上皮下的

Remedial group is in ammonia of armour of weekly profess to convinced butterfly Ling15mg foundation applies Yinaxipu, every periderm chip in is shot 2 times, every time 25mg; contrasts the MTX of same dose applies group profess to convinced jointly medicine of other change illness , pyridine of sulphanilamide of the nitrogen that be like willow or come fluorine rice is special.

治疗组在每周口服甲氨蝶呤15mg基础上联合应用依那西普，每周皮下注射2次，每次25mg；对照组口服相同剂量的MTX联合应用其他改变病情药，如柳氮磺胺吡啶或来氟米特。

After cleaning skin with face cream, dorp proper essence on cotton bud with burette, then coating on acne cyst with the cotton swab, and gently press 1 to 2 minuts, making effective ingredients permeate into the skin.

洁面后，用滴管往棉签上滴适量的精华液，用棉签涂于痘痘及痘印处，并轻压1-2分钟，使有效成分渗入皮下，轻微者每天1 - 2次，严重者每天3 - 4次。

In the prison infirmary, Dr. Sara Tancredi sinks a hypodermic needle into Michael's arm.

在监狱医务室里，医生Sara Tancredi在 Michael的手臂上作皮下注射。

It was the first time that using 〓 cell line and normal immunity inbreed line BalB/c mice as objects to construct the subcutaneous transplanting ovarian cancer model. Histopathological experiment proved that the transplanting tumor was undifferentiated cancer. The ovarian tumor marker 〓 and the epithelial tumor marker 〓 were positive in the transplanting tumors. According to these proofs we thought we had already succeeded in constructing animal tumor model.

本实验首次采用卵巢癌〓细胞系，以正常免疫力的雌性近交系BalB/c小鼠为对象，建立了卵巢癌皮下移植瘤模型，经病理组织学检查证实移植瘤为低分化癌，经免疫组化检测证实移植瘤组织中卵巢肿瘤标志物〓和上皮性肿瘤标志物〓表达阳性，据此我们认为动物肿瘤模型建立成功。

Methods The Streptococcus mitis isolated from patient's throat was shaking cultivated in Bact API 20 culture medium, the supernant fluid of which was precipitated with 20%、40%、60%、80%(NH4)2SO4, respectively. The fast protein liquid chromatography was used for final purification. The finally purified proteins were used to challenge rabbits suboutaneously and the responses of fever, diarrhea and reddening of the ears as well as mucous membranes were monitored.

将分离的缓症链球菌在Bact API 20培养基增菌培养后，所得上清液分别用20%、40%、60%、80%硫酸铵分段盐析，进一步快速蛋白液相色谱系统最终纯化，分别皮下注射新西兰兔观察有否体温升高、耳部及粘膜充血、腹泻等致热性表现。

Firstly,all patients have been excided the upper ductus choledochus,the liver gross duct,left right liver duct besides one centimeter of liver duct that lies upwards the hepatolith.Secondly, we have sutured the excided bile duct, which has been shaped acetabuliform,lifted one part of jejunums,intered non-port one subcuneously,and then inosculated gall with enteron by Roux-en-Y way.Lastly,we have partly excised the ill liver in regular way.Results 26 ones have been follow-up for 1～10 years.The rate is 81 percents,average for 6 years.

32例肝内胆管结石均接受皮下盲袢型胆肠吻合术，其中结石位于右肝7例（22%），左肝9例（28%），两肝均有16例（50%）；结石合并肝胆管狭窄24例（75%），全部病例均切开胆总管上部、肝总管、左右肝管，并切开肝内胆管狭窄部以上1cm肝管，将切开的胆管做必要的缝合，形成碟状，取一段空肠上提，盲袢埋置皮下，再做胆肠Roux-en-Y吻合，病肝做规则性肝部分切除术。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

objectiveto evaluate and explore the reconstruction technique of straddling region reversal flow axial composite auricular island flap with blood-supply from supraorbital artery or supratrochlear artery for repairing large alar defects.methodsfrom may of 2004 to macth of 2008, 6 patients with the lager alar defects were studied.

目的：探讨以眶上动脉或滑车上动脉为供血源的跨区反流轴型耳廓复合组织岛状瓣，修复大面积鼻翼缺损的临床应用特点。方法：从2004年5月～2008年3月间，我科选用游离眶上动脉或滑车上动脉与颞浅动脉额支的吻合支为供血源所营养耳廓复合组织瓣，经皮下隧道转移至鼻翼缺损区，ⅰ期修复6例大面积的鼻翼缺损的患者。

At the end of 8 weeks, subcutaneous teratoma was detected in two nude mice, including 3 layers of tissues: sebaceous gland, fat, glandular organ, glandular epithelium and squamous epithelium. At day 4, embryoid body was found and cells were positive for actin, nestin and keratin.

接种8周末，2只小鼠均形成皮下畸胎瘤，其内存在囊括3个胚层的组织结构，包括皮脂腺、脂肪、腺体及腺上皮、鳞状上皮等。

The control mice were injected subcutaneously with 5mL·kg-1 saline once daily,and the mice of the aging model group,with 5g·kg-1 D-galactose once daily,and the mice of low,middle and high dosage groups of Baishen oral liquid,after their aging models were induc...

空白对照组皮下注射生理盐水，5g.mL-1，1次/天，衰老模型组皮下注射D-半乳糖(5g.k-g 1)，1次/天，各给药组在D-半乳糖致衰老的基础上，不同剂量连续给药42d后，处死，采血，分离血清并测定生化指标。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐