more competitive price and better quality of packages.

透过上、下游一贯化的垂直整合,提供了成本的竞争优势;同时控制制造过程中从原料、制程到成品的质量!

Eliminate source of excessive backpressure or water hammer in the system downstream of the device.

B.4 在装置的系统下游内消除过于严重的反压力或水锤现象的根源。

The Schaefer products are primarily used by suppliers for the automobile industry as well as manufacturers of white goods, computers and communication equipment.

施尔弗的产品主要提供给下游汽车行业的供应商,以及家用电器、电脑和通讯设备的厂商。

In the paper,the development of p xylene production technology is introduced briefly.

简要介绍了对二甲苯的生产技术进展,分析了对二甲苯的国内外供需状况、下游产品发展情况以及近期动态,最后展望了对二甲苯的市场前

In 1542,Alvar Cabeza de Vaca and his small band of soldiers guided their boats down a jungle river.It was the Iguassu,which now marks the boundary between Brazil and Argentina.

1542年,阿尔瓦·卡维萨·迪·威卡和他的一小队士兵驾船来到一条丛林河的下游,这就是伊瓜苏河——现在巴西和阿根廷之间的边界河。

The results show that: Near the slot exit, three synthetic jets couple to one jet and move downstream. Two synthetic jets on both sides are limited and rolled by the middle synthetic jet until they merge together into one centrosymmetric synthetic jet.

研究结果表明:三股自耦合射流都在出口附近耦合成一股射流向下游运动,两侧的射流受到中间一股射流的卷吸融合在一起,融合后仍然是一股沿中心线对称的自耦合射流。

The cooling effectiveness of effusion cooling in the regions with holes and downstream the last row of holes on hot side is much higher than that of conventionary film cooling with the same operation conditions.

在热侧面上的气膜孔区及其下游区,致密多孔壁的冷却效果都非常好,比同等条件下常规气膜冷却的效果好得多。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?