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In conclusion, accurate diagnosis and aggressive treatment play an important role in the management of small cell carcinoma of the uterine cervix.

正确的诊断和积极的治疗在子宫颈的小细胞上皮癌的处置上扮演重要的角色。

To study the effect of therapeutic factors to prognosis for advanced epithelial ovarian carcinoma.

探讨晚期卵巢上皮癌的综合治疗因素对预后的影响。

Objective:To observe the short term effect of preoperative inductive combined chemotherapy with high dose of cisplatin in the treatment of oral squamous carcinoma and acinic epithelioma.

目的:研究应用以大剂量顺铂为主联合术前诱导化疗治疗口腔颌面部鳞癌和腺上皮癌的近期疗效和安全性。

Results: The short term curative rate of VCP in the cases with oral squamous carcinomas was 83.9%,that of VC5-Fu in those with acinic epithelioma was 63.9%.

结果:VCP方案治疗56例鳞癌的近期有效率为83.9%,VC5-Fu方案治疗36例腺上皮癌的近期有效率为63.9%。

Results 1.VEGF-C expression and MVD in epithelial ovarian carcinoma were higher than those in normal ovarian tissue (P.05),TSP-1 expression were lower than those in normal ovarian tissue (P.05);2.In epithelial ovarian carcinoma tissue,VEGF-C expression and MVD increasing according to progression of the FIGO phase but TSP-1 expression decreasing according to progression of the FIGO phase.

结果 卵巢上皮癌中VEGF-C表达及MVD均明显高于正常卵巢组织(P.05),TSP-1表达低于正常卵巢组织(P.05);卵巢上皮癌组织中,VEGF-C表达及MVD随国际妇产科联盟分期的进展而增高(P.05),TSP-1表达随FIGO分期的进展而降低(P.05)。

Objective To evaluate the efficacy and toxicity paclitaxel liposome and carboplatin in the treatment of advanced epithelial ovaria cancer.

目的研究紫杉醇脂质体联合卡铂方案化疗治疗晚期卵巢上皮癌的临床疗效和毒副作用。

By in situ hybridization, 53BP2 mRNA expression is revealed in tumor cell nests of NPC paraffin sections. The strong positive particles localize in the nuclei of tumor cells; but slight positive signals are also found in tissue cells of chronic nasopharyngitis and connective tissue, such as lymphocytes and smooth muscle cells; There are also positive signals in the nuclei of hyperplastic squamous epithelial cells. However, 53BP1 mRNA expression is not found in nuclei of tumor cells, tissues of chronic nasopharyngitis and connective tissue.

原位杂交结果显示,石蜡切片的鼻咽癌癌巢内,可见53BP2的强阳性表达信号,信号呈紫色颗粒状分布于胞核,核仁清晰可见;而在相同条件下,在慢性鼻咽炎组织和癌旁上皮的结缔组织,也可见弱表达信号,如淋巴细胞和平滑肌细胞;在增生的鳞状上皮细胞的核内,可找到强阳性信号。53BP1在鼻咽癌、慢性鼻咽炎组织和癌旁上皮的结缔组织切片上,均无表达信号。

The results suggest the expression of Nm23-〓 Protein is more often seen in the cases of adenosis with atypical hyperplasia than in the cases of carcinoma, the expression of Nm23-〓 might be a marker of adenosis with atypical hyperplasia in cases of FCD; Lower level of Nm23-〓 suggests in had a high metastatic potentiality in breast cancer.

在浸润性导管癌组中,有腋窝淋巴结转移组的Nm23-〓含量显著低于无液窝淋巴结转移组。结果提示:Nm23-〓蛋白在不典型增生上皮中的表达比癌组织更常见,Nm23-〓蛋白过度表达可能是乳腺上皮不典型增生的一个特征;在乳腺癌病例中,Nm23-〓蛋白表达与腋窝淋巴结状态有关。

We evaluated 350 tumors: 136 ES, including 64 conventional ES, 64 proximal-type ES, and 8 with hybrid features of conventional and proximal-type ES; 54 metastatic carcinomas (22 from lung, 6 breast, 6 stomach, 5 colorectum, 5 kidney, 5 prostate, 5 pancreas); 12 metastatic testicular embryonal carcinomas; 20 metastatic melanomas; 20 epithelioid mesotheliomas; 20 epithelioid angiosarcomas; 10 epithelioid hemangioendotheliomas; 24 epithelioid malignant peripheral nerve sheath tumors; 22 myoepithelial carcinomas of soft tissue; 7 anaplastic large cell lymphomas; 5 histiocytic sarcomas; and 10 control MRT of infancy (4 brain, 3 liver, 2 soft tissue, 1 kidney).

我们总共研究了350例肿瘤:136例ES,其中包括64例寻常型ES、64例近端型ES和8例混有前两型特征的混合型ES;54例转移癌(22例来自肺、6例来自乳腺、6例来自胃、5例来自结直肠、5例来着肾、5例来着前列腺、5例来着胰腺);12例转移性睾丸胚胎性癌;20例转移性黑色素瘤;20例上皮样间皮瘤;20例上皮样血管肉瘤;10例上皮样血管内皮瘤;24例上皮样恶性外周神经鞘膜瘤;22例软组织的肌上皮癌;7例间变性大细胞淋巴瘤;5例组织细胞肉瘤;10例作为对照的婴幼儿MRT(4例位于脑、3例位于肝、2例位于软组织、1例位于肾)。

Methods 200mL fresh midpiece urina sample was collected from each of the 53 patients of transitional cell carcinoma of bladder, 20 patients of other uropoiesis disease, and 10 healthy volunteers, expression of Survivin was detected by nested RT-PCR. Voided urine cytology and cystoscopy were also conducted.

留取53例膀胱移行上皮癌、20例泌尿系其他疾病患者及10例健康志愿者新鲜中段晨尿200mL,对53例膀胱移行上皮癌患者术后癌组织,用巢式逆转录聚合酶链反应(nested RT-PCR)检测Survivin的表达,同时行尿脱落细胞学检查及膀胱镜取材病检。

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