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E studied expression levels of WAVE1 in six leukemia cell lines (the human Jurkat T leukemia cells, U937 histiocytic lymphoma cells, Burkitts lymphoma cell Raji, acute promyelocytic leukemia cell HL-60, chronic myelogenous leukemia cell K562 and K562/A02) by Western blotting analysis. Levels of WAVE1 expression were high in all six human leukemia cancer cell lines. In contrast, the constitutive expression levels of WAVE1 were noticeably lower in normal human peripheral blood mononuclear cells, or non-blood cancer cell-lines, including human lung A549 cancer cells, Hela cervical cancer cells, MG-63 osteosarcoma cells, CNE2 nasopharyngeal carcinoma cells, human umbilical vein endothelial cell, QSG7701 hepatocarcinoma cells, and WI-38 lung fibroblastoma cells.

AVE1在人类血液肿瘤细胞系(人T细胞白血病细胞系Jurkat、人组织细胞淋巴瘤细胞系U937、人Burkitts淋巴瘤细胞系Raji、人原髓细胞白血病细胞系HL-60、人慢性髓原白血病细胞系K562和K562/A02)中高表达,在非血液肿瘤细胞系(人肺腺癌细胞系A549、人宫颈癌细胞系Hela、人成骨肉瘤细胞系MG-63、人鼻咽癌细胞系CNE2、人脐静脉内皮细胞系HUVEC、人肺成纤维细胞系WI-38、人肝上皮细胞系QSG7701)以及正常人外周血单个核细胞中低表达或不表达。

The plasticity of NSCs was detected by the differentiating test. HESCs were induced into dopaminergic neurons by means of adding Sonic Hedgehog Peptide and fibroblast growth factor eight (FGF8) early under the condition of mocked microenvironment and different development stage of dopaminergic neurons in vivo ,meanwhile made comparison with traditional method . The marker of dopaminergic neurons was tested by immunocytochemistry and RT-PCR, the content of dopamine and its derivation homovanillic acid were measured by HPLC-ECD.

模拟体内多巴胺神经元分化发育的不同阶段及微环境,采用早期添加音猥因子及成纤维细胞生长因子-8(FGF8)的方法,诱导hESCs定向生成多巴胺能神经元,并与传统的诱导方法相比较,免疫荧光细胞化学和RT-PCR法检测多巴胺能神经元的标志,高效液相色谱法检测诱导后细胞及细胞培养上清液中多巴胺及其代谢产物高香草酸的含量。

Results CsA clearly decreased creatinine clearance and increased urinary excretion of N-acetyl-β-D-glucosaminidase in rats as compared with those in the vehicle group. Morphologic changes consisted of vacuolization of tubular cell, expansion of the interstitium and interstitial fibrosis, hyalinization of afferent arterioles. Severity of the injury was related to the dosage of CsA. Striped interstitial fibrosis and arteriolopathy were more severe in the rats treated with CsA and low-salt diet than with CsA and normal diet.

结果 用CsA的大鼠出现尿量增多、内生肌酐清除率下降、尿N-乙酰-β-D-氨基葡萄糖苷酶排泄增多等;病理上表现为不同程度的细胞浊肿、空泡变性及灶性分布的间质纤维化和小动脉病变,随CsA剂量的增加,病变呈加重趋势;结合低钠饮食,CsA慢性肾毒性病变明显加重。

On the basis of induced fibrillation theory, a mathematical model is developed to conduct a computer two-dimensional simulation under the consideration of short range repel and hydrokinetic obstruction.

在场致纤维理论基础上,考察短距离排斥力和流体动力学阻力,建立了基本模型,并对电流变效应进行二维计算机仿真分析;以库仑定律为理论基础,对电流变效应进行了三维计算机仿真分析;详细讨论了电流变体结构参数及外加电场对电流变体场致成链状况的影响。

Based on the deterioration mechanism of corrosive medium, a lot of polymer such as ternary-polymer, adding-felt addition, hydrophobe and polypropylene fiber were added to enhance the performance of anti-corrosion, anti-penetration, conglutination and anti-cracking of original cementious material. The microstrure of cementious material was changed from the simplex hydration product of cement to the superposition structure of the hydrolysate of polymer and the hydration product of cement. A lot of the corrosive ions were prevented from the interior of concrete by this stable structure. The results of tryout indicated that the mending material has the good effect at the corrosion form of corrosive medium.

根据介质腐蚀形式的劣化机理,该文以提高修补材料耐腐蚀性能、抗渗透性能、粘结性能和抗裂性能为出发点,采用添加有机硅改性三元共聚物、增粘剂、孔隙憎水剂等多种聚合物和聚丙烯纤维对原水泥基材料进行改性,使得修补材料的内部微观结构从单纯的水泥水化产物转变成聚合物和水泥水化产物叠合的空间网状结构,这种稳定的结构能有效抵抗各种介质离子的侵蚀,在实际工程上的试用也显示出新修补材料良好的使用效果。

As PAN contains a large amount of hydrophobic radicals,the polyacrylonitrile fiber has poor hydroscopic property and is easy to generate static,which not only affect the processing behavior of polyacrylonitrile fiber but also decrease the wear behavior of fabrics.

睛纶是合成纤维主要品种之一,有&合成羊毛&之称。由于原料聚丙烯睛中含有大量的疏水性基团,睛纶的吸湿性较差,极易产生静电。静电会导致纤维缠绕或堵塞机件,影响织造过程的顺利进行;静电荷在服装上积聚容易使穿着者产生不适感,降低了睛纶纺织品的服用性能。

An MTrP is a hyperirritable spot in a taut band of skeletal muscle fibers with characteristics related to central sensitization in the spinal cord.

肌筋膜激痛点是骨骼肌肉纤维里紧绷肌带上的过度激活点,伴随著与脊髓里中枢性敏感化有相关联的特徵。

The PGFs, for example, basic fibroblast growth factor and transforming growth factor-β〓, mediated the stromal-epithelial interaction through paracrine and autocrine, directly controled the growth, differentiation and apoptosis of prostatic cells and played an important role during the process of BPH. In the present study, the expression of bFGF and TGFβ〓 in normal and hyperplasic prostate were determined with immunohistochemistry and in situ hybridization.

多肽生长因子,如碱性成纤维细胞生长因子和转化生长因子(TGF-β1)以旁分泌和自分泌的方式介导间质-上皮相互作用,直接调控前列腺细胞的生长、分化和凋亡,在BPH发病过程中发挥着重要作用。

The fibroblasts of supra interspinous ligament of AS were cultured in vitro and the cells were observed by microscope after histochemical staning.

采用细胞培养法对AS棘上棘间韧带成纤维细胞进行体外培养,显微观察和组化染色特等。

The result suggested that IPE might produce some substance which could inhibit proliferation of fibroblasts and thus favor the filtering effect of the iridencleisis operation.

实验结果提示虹膜色素上皮细胞对成纤维细胞的调制作用可能有利于抗青光眼手术滤过道的维持,并可以部分的解释虹膜嵌顿术的机理。

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