上皮癌的

Results of the 621 patients, 388 were identified to have ASCUS, 147 had low-grade squamous intraepithelial lesions, 75 had high-grade squamous intraepithelial lesions and 11 had squamous cell carcinomas.

结果 将细胞学结果与组织学结果作对比分析，细胞学异常的621例样本中ASCUS 388例，低度鳞状上皮内瘤变147例，高度鳞状上皮内瘤变75例，鳞状上皮细胞癌11。

Part I Role of glycogen synthase kinase 3 in squamous differentiation induced by cigarette smoke in porcine airway epithelial cell Squamous differentiation of airway epithelium induced by diverse stimuli, such as cigarette smoke, has been thought to be an adaptive response to chronic injury as well as a precancerous lesion of lung squamous carcinoma.

第一部分糖原合成酶激酶3在吸烟诱导的猪气道上皮细胞鳞状分化中的作用研究气道上皮的鳞状细胞化生常见于慢性支气管炎症、致癌剂刺激等，一般被认为是对慢性损伤的一种适应性反应，也是肺鳞癌的癌前病变，其分子机制尚未完全阐明。

The expressions of E-cadherin and α-catenin in specimens of 54 breast carcinomas and 21 normal breast tissues around tumor were measured by immunohistochemical method. Results In normal breast tissues, E-cadherin and α-catenin were expressed on cell membrance of ductal and acinic cells. No abnormal expressions were found in normal breast tissues. The abnormal expression rates of E-cadherin and α-catenin in breast cancer were 51.9% and 63.0% respectively.

结果 21例癌旁正常组织中，上皮钙黏蛋白和α-连接素均主要定位于腺泡或导管上皮细胞膜上，显示了细胞－细胞间交界和细胞轮廓，二者均表达正常；54例乳腺癌组织中上皮钙黏蛋白和α-连接素的异常表达率分别为51.9%和63.0%。

Histological type: of the 25 cases, 14 were endometrioid carcinomas, 2 were clear cell carcinomas, 2 were adenoacanthoma, 1 was serous papillary adenocarcinomas, 6 were mixed epithelium tumor of ovary.

病理类型为子宫内膜样癌14例，透明细胞癌 2例，腺棘癌 2例，浆液性腺癌 1例，混合性卵巢上皮性癌 6例，镜下均可见良性的异位子宫内膜向恶性移行的证据。

The negative correlation was observed between S100A4 expression and Ecad expression (r=-0.385, P.05) CONCLUSION: The correlated expression of S100A4 and Ecad is closely related to the development of epithelial ovarian carcinoma,which is valuable markers in predicting biological behavior and trend of metastasis in epithelial ovarian carcinoma.

S100A4和Ecad的相关表达与上皮性卵巢癌的发生发展关系密切，是判断上皮性卵巢癌生物学行为、预测侵袭转移的重要指标。

Results Although overexpression of P53 protein was not detected in normal eyelid cutaneous epithelium, meibomian gland and mild epithelial dysplasia, the positive rate of P53 increased in degree in moderate and severe dysplasia, carcinoma in situ and invasive tumors, and PCNA labeling index progressively increased too. Overexpression of P53 protein was detected in 30/53 cases of basal cell carcinoma, 16/32 cases of squamous cell carcinoma, 10/17 cases of meibomian gland carcinoma, and the intensity of P53 protein immunostaining increased with the lowering in the degree of histological differentiation.

结果 在正常眼睑皮肤、睑板腺及轻度不典型增生眼睑上皮中，未见P53蛋白表达，而中、重度不典型增生，原位癌，浸润癌中，P53蛋白阳性表达率逐渐增高，其 PCNA指数也有增加趋势。30/53例基底细胞癌(basal cell carcinoma，BCC)、16/32例鳞状细胞癌（squamous cell carcinoma，SCC）、10/17例睑板腺癌中，P53蛋白阳性表达；同时，随着肿瘤组织分化程度的降低，P53蛋白阳性表达程度有逐渐增高的趋势。

Results Although overexpression of P53 protein was not detected in normal eyelid cutaneous epithelium, meibomian gland and mild epithelial dysplasia, the positive rate of P53 increased in degree in moderate and severe dysplasia, carcinoma in situ and invasive tumors, and PCNA labeling index progressively increased too.

结果 在正常眼睑皮肤、睑板腺及轻度不典型增生眼睑上皮中，未见 P53蛋白表达，而中、重度不典型增生，原位癌，浸润癌中， P53蛋白阳性表达率逐渐增高，其 PCNA指数也有增加趋势。30/53例基底细胞癌(basal cell carcinoma，BCC)、16/32例鳞状细胞癌（squamous cell carcinoma，SCC）、10/17例睑板腺癌中， P53蛋白阳性表达；同时，随着肿瘤组织分化程度的降低， P53蛋白阳性表达程度有逐渐增高的趋势。

During the surgery, the lesion was found to be a solid tumor. A surgical wedge biopsy was done and purulent dark yellow fluid was drained from the center of the mass. Histologically, there was a solid pattern of rhabdoid and anaplastic round or oval cells haphazardly arranged with poor differentiation. Immunohistochemical staining was positive for vimentin, a mesenchymal marker; the reticulin staining was consistent with carcinoma.

我们实施了手术切片及肿瘤中心脓状物引流，病理组织学上，我们发现了不规则或未分化的横纹状、圆形及椭圆形细胞；免疫组织染色上，细胞广泛的对非上皮标记vimentin呈阳性反应、且其reticulin染色呈现出腺癌的形式；肉瘤及腺癌的特色皆可在切片中看到，所以我们的诊断是类肉瘤性线癌。

FN have barrier action to tumor cell.Lower or absence of FN expression may play a role to judge prognosis in epithelial carcinoma ovary.Positive of FN expression symptomatize good prognosis in epithelial carcinoma of ovary.

FN对肿瘤细胞有屏障作用，FN表达降低或缺失可作为判定上皮性卵巢癌预后的指标之一，上皮性卵巢癌FN阳性表达是预后较好的指标之一。

In second-line drugs for the treatment of recurrent epithelial ovarian cancer,liposomal doxorubicin is more effective and well tolerated.

脂质体阿霉素在复发性卵巢上皮性癌二线化疗药物中有较高的疗效优势，且具有更好的安全性和可耐受性，楷莱可作为复发性卵巢上皮性癌非铂类化疗的理想选择。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。