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上皮细胞

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Results of the 621 patients, 388 were identified to have ASCUS, 147 had low-grade squamous intraepithelial lesions, 75 had high-grade squamous intraepithelial lesions and 11 had squamous cell carcinomas.

结果 将细胞学结果与组织学结果作对比分析,细胞学异常的621例样本中ASCUS 388例,低度鳞状上皮内瘤变147例,高度鳞状上皮内瘤变75例,鳞状上皮细胞癌11。

Objective: To investigate amplification of the human telomerase RNA component gene in the cervical exfoliated cells and to explore its value in diagnosis and treatment of cervical intraepithelial neoplasia and malignancy.

目的:研究宫颈脱落细胞中人端粒酶RNA组分基因的表达,探讨其在宫颈上皮内瘤变及鳞状上皮细胞癌诊断中的价值。

Our study includes four aspects. In the first aspect we study several important conditions of porcine oocytes maturation in vitro and oocytes cleavage after parthenogenetic activation and found mNCSU-23+15IU/mlPMSG+20IU/mlHCG+15% PFF+0.57mMcysteine is a good culture condition .When the Cocs are cultured in it ,the maturation rate and oocytes cleavage rate are higher than those of foreign covered. Our result are (86.7±3.35)% and (86.3±4.16)% and the highest report of foreign is(85.7±4.1)%.In the second aspect we study the effect of different chemical activations on development of porcine parthennogenetic embryo and found two best activation method. The first one is that putting the maturation MII oocytes in the 20μmol/L ionomycin for 30 minutes and then putting them in the NCSU-23 condition containing 5μg/mICB and 5mM/L6-DMAP for 3.5 hours, the oocytes cleavage rate and morulae/blastocysts development rate are (76.7±7.6)% and (37.1±6.4)%.The second one is that putting the maturation MII oocytes in the 200μM/L Thimerosal for 20 minutes and then putting them in the NCSU-23 condition containing 8mM DTT for 30 minutes

本研究分为4个部分,第一部分对影响猪卵母细胞体外成熟和孤雌激活后胚胎分裂的几个重要条件进行了比较研究,确立了一种较好的培养方法:与颗粒细胞共培养,找到了一种适合猪卵母细胞体外成熟的培养基:mNCSU-23+15IU/mlPMSG+20IU/mlHCG+15%PFF+0.57mM半胱氨酸,成熟率和分裂率分别为(86.7±3.35)%和(86.3±4.16)%,国外报道的最高成熟率为(85.7±4.1)%;第二部分对猪卵母细胞孤雌激活的化学方法进行了研究,确立了化学激活猪卵母细胞的两种最佳方法:1将成熟的去卵丘颗粒细胞的MII期卵母细胞用20μmol/Lionomycin作用30min,再将卵母细胞培养于含5μg/mlCB和5mM/L 6-DMAP(6-二甲基氨基嘌呤)的NCSU-23培养液中,卵裂率和桑囊胚发育率达到(76.7±7.6)%和(37.1±6.4)%2将成熟的去卵丘颗粒细胞的MII期卵母细胞在200μM/L的Thimerosal中处理20min,再与8mM的DTT共孵育30min,卵裂率和桑/囊胚形成率为(81.0±2.8)%和(39.6±2.7)%;第三部分对孤雌激活胚胎的培养条件进行了研究,确立了一种最佳的胚胎培养条件:在SOF简单培养基中添加颗粒细胞进行前3天的培养,然后转入添加胎牛血清的NCSU—23培养基并和输卵管上皮细胞进行后期的培养,其桑椹胚和囊胚的发育率为(59.5±3.2)%;第四部分研究了IGF-I

. Conclusions:(1) AA-Ⅰ could induce apoptosis of HK-2 and the secretion of FN and TGF-β1 at a range of concentrations. Analysis of their time course and the blocking test indicate that those effects of AA-Ⅰ are partly mediated by TGF-β1.(2) AL-Ⅰ as one metabolite of AA-Ⅰ could induce the direct injury of HK-2, which potency was higher than AA-Ⅰ.

(1)在一定浓度范围内AA-Ⅰ能够导致肾小管上皮细胞凋亡、并诱导FN和TGF-β1分泌,上述事件发生的时相关系分析及抗TGF-β1中和抗体阻断试验结果表明,AA-Ⅰ导致肾小管上皮细胞损伤的作用可能是由TGF-β1所介导的。

NGF positive immunoreactive cells were observed in the airway epithelia of control group. The positive reactivity are located at cell plasm. The NGF positive immunoreactive cells are round or polygonal shape and throughout the whole C〓~T〓 spinal ganglion of control group.

对照组豚鼠气道上皮内可见到含有NGF免疫反应阳性颗粒的上皮细胞,阳性反应物位于胞浆,呈棕褐色。C〓~T〓段脊神经节内,NGF免疫反应阳性细胞遍布整个神经节,多呈大圆形或多角形。

Enteral administration of carbachol can inhibit apoptosis of intestinal epithelial cells in rats after gut I/R injury.

卡巴胆碱能抑制I/R时肠上皮细胞caspase-3表达,增加Bcl-2表达,减少肠上皮细胞的凋亡。

The results suggested the staining of epithelial cells and glands in the cecal mucosawas supposed to be the expresstion of iNOS.

试验结果提示盲肠粘膜上皮细胞和肠腺上皮细胞的着色可能是iNOS被诱导表达的结果。

This review summarizes the signal pathways through which ATP induces anion secretion by the epithelia of the epididymis, as well as its epithelium-dependent modulation of smooth muscle contraction of the vas deferens.

本综述总结了ATP调节附睾上皮细胞阴离子分泌的信号通路,阐述了ATP对依赖于上皮细胞的输精管平滑肌收缩的调节机制,讨论了ATP在男性生殖道中的总体功能和作用。

After observing122samples of leukorrhea we find that the infection rate of epithelia of patients with colpitis is higher than that without colpitis.

通过对122份标本的观察分析,诊断为阴道炎的病人上皮细胞感染率高于般查体者的上皮细胞感染率。

So we can get the conclusion that the various epithelia of the Leukoderma of vulva may have exceptional proliferation activity and Chinese herb may cure the disease through restraining exceptional proliferation activity.

经中药治疗后,ki-67的过度表达减少,结论:外阴白色病变患者各型上皮细胞均可能存在着异常增殖活性,中药可能通过抑制上皮细胞的异常增殖。

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