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Result bFGF immunoreactivity was found in neuron and gli al cell in corte x,hippocampus habenular nucleus,and found in macrophage surrounding hematoma; Ln immunoreactivity was found in neurons,glial cells and blood vessles in front a l cortex,hippocampus,thalamus hypothalamus.

结果 脑出血后脑内bFGF主要在扣带皮质、海马、缰核及其他区域表达,阳性细胞骨折主要有神经哮喘元、神经哮喘胶质、吞噬细胞骨折、室管膜细胞骨折、伸长细胞骨折等;Ln不仅在大脑皮质、海马、缰核、下丘脑等区域的神经哮喘元表达,且在这些区域的神经哮喘胶质细胞骨折也表达,血管也有阳性反应。

Hrs reperfusion following ischemia 30 min (I/R2h group) and 4 hrs reperfusion following ishcemia 30 min (I/R4h group). The changes of NF-kappa B and ICAM-1 in the forebrain cortex, hippocampine cortex and hypothalamus region measured by using immunohistochemical technique were compared among 6 groups.

应用免疫组化法分别检测各组大鼠肝脏TNF-α及脑皮质、海马和下丘脑区NF-κB、ICAM-1的表达情况,应用原位杂交的方法检测肝脏IL-1βmRNA表达情况。

METHODS The animal model was induced by injecting suspension of yeast hypodermically.

方法用酵母混悬液复制发热大鼠模型,采用实时荧光定量聚合酶链反应检测大鼠下丘脑中COX-1、COX-2的mRNA表达的变化。

To explore the influence on the expression of orexin A in the hypothalamus and orexin type 1 receptor (OX1R) in the medulla of neonatal rats after prenatal nicotine exposure, the 20 pregnant rats were divided into 2 groups randomly. Either nicotine (6 mg/kg per day) or normal saline solution (as same volume as nicotine group) was administered into the pregnant rats hypodermically from the fifth day to the end of gestation.

为了观察出生前尼古丁暴露对新生大鼠下丘脑orexin A及延髓内orexin 1型受体(OX1R)表达的影响,本实验将20只雌性成年大鼠随机均分为二组,怀孕后第5 d开始每天分别皮下注射尼古丁6 mg/kg或等量的生理盐水,直至分娩。

ObjectiveTo observe the effect of Yinhuang micro- enema on the content of prostaglandin E2 in the febrile rat hypothalamus and to explore the possible antipyretic mechanism of YHCE. MethodsThe febrile rats modle was established by injecting 20% suspension of yeast hypodermically (10 ml/kg).

目的观察复方银黄微型灌肠剂的解热作用及对发热大鼠下丘脑中前列腺素E2(PGE2)含量的影响,初步探索其解热机制。

PX induces the synthesizing and releasing of CRH by CRHneurons increase, activates HPA axis through hypophyseal portal system, thenmelatonin supplementation can partly reverse the abnormality, which indicates pinealbody is one of the key factors to maintain the structural and functional stablity ofneuroendocrine-immune network

松果体摘除导致大鼠下丘脑室旁核CRH 神经元合成和释放CRH 增加,并通过垂体门脉系统激活整条HPA 轴,而补充外源性褪黑素后能在一定程度上逆转上述异常,表明松果体是神经——内分泌——免疫网络的结构和功能的重要稳定因素之一。

Fr.A adjusts the body temperature through regulating the contents of HSP of hypothalamus in febrile and hypothermal rats.

Fr.A对高、低体温大鼠下丘脑HSP70含量的调节作用是其双向调节体温的机理之一。

SFO stimulation induced stable and significant drinking behavior and Fos protein expression in 8 areas of the forebrain (organum vasculosum of the lamina terminalis, median preoptic nucleus, paraventricular nucleus, supraoptic nucleus, lateral hypothalamic area, perifornical dorsal area, substantia innominata and thalamic reuniens nucleus), and in 3 areas of the hindbrain (area postrema, solitary tract nucleus and lateral parabrachial nucleus).

结果显示,刺激SFO能诱发明显的饮水行为,与此同时,前脑8个部位(终板血管器官、正中视前核、室旁核、视上核、下丘脑外侧区、穹窿周核背侧区、丘脑联合核和无名质)和后脑3个部位(最后区、孤束核和臂旁外侧核)的Fos蛋白表达明显增强。

The animal model of TAO was established by injecting lauric acid into the femoral artery of rat.

用月桂酸注射于大鼠股动脉造成TAO模型,用脉痛宁溶液灌胃后,检测下丘脑、血浆中β-EP、AⅡ的变化,观察痛阈的变化。

In addition, the up-regulated expression of hypothalamic neuropeptide Y and the up-regulated lipopexia could be decreased significantly by acupuncture

针刺治疗肥胖效果显著,且显著降低肥胖大鼠升高的下丘脑NPY含量,减少肥胖大鼠已增加的脂肪蓄积量。

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