上核

In order to get the aryl alkynyl thio ether, we need to synthesize some important terminal functional compounds. Based on the preceding reaearch of our laboratory, we selected methyl thio methyl phenyl sulfone as nucleophilic reagent to eract with aromatic aldehyde and synthesized successfully a series of methylthio aryl ethynes I_ by"one-pot"reaction .

本论文在大量的文献调研和本实验室过去研究结果的基础上，利用亲核硫试剂甲硫基甲基苯基砜(methylthiomethyl phenyl sulfone， MP-S)与芳香醛的&一锅反应&，成功的合成了一系列甲硫芳炔化合物I_，从而为实现形态各异的芳炔硫醚类分子提供了一个良好的构筑平台。

According to the advance of research of tradescantia ecotoxicology all the world, this paper summarized the advance of research and significance of new problem of Tradescantia micronucleu mechanisms and tradescantia stamen hair mutation mechanisms, and the development of the probe test technology, quantification test technology and tradescantia ecotoxicogenome and so on in order to give a reference to research the tradescantia molecular toxicology.

文章从国内外紫露草生态毒理的研究现状出发，针对紫露草微核产生及雄蕊毛突变机制这类新问题的研究现状及意义，以及探针检测技术、定量检测技术和紫露草的生态毒理基因组学的发展等方面进行综述，为紫露草分子毒理上的研究提供参考。

By using multi-dimensional nuclear magnetic resonance method we have studied the folding mechanism of staphylococcal nuclease in vitro; the tertiary interactions for folding of SNase fragments into native-like conformation; the interaction between SNase N- and C-terminal subunits; the relationship of enzyme activity with folding and dynamic states of SNase; the structural properties of enzyme protein while exert its function. We have studied the internal motions of thermophilic Archaea protein Ssh10b and mechanism of its heat-resistance using the NMR 1H-15N relaxation and H/D exchange methods. We have determined the 3D solution structure of human translationally controlled tumor protein TCTP and the Ca2+-binding site; determined the 3D crystal structure of human mitoNEET, a novel protein from distinct groups of iron-sulfur proteins; determined the 3D solution structure of a novel chromatin protein Cren7. Determination of SNase-DNA and Archaea protein-DNA complex structures are in progress.

运用异核多维核磁共振方法研究了金黄色葡萄球菌酶体外折叠机制，酶蛋白片段体外折叠成类天然溶液三维构象的三级相互作用力，酶蛋白亚基间的相互作用，酶蛋白的折叠以及内运动状态与酶活力的关系，酶蛋白发挥功能时的结构特性；运用NMR的1H-15N 驰豫和H/D交换方法研究了嗜热古菌蛋白质Ssh10b双体结构内运动特性，热稳定性机制；确定了人翻译控制的肿瘤蛋白TCTP蛋白的溶液三维结构及其钙离子的结合部位；确定了一类新的铁硫蛋白家族蛋白人线粒体膜上mitoNEET蛋白的晶体结构；确定了一个新型的染色质蛋白Cren7的溶液三维结构；正在研究金黄色葡萄球菌酶及嗜热古菌蛋白质与DNA复合体的溶液三维结构。

Both iron atoms of the binuclear unit are bridged by one oxy atom and two acetate groups. Each iron atom is also bound to facially - coordinating tridentate IDB ligand with the aliphatic nitrogen donor situated trans to theμ- oxy atom. Each iron centers is in a distorted octahedral symmetry.

每个双核单元的两个铁原子均通过一个氧原子和两个醋酸根连接，每个铁原子同时还与位于桥氧原子对位的三齿配体IDB重脂肪链上氮原子相结合，每个铁中心为一变形八面体结构。

The tripolar structure SST anomalies over the North Atlantic, which also appears at the interannual scale with a spectral peak at 3—4 years, are mainly resulted from the barotropic driving of the NAO like atmospheric forcing, and thermal process plays a dominantrole in this process. When the NAO is strong, the westerly weakens over the midlat itudes; both the sensible and the latent heat flux release from the ocean tend to decrease, which warms the ocean and leads to positive SST anomalies. Over the sub polar region including the Labrador Sea, a stronger NAO is associated with a deeper Icelandic Low; the high latitudes originated colder air then blows over the ocean surface, the air-sea temperature difference become larger, and the se n sible heat flux loss from the ocean increases, which subsequently leads to colder SST anomalies.

分析表明，模式中三核型SST异常的产生，主要来自大气的强迫，NAO增强，中纬度大洋上的西风减弱，海洋感热和潜热通量损失减少，中纬度大洋得到的净热通量增加，导致SST出现正距平；在包括Labrador 海在内的副极地大洋，NAO增强、冰岛低压加深，气旋性环流增强，来自高纬度的冷空气吹过洋面，海气温差加大，大洋的感热通量损失增加，SST降低。

Methods: On the basis of cloning the M-TNF c D NA encoding region,the authors constructed mTNFm,which could potentially expre ss on the c ell surface with a uncleavable type of TNF resulting in deletion of the sequence encoding enzymatic cleavage site of TNF-α-converting enzyme.

在克隆M-TNF cDNA的基础上，删除两型TNF转换酶酶解部位的编码序列，构建出mTNFm并测序验证；建立只表达膜型T N F的真核细胞株。

The underfrequency load shedding scheme is used to stop the frequency decline and restore frequency in case of severe upsets. Based on some basic principles given in the paper, the entire underfrequency load shedding scheme has been achieved in the single-machine system model and then tested in the multi-machine system model.

在UFLS的设计过程中，本文针对现代大型电力系统对频率动态过程的基本要求，提出了一套用于UFLS方案设计和效果分析的基本准则，在此基础上提出了单机模型下的最大可用容量切除法用于UFLS基本级的设计，讨论了恢复级的设计原则并给出了一组设计结果，所得的UFLS方案在多机系统中进行了详细的校核。

The characteristic hyperattenuation on unenhanced CT scans reflects the high nuclear-cytoplasmic ratio seen at histologic analysis.

平扫CT的特征性高密度反应了相应组织学上高核质比。

The cytochemical localization of POD showed that the peroxidase was found in cells ofboth cultivars after inoculation. The activity of POD in resistant cultivar was higher than that innot only the uninoculated controls but also the inoculated susceptible ones and localized morewidely, such as localized in mesophyll cell wall, intercellular spaces, membranes of chloroplastand mitochondrion and vacuolar membrane. Whereas the POD in susceptible cultivar waslocalized mainly in cell walls but little in plasma membrane with a lower range and intensitythan that in resistant cultivar.

对过氧化物酶的细胞定位研究发现，无论抗病杨树还是感病杨树，接种后均发现细胞中有过氧化物酶反应产物，通过分析发现，毛白杨过氧化物酶的活性不仅明显高于未接种的对照，也明显高于接种处理后的北京杨，并且定位更广泛，在细胞壁、细胞间隙、叶绿体膜、线粒体膜及液泡膜上均有大量定位，而北京杨酶反应产物主要分布于细胞壁上，在细胞膜、核膜局部有少量定位，定位范围及强度均小于毛白杨。

She makes the transition to Hollywood without acquiring a single actor's tic, and Mr Baumbach has created a showcase for her refreshing style that is replete with mumblecore fetishes: unmoored characters and dialogue scenes on couches.

波拜克为杰威的清爽风格创造了一个展示的舞台，这是一个充满呢喃核风味的舞台：演员躺在长椅上，没有固定的角色，没有固定的对话场景。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。