上皮癌

By in situ hybridization, 53BP2 mRNA expression is revealed in tumor cell nests of NPC paraffin sections. The strong positive particles localize in the nuclei of tumor cells; but slight positive signals are also found in tissue cells of chronic nasopharyngitis and connective tissue, such as lymphocytes and smooth muscle cells; There are also positive signals in the nuclei of hyperplastic squamous epithelial cells. However, 53BP1 mRNA expression is not found in nuclei of tumor cells, tissues of chronic nasopharyngitis and connective tissue.

原位杂交结果显示，石蜡切片的鼻咽癌癌巢内，可见53BP2的强阳性表达信号，信号呈紫色颗粒状分布于胞核，核仁清晰可见；而在相同条件下，在慢性鼻咽炎组织和癌旁上皮的结缔组织，也可见弱表达信号，如淋巴细胞和平滑肌细胞；在增生的鳞状上皮细胞的核内，可找到强阳性信号。53BP1在鼻咽癌、慢性鼻咽炎组织和癌旁上皮的结缔组织切片上，均无表达信号。

Methods A case of spindle cell myoepithelial carcinoma of the submaxillary salivary gland with radical neck dissection was examined with light microsecopy and immunohistochemistry,and related literatures were reviewed.

方法对1例颌下腺梭形细胞肌上皮癌及颈清扫淋巴结进行组织形态学和免疫组化观察，并结合文献复习。

Eccrine carcinoma of the sweat gland is rare.

源自汗腺的上皮癌是罕见的。

Results The tissue of 3 cases of ACC in the esophagus was mainly composed of square shape gland epithelial cell and variant myoepithelial cell, mesh shape cavity crack and the tubular, the entity shape arrangement, the cavity crack content basophilia and acidophilia the secretion. There was transmigration of superficial epidermis in 1 case of ACC; All 3 cases were positive of CK, H-CK, P63, S-100 (endochylema /nucleus), EMA, and Bcl-2. Case 3 was positive of CerbB-2 and P53. Case 2 was CD117, AAT, SMA, PAS/AB.

结果 3例食管腺样囊性癌的癌组织主要由立方形腺上皮细胞和变异的肌上皮细胞组成，呈筛孔状腔隙、管状、实体状排列，腔隙内含嗜碱性和嗜伊红分泌物；3例食管腺样囊性癌中例1表面上皮有移行；免疫组化：3例CK、H-CK、P63、S-100、EMA、Bcl-2均，例3 CerBb-2，P53，例2 CD117，AAT、SMA，PAS/AB。

Human epidermoid carcinoma A431 xenograft in nude mice was used to investigate inhibitory effects of the fusion protein in vivo.

体内抑瘤实验表明融合蛋白能够显著抑制人鳞状上皮癌A431裸鼠移植瘤的生长，且毒副作用较小。

The cells at the edge of the basaloid islands tended to show palisading arrangement. Squamous epithelium on the surface of tumor often accompanied with carcinoma in situ or superficial invasive squamous cell carcinoma. Occasionally cancer nets were connected with basement layer of squamous epithelium laying in the surface, and rare squamous cells or glandlike structures were seen in the cancer nests.

但BSC癌细胞分化较低异型性较强，癌巢周围细胞呈栅栏状排列，肿瘤表面鳞状上皮常伴发原位癌或浅表浸润性鳞状细胞癌；偶见癌巢与表面鳞状上皮基底层相连、或偶见癌巢内形成鳞状细胞，或腺管样结构，这些与ACC不同。

These cancer cells might histogenetically be related to the transitional or metaplastic epithelium of prostate according to morphological analysis,(2) Mucinous adenocarcinoma, Xanthomatous carcinoma, ductal carcinoma, medullary carcinoma, endometrioid carcinoma, papillary carcinoma and signet-ring cell carcinoma were positive for PSA and 35βH11, these carcinomas might histogenetically be related to prostatic secretory epithelium,(3) Prostatic carcinoid showed positive to PSA, 35βH11, NSE and CgA, corresponded with endocrine cell originator,(4) Small cell carcinoma were negative for PSA, 35βH11, NSE and CgA, whether or not it originates from endocrine cells, storage cells or basal cell of prostate had yet to be proved,(5) 34βE12 marking was negative in cancerous areas of 27 cases, and the basal cells were absent in PPTC.

从形态分析，这两种癌可能同源于移行上皮或化生上皮：（2）粘液腺癌、黄色瘤样癌、导管癌、髓样癌、宫内膜样癌、乳头状癌及印戒细胞癌均显PSA及35βH11阳性，提示这几种癌可能来源于分泌上皮，（3）类癌对PSA、35βH11、NSE及CgA均显阳性，符合内分泌细胞来源，（4）小细胞癌无PSA、NSE及CgA表达，对c-erbB-2及35βH11显阳性，是否来源于前列腺内分泌细胞、储备细胞或基细胞有待证实，（5）27例癌区均无34βE12表达，提示PPTC中基细胞缺失。

BACKGROUND: Hilar cholangiocarcinoma is a rare tumor with a poor prognosis.

背景：肝门胆管上皮癌是一种预后不良的极少见的肿瘤。

OBJECTIVE: To review the literature with regard to outcome of surgical management for hilar cholangiocarcinoma.

目的：回顾关于手术治疗肝门胆管上皮癌结果的文献。

Immunohistochemical staning for VEGF-C,VEGFR-3 and CD 31 was performed in epithelial ovarian carcinomas, borderline tumors and benign cystadenomas.

应用免疫组织化学法，检测卵巢上皮癌、交界性肿瘤和良性肿瘤组织 VEGF－C mRNA和蛋白表达、VEGFR－3及 CD 31的表达。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。