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To evaluate the relationship between the levels of hormones of the hypothalamic-pituitary-adrenal axis and the change of the cellular immunity in the patients with cor pulmonal during acute exacerbation. The 36 patients with cor pulmonal were examined.The plasma levels of adrenocorticotrophic hormone.β-endorphin and glucocorticoids and the counts of CD+3、CD+4、CD+8 cells and the CD4CD8 ratio in peripheral blood were analysed during acute exacerbation and stable stage.

为了探讨肺心病急性加重期患者下丘脑-垂体-肾上腺皮质轴激素水平与细胞免疫变化的关系,本研究同步检测了36例肺心病患者急性加重期及缓解期血浆促肾上腺激素、β-内啡肽、糖皮质激素及外周血 T 淋巴细胞亚群的变化,并分析它们之间的相互关系。

Objective: To investigate the role of the dorsal column in the inhibitory effect of somatic afferent inputs on the central pressor response.

目的:探讨脊髓背柱在躯体传入冲动对下丘脑室旁核兴奋所致的心血管反应的抑制作用中的地位。

Significant negative correla- tions between the diencephalon 5-HT or 5-HIAA and gastric ulcer index were observed after 45-min peroid of stress, whereas significant positive correlations between them were observed after 180-min of stress.

侧脑室注射5-HT增加应激后下丘脑CRF含量,血浆皮质酮、〓和〓的水平,PCPA则有相反的结果;在应激180分钟时,间脑5-HT和5-HIAA水平分别与血浆皮质酮、〓呈明显的正相关关系。

The mechanism of SGLFR in treating the rats with asthma under stress is probably to regulate the hyperfunction of HPA axis and the disorder of immuosystem.

疏肝理肺方议决克制应激条件下哮喘大鼠下丘脑垂体肾上腺皮质轴功效的亢进及调治免疫体系的功效,从而起到防治哮喘的作用。

The level of plasma IFNγ was increased while the level of plasma IL4 was decreased in SGLFRtreated group. Conclusion: The mechanism of SGLFR in treating the rats with asthma under stress is probably to regulate the hyperfunction of HPA axis and the disorder of immuosystem.

疏肝理肺方通过抑制应激条件下哮喘大鼠下丘脑垂体肾上腺皮质轴功能的亢进及调节免疫系统的功能,从而起到防治哮喘的作用。

Research suggests that the primary hypothalamic perturbation in the HPA axis in depression might consist of increased numbers of CRF-containing neurons and CRF mRNA in the paraventricular nucleus, which leads to hypersecretion of hypothalamic CRF.

一些研究提示,抑郁症患者HPA轴中下丘脑的原发性功能紊乱包括室旁核中CRF神经元和CRF mRNA数量的增加,这将导致下丘脑CRF的过度分泌。

The results showed that IFN-γ immunoreactive structures widely distributed in CA1,CA2,CA3 and indusium griseum,which indicates IFN-γ have definite influence on physiological function of hippocampus.

IFN-γ与神经系统的关系目前已逐渐引起人们的重视,已有研究表明,在大鼠神经系统的脊神经节、交感神经节、下丘脑乳头体核和中脑背侧被盖内有IFN-γ分布1

The results showed that IFN-γ immunoreactive structures widely distributed in CA1, CA2, CA3 and indusium griseum, which indicates IFN-γ have definite influence on physiological function of hippocampus.

结果表明,IFN-γ免疫反应主要分布于海马CA1、CA2、CA3区,有少量分布于灰被,齿状回。这为海马具有免疫调节功能的观点提供了新的证据。结合文献,推断IFN-γ在海马-下丘脑-垂体-肾上腺的免疫调控中起主要作用。

METHODS: After a single ip dose of trans-T hydrochloride or Ml, the rats were killed by decapitation. A high performance capillary electrophoresis method was used to determine the concentrations of enantiomers of trans-T and Ml in the serum and different brain tissues, including cerebrospinal fluid, cerebral cortex, corpus striatum, hypothalamus, cerebellum, and medulla oblongata.

大鼠ip单剂量的盐酸trans-T或Ml后,采用高效毛细管电泳法测定血清和不同脑组织中trans-T及Ml对映体的浓度,脑组织包括脑脊液、大脑皮层、纹状体、下丘脑、小脑、延髓。

Objective: To study the effect of electroacupuncture of "Dazhui"(GV 14) and "Mingmen"(GV 4) on hypothalamic corticotrophin releasing hormone,plasma adrenocorticotropic hormone,serum cortisol and tumor necrosis factor-α contents in adjuvant arthritis rats.

目的:通过观察电针&大椎&&命门&穴后下丘脑CRH、血浆ACTH、血清Cort、TNF-α含量的关系,分析电针不同穴位对应激相关因子的影响。

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