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The changes included that the protrusions on the cell surface diminished, myofilaments and pinosomes in the myoepithelial cells of grade Ⅱ,Ⅲ atypical hyperplasia decreased, and the irregularity of the nuclear morphosis and the increase of nuclear heterochromosome were found.

乳腺不典型增生时肌上皮细胞数目增多,排列紊乱,电镜下可见:①细胞表面的棒状突起消失;②Ⅱ、Ⅲ级不典型增生时胞浆内的肌微丝和吞饮小泡减少;③细胞核增大,不规则,异染色质增多。

Under light microscope, on H-E stain section, four types cells can be distinguish: cells with weak basophilic fibrillar elements; cells with acidophilic granular substance; cells with strong basophilic fibrillar elements and ciliated cells. In the basal lamina region under gland epithelium, there are a few connective tissue; Surface view of the hypobranchial gland could be see by scanning electron microscope, there are cilia and different kinds of secretions distributed. Ultrastructure of the hypobranchial gland could be understand by transmission electron microscope, supporting cells, sensory cells and seven types gland cell were observed to form the glandular epithelium; cells with much rough endoplasmic reticulum,smooth muscle fiber and nerve endings were found beneath glandular epithelium, among basal lamina region.

光镜下H-E染色切片中腺上皮区仅可以区分出四种类型的细胞:弱嗜碱性纤维样细胞、强嗜碱性纤维样细胞、嗜酸性颗粒分泌细胞和纤毛细胞等;腺上皮下的基底膜区有少量结缔组织存在;扫描电镜下可以观察到鳃下腺表面的纤毛及腺细胞的分泌物等情况;透射电镜下观察到腺上皮中有支持细胞、感觉细胞和7种类型的腺细胞;近基底膜区观察到富含粗面内质网的细胞;基底膜间为薄层疏松结缔组织,内含肌细胞及神经末梢等结构。

The principal microscopic lesions were the inflammation,and necrosis of the mucoase membranes of proventriculus,degeneration of the parenchymatous cells o...

主要的组织学变化为腺胃粘膜上皮坏死脱落、固有层水肿、有炎性细胞浸润、肌层有淋巴细胞浸润、肌细胞坏死、腺小叶腺细胞坏死、核浓缩。

Methods Dietary-induced hyperlipidemia were induced in female SD rats by given 4% cholesterol and 1% cholic acid diet for 16 weeks.

用含4%胆固醇和1%胆酸钠的高脂饲料饲喂大鼠建立高脂模型,观察大鼠血脂、24h尿蛋白、血肌酥和肾小管间质病理改变,免疫组化法检测肾小管上皮细胞巢蛋白和α-平滑肌肌动蛋白表达。

In small intestine,the villous epithelial cells,Paneth cells and parasympathetic ganglion cells in myenteric plexus show GnRHR immunoreactivity.

三段小肠绒毛上皮细胞、潘氏细胞、十二指肠腺上皮细胞以及小肠肌间神经丛副交感神经节细胞,均呈较强的GnRH受体免疫反应性。

Methods SP immunohistochemistry was used to detect actin expression in normal breast tissue, grade Ⅰ,Ⅱ and Ⅲ atypical hyperplasia and breast cancer. Electromicroscopy was used to observe the changes of ultrastructure of myoepithelial cells.

用免疫组化SP法分别检测正常乳腺组织、Ⅰ级一般性增生和Ⅱ级、Ⅲ级不典型增生乳腺组织及乳腺癌组织中肌动蛋白的表达情况,并用电镜观察肌上皮细胞超微结构的变化。

The positive expression rates of actin in grade Ⅲ atypical hyperplasia (70%) and breast cancer(90%) were significantly higher than that in grade Ⅱ atypical hyperplasia(10%), P.01. In mammary atypical hyperplasia, the number of myoepithelial cells increased with disturbed alignment and abnormal ultrastructure.

在上皮细胞中未见表达;而Ⅲ级不典型增生及乳腺癌组织上皮细胞中肌动蛋白表达阳性率分别为70%(7/10)和90%(9/10),明显高于Ⅱ级不典型增生的10%(l/10),P.01。

Results The expression of the Mahoganoid protein and its mRNA was showed by brown staining and observed in the Leydig cells, spermatogonia, primary spermatocytes, spermatids, Sertoli cells, and peritubular myoid cells of testicular tissues and principal cells, basic cells and epithelial cells of epididymal tissues.

结果1。免疫组化法检测Mahoganoid蛋白的实验结果显示的棕色阳性信号可见于各天龄段大鼠睾丸的生精细胞、支持细胞、间质细胞和管周肌样细胞以及附睾输出管的高柱状、低柱状上皮细胞和附睾管的上皮细胞、主细胞、基细胞。其中Mahoganoid蛋白主要表达于胞膜和胞浆。

Objective: To characterize the clinical, laboratory, immunological, image, and pathological features inpatients of dermatomyositis/polymyositis with interstitial lung disease.

目的:研究皮肌炎与多发性肌炎并发间质性肺炎病患在临床、实验室检查、免疫学、影像学、病理学上的特色。

Changes in brain tissue similar to those of newborn in HIE were detected after 2 hours of hypoxia and ischemia.Meanwhile,swelling of kidneys,hemorrhage below encapsules,swellin of tubular epithelial cells,necrosing and falling of a few tubular epithelial cells,and narrowing of tubular lumens were observed.The basement membranes of renal tubules remained normal ...

结果发现新生猪经2小时缺氧缺血后,在脑组织出现类似新生儿HIE病理损害的同时,肾脏出现肿胀,包膜下出血,肾小管上皮细胞肿胀,管腔变窄,少数上皮细胞坏死脱落,肾小管基膜完整,血清尿素氮及肌酐明显升高(P<0.025及P<0.05),表明在HIE状态下新生猪已出现肾脏的病理及功能损害,但损害程度较轻,解除缺氧72小时后,上述损害基本恢复正常。

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