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Results In the medium and high dose F0 groups, it was observed that the atrophy and incrassation of seminiferous tubule, decrease of spermatogenesis, hyperplasia of interstitial tissue, especially in high dose groups spermatozoon abnormality and nucleolus concentration in the rats testis after DU ingestion for 14 months. The changes became more severe with the prolongation of DU ingestion. Such changes occurred in filial rats (F1) after DC ingestion for 5 months. In the medium and high dose F0 groups, it was observed that a little atrophy of kidney glomerulus, hyperplasia of interstitial tissue after DC ingestion for 14 months, and kidney glomerulus fibrosis happened after DC ingestion for 20 months, such changes occurred in filial rats (F1) after DC ingestion for 5 months In the medium and high dose F0 groups, splenic germinal center and periarterial lymphatic sheaths were hyperplasia , companies with lymphopoiesis after DC ingestion for 7 months, splenic white pulp became more small and sparse after DC ingestion for 20 months.
结果 F0代的中、高剂量组大鼠摄入贫铀14个月后可见雄性的精曲小管萎缩,管壁增厚呈空虚网状,生精细胞层次减少,间质细胞增生,但仍见有精子生成;高剂量组可见到精子呈异型性改变,细胞核浓缩深染,且随着摄入时间延长改变愈趋明显;F1代大鼠摄入贫铀5个月后就有上述改变且更为严重。F0代中、高剂量组大鼠摄入贫铀14个月后肾小球轻度萎缩,间质增生明显,20个月时肾小球萎缩纤维化;F1代大鼠摄入贫铀5个月后就有上述改变。F0代中、高剂量组摄入贫铀7个月时脾脏生发中心和淋巴鞘增生,淋巴母细胞增生活跃,20个月时脾小体减少,生发中心稀疏;F1代大鼠摄入贫铀早期和晚期有类似改变。F0和F1代高剂量组摄入贫铀早期肝脏有炎症细胞浸润,晚期骨髓有核细胞减少,脂肪细胞增加。
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Results Analysis of the expression of proteins of JAK2 in leukemic blasts, there was no detectable constitutive expression of phosphorylated JAK2 in all the AML samples analyzed; Furthermore, we could detect a constitutive activation of STAT 3 by immunoprecipitation of the targeted protein in primary leukemic blasts from 3 of 11 AML patients without any cytokine treatment; Pretreatment clinical characteristics, and treatment regimens did not differ significantly between patients with and without constitutive STAT3 activity, there was not significant relation between the constitutive activation of STAT3 and the FAB subvariety and chromosome karyotype; However, the 3 patients with constitutive STAT3 activity seemed to have adverse treatment outcome, one did not show remission, the other two patients relapsed shortly after remission; Consistent with the above-mentioned result, leukemic blasts from the 3 samples with constitutive expression of STAT3 showed higher percentage of spontaneous apoptosis and S-phase cells.
在实验研究基础上,本研究进一步运用免疫沉淀和Western Blot印迹方法,检测AML患者原代细胞JAK2和STAT3活化情况,并分析了STAT3活化与AML患者预后有关指标改变的关系。结果我们的初步研究发现,11例AML患者中,有3例呈现STAT3组成型活化(STAT3阳性,下同),无一例呈JAK2组成型活化。上述3例STAT3组成型活化与FAB分型和染色体核型改变未见明显相关性;在此3例患者中,1例未取得缓解,另外2例虽然取得短暂缓解,但均在二个月内复发。上述3例STAT3阳性AML患者S期白血病细胞百分率数值较组高,而凋亡率数值较低。
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We construct a new shape function base on Taylor expansion and the origin of these problems and solve these problems successfully.
从无单元法中出现上述问题的根本原因出发,并利用泰勒展开公式构造出了新的形函数,有效地解决了上述问题。
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At last, the paper gives a case of simulation analysis to prove the rightness and availableness to above theoritical research work.
最后,为了验证上述工作的结论,进行了一个案例仿真分析,证明了上述理论工作的正确性和有效性。
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Finally, a finite element model to TanJin Olympic Stadium is founded and damage is simulated, and the research on damage orientation is carried on using the method forenamed.
最后针对天津市奥林匹克体育场建立有限元模型,模拟损伤产生,应用上述方法进行损伤定位研究,验证了上述损伤定位方法的有效性,成功地对大跨度空间结构的损伤进行了定位。
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Results: The expression of CTGF protein and CTGF mRNA in the nomal and sham operation group is low in the intracytoplasm of Mesangial cells, renaltubular epithelial cells and renal interstitial cells. Compare with sham operation group, the expression of CTGF protein and CTGF mRNA as yellow particulate in the mode group was markedly increased, and the fibrosis of nephridial tissue is obvious. Panaxnotoginseng could significantly decrease the expression of CTGF protein and CTGF mRNA(P.05), and there was no significant difference between Panaxnotoginseng treatment group and Benazepril treatment group.
结果:正常组及假手术组肾小球系膜细胞、肾小管上皮细胞以及肾间质细胞胞浆内有少量CTGF蛋白及其mRNA的黄色颗粒状阳性反应物,模型组上述部位的CTGF蛋白及其mRNA呈强阳性表达,三七总皂苷组上述指标表达较模型组显著减少,有统计学差异(P.05),与阳性药物组比较差异不显著。
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We hereby acknowledge ourselves to be trustees of said property for said bank.
我们在此承认我们是上述银行的上述财产的受托人。
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We hereby acknowledge ourselves to be trustees of the said property for the said bank.
我们在此承认我们是上述银行的上述财产的受托人。
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Such candidate and I hereby withdraw my nomination for the above-named election.
本人是正式获提名为上述选举的候选人,现因拟加上述选举,故撤回本人在该项选举中的提名。
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Company reserves the right to explain the policy and to re-edit,amend and terminate it bases on company's practice situtation.
公司保留对上述制度的解释权,同时有权根据公司实际情况对上述制度的重新修订、更改和终止。
- 推荐网络例句
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Do you know, i need you to come back
你知道吗,我需要你回来
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Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.
1〕 杨银书,王祥生,李德昌。安徽省首次发现嗜群血蜱。
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Chapter Three: Type classification of DE structure in Sino-Tibetan languages.
第三章汉藏语&的&字结构的类型划分。