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Results:(1) Progesterone-treated models showed intact nasal mucosa, regular ciliary lining and inactive glands;(2) Untreated or normal saline treated models showed disrupted mucosa, inverted cilia and massive mucosal infiltration of neutrophils;(3) Smearing of nasal discharge revealed limited vs abundant number of neutrophils in SD models treated with progesterone vs untreated or treated with normal saline.(4) Hoechst stain: significantly fewer apoptotic cells per field were found in progesterone-treated models (1.583 ± 0.28) compared with untreated or normal saline treated models (2.85 ± 0.285 and 4.8 ± 0.715, respectively).

结果:(1)用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮完整,纤毛整齐,腺体开放不多;(2)用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔黏膜上皮纤毛倒伏,上皮结构散乱,上皮层大量中性粒细胞浸润;(3)鼻腔分泌物涂片示黄体酮滴鼻液治疗的SD大鼠有少许中性粒细胞,而用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔分泌物含有大量中性粒细胞;(4)Hoechst染色:用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮凋亡细胞数[(1.583±0.28)/视野]明显少于用或不用生理盐水滴鼻液治疗的SD大鼠[分别是(2.85±0.285)/视野和(4.8±0.715)/视野]。

The respiratory portion begins when an air sac first arise which appears as an outpocketing of the bronchiole.

呼吸性细支气管:壁上有散在的肺泡开口,上皮为单层立方上皮,在肺泡开口处,移行为单层扁平上皮。

We got the result: Bufo Raddei Strauch Tadpole (1) Bufo Raddei Strauch Tadpole was capable of lens regeneration, which originated from the epithelial cells at iris dorsal margin by dipigmentation.(2) Dipigmentation of Bufo Raddei Strauch by two methods: one was licked up by amoebocyte, the other one was flowed from the pigment cells.(3) In the lens regeneration cells of Bufo Raddei Strauch profiles of the mitochondria became complicated ribosome manifold, and the endoplasmic reticulum was cisternal dilation. During the process of deferentiation of lens fiber the cell nucleolus became little and chromatin shrinked.(4)The crystalline electrophoresis of Bufo Raddei Strauch Tadpole lens regeneration showed that during lens regeneration P-crystalline was expressed earliest then was γ-crystalline and α-crystallin, this result is consistent with newt.

结果表明:花背蟾蜍蝌蚪(1)具有晶状体再生的能力,其晶状体的再生来源于虹膜背缘的上皮细胞;(2)虹膜背缘去色素是转分化的前提,主要有两种方式:一种也是最主要的方式是在晶状体被摘除后虹膜外侧产生巨噬细胞,巨噬细胞吞噬虹膜色素上皮细胞中的色素颗粒;另一种方式是虹膜色素上皮细胞自身释放色素颗粒;(3)电镜观察发现虹膜色素上皮细胞转分化过程中线粒体有明显变化,核糖体增多,粗面内质网增多,晶状体纤维分化过程中细胞核逐渐凝聚;(4)SDS-PAGE电泳发现,花背蟾蜍蝌蚪晶状体再生中相关蛋白表达顺序与有尾类蝾螈相似,蛋白表达顺序依次是β-晶状体蛋白、γ-晶状体蛋白和α-晶状体蛋白,并且后两种蛋白几乎同时表达。

Results of the 621 patients, 388 were identified to have ASCUS, 147 had low-grade squamous intraepithelial lesions, 75 had high-grade squamous intraepithelial lesions and 11 had squamous cell carcinomas.

结果 将细胞学结果与组织学结果作对比分析,细胞学异常的621例样本中ASCUS 388例,低度鳞状上皮内瘤变147例,高度鳞状上皮内瘤变75例,鳞状上皮细胞癌11。

Was presented in 12 cases (24%) by bacterial isolation. By in-situ hybridization, PCV2 signals were chiefly distributed in interstitial and necrotic lesions, and the positive signals could be found in macrophages-like cells and necrotic debris. PRRSV signals were mainly located at interstitial lesions and alveolar wall, and the positive signals could be found in macrophages-like cells and epithelial cells of alveoli. Swine influenza virus could be found in interstitial and necrotizing lesions, and the signals could be found in macrophages-like cells, and epithelial cells of terminal bronchiole and alveoli.

另运用原位杂交法对PCV2、PRRSV及猪流行性感冒病毒进行检测,结果发现PCV2主要分布於PNP的间质及坏死病灶区,并能於肺泡及终末细支气管上皮细胞、巨噬细胞与坏死细胞碎片皆可见有病毒核酸;PRRSV则多分布於间质病灶区及肺泡壁处,能於巨噬细胞与肺泡上皮细胞见到病毒核酸;SIV则存在於间质及坏死病灶区,且能於肺泡及终末细支气管上皮细胞与巨噬细胞见有病毒核酸。

Results ERα immunoreactivity was detected in the nuclei of epithelial cells lining lobules and ducts.The positive cells located in the inner layer of the two epithelial layers in the lobules and intralobular ducts,but in the interlobular ducts the positive cells located in the outer layer.

结果:ERα在小叶上皮细胞和导管上皮细胞的细胞核内检测到,在小叶和小叶内导管分布于上皮细胞的内层,在小叶间导管分布于上皮细胞的外层。

Cribriform epithelial stomata were seen mostly in 1.5-month old rats.

筛状囊上皮孔主要存在于1.5月龄大鼠的松果体囊上皮,是由许多密集排列的囊上皮细胞周边部细胞膜凹陷形成的圆形孔洞,筛孔直径200—500nm;喇叭口状囊上皮孔见于1.5月龄和12月龄大鼠的松果体囊表面,由相邻上皮细胞向松果体内部凹陷,形成圆形或椭圆形开口,孔径1~4脚。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

We report 2 cases of classic vulval intraepithelial neoplasia with collections of cells throughout the full epithelial thickness and within epithelial downgrowths containing intracytoplasmic mucin.

我们报道了2例女性外阴经典型上皮内瘤变,这2例病变的表面上皮全层和向下生长的上皮细胞巢团内可见富含黏液的上皮细胞。

The proliferative capacity of LEC from human had directly relevance to the age of donor(r=-0.996).Conclusions The formation of lens-like spherules is characteristics of LEC lines in the cultured cells.Under identical conditions,the proliferative rate of LEC from bovine and rabbit is fast than that of LEC from human,but dedifferentiation of LEC from bovine and rabbit is easier than that of LEC from human;LEC from the three species exhibit similar limited growth potential.The proliferative rate of LEC from human has a inversely proportion with age.

&晶状体小体&的形成可作为确定晶状体上皮细胞株的一项特征性依据,而体外培养的人、牛、兔晶状体上皮细胞具有相同的有限生长潜能,在相同的条件下,牛、兔晶状体上皮细胞的生长增殖速度比人晶状体上皮细胞快,但易于发生去分化;此外,人晶状体上皮细胞的生长增殖率与年龄密切相关,年龄越小,晶状体上皮细胞的生长增殖速度越快。

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