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It shows that the FE method of tireanalysis under driving state and the method dealing with large slip frictionalcontact problems are correct and reliable. The properties of tires under steady cornering state are studied with FEmethod and experiment. Based on the presented contact solution algorithm, a FEmethod is carried out to analyze the properties of tire under steady corneringstate via imposing slip-rolling-constraints on tire bead nodes which contact therim, and the modules are programmed. The mechanical properties anddeformation of tire under pure steady cornering state and steadycornering-driving state are analyzed, and the results show good agreement withthe experimental data.

对匀速侧滑条件下轮胎侧偏特性进行了试验研究和有限元分析研究,基于本文提出的大滑动摩擦接触问题求解方法,通过在胎圈和轮辋接触节点上施加侧偏滚动约束,得到了匀速侧滑条件下轮胎侧偏特性有限元分析方法,编制了有限元分析模块;利用本文给出的有限元分析方法,分析了轮胎在匀速纯侧滑和侧滑-纵滑联合工况下受力变形特性,分析了侧偏角和载荷对轮胎侧偏特性的影响。

Results:When unilateral anterior superior iliac spine loaded by transient stress,0-10 ms,stress distributed from posterior superior iliac spine to anterior superior iliac spine,and on the last 10 ms,there were greater stress distribution around cacroiliac joint,acetabulum and pubic branch.When unilateral positive backside of ilium loaded,between 0 ms and 20 ms,stress transmitted along vertical direction of ilium,and after 20 ms,there were greater stress distribution on cacroiliac joint,both pubic branch,ischium branch and acetabulum.

结果:冲击载荷作用于单侧髂前上棘时,0~10ms主要的应力沿髂后上棘到髂前上棘分布,在冲击后期10ms以后,骶髂关节、髋臼和耻骨支都会产生较大的应力分布;作用于单侧髂骨正后方部位时,0~20ms主要的应力沿髂骨纵行传导,应力分布并没有在冲击峰值10ms时达到最大,而是从20ms之后,应力开始向骶髂关节、双侧耻骨支、坐骨支以及髋臼等部位传导并可见到明显的应力分布。

Six cadavers were prepared for necroscopy, operative procedure of ILIF were simulated on L3-S1, and all related important anatomic structure and their relationship were observed and record. ILIF with transpedicle screw fixation were also performed with cage insertion.3. Twelve fresh frozen bovine lumbar functional spinal units were prepared for biomechanical testing. According to the different treatment order, the specimens were devided into 7 groups, which included: 1intact specimens, 2specimens were treated by left unilateral facetectomy and had homolateral anatomical threaded cages inserted, 3 TLIF with homolateral pedicle screw fixation, 4 TLIF with bilateral pedicle screw fixation, 5 specimens had anatomical threaded cages inserted on the left by intertransverse process approach, 6 ILIF with homolateral pedicle screw fixation, 7 ILIF with bilateral pedicle screw fixation.

方法1、对20名正常志愿者L3-S1节段进行CT增强+三维重建检查,在三维重建图形上测量横突长度、上下横突间距、椎间孔外椎间隙高度及斜径,观查横突间区域血管走形特点并测量血管内径,然后进行统计分析及评价。2、采用福尔马林固定尸体标本六具,模拟ILIF手术对L3-S1节段进行操作,观察横突间区域重要结构的位置和毗邻关系,并模拟同侧椎弓根钉和单枚椎间融合器的置入过程,探讨该术式存在的问题并改进。3、采用小牛脊柱运动节段标本12具,依序进行不同处理后分为以下7组:⑴正常对照组CG⑵左侧小关节切除+椎间融合器植入组(TLIF⑶TLIF附加同侧椎弓根钉固定组;⑷TLIF附加双侧椎弓根钉固定组;⑸左侧横突间入路椎间融合器植入组ILIF⑹ILIF附加同侧椎弓根钉固定组;⑺ILIF附加双侧椎弓根钉固定组。

From the UV spectra, it can be found that the aromaticity of acenaphthenyl groups in C_2 gum is the largest. But there are 30 carbon atoms in the conjugated structure of condensed aromatics in C_1 gum and C_3 gum, while 28 carbon atoms in acenaphthenyl groups in C_2 gum.

但是,在C_1胶、C_2胶和C_3胶三者中,C_1胶侧链上的四苯基苯基和C_3胶侧链上的菲式多苯基苯基都含有30个碳原子,而C_2胶侧链上的苊式多苯基苯基含有28个碳原子,比前面二者小2个碳原子,理应其芳香性在三者之中最小,但事实却恰恰相反。

Grouping lesional and homeochronous normal hip to pair, dynamic measuring AI and AI in each age groups of lesional and normal hip on before reduction、after reduction 3rd month、6th month、9th month、12th month, describing the characteristics of acetabular development in each age groups on every observation time-points, comparing the difference of lesional acetabular development with normal acetabular physiological development.

并以患侧髋关节与同期健侧髋关节进行配对分组,动态测量各年龄组患儿患、健侧髋关节在复位前、复位后第3、6、9和12个月时的髋臼指数和髋臼深度与宽度比值AI(D/W,描述各年龄组在各时间观察点上髋臼发育的特点,比较患侧髋臼发育与健侧髋臼生理发育的差异。

The clinical characters of oligodontia concluded from this study are following:(1) There is significant difference that more teeth absent and more existent teeth anomalies in patients of oligodontia/S group than in patients of oligodontia/I group, and the peg-shaped upper lateral incisor is the most frequently affected teeth with shape anomaly.(2) Both of the two groups have no significant differences in number of teeth missing between maxilla and mandible as well as that between left and right side.(3) The distribution of teeth missing is bilateral symmetry in both groups, but the frequency of teeth lost are different: excluding the third molar, in oligodontia/I group, the lower second premolar is the most frequently congenitally missing tooth followed by the upper lateral incisor, while in oligodontia/S group, the most frequently missing teeth are mandibular canine and maxillary lateral incisor. Nevertheless, the first molars are the most stable teeth in both groups.(4) In oligodonita/I group, the mean mesiodistal dimensions of all type of existent teeth are significantly smaller than normal value. It is implied that oligodontia is not an isolated phenomenon, but is related to a complex of other dental changes.

对于口腔多个恒牙先天缺失的临床特点有以下初步结论:(1)综合征型先天缺牙患者较单纯型先天缺牙患者恒牙缺失数目更多,平均分别为23.9个和14.9个,且现存牙齿有更多的形态异常,分别为7/10例(70%)和6/22例(27.3%),其中最常见的是上颌侧切牙畸形;(2)两种类型的多个恒牙先天缺失患者的缺牙数目在上下颌及左右侧之间均无差别;(3)两种类型的多个恒牙先天缺失患者在缺失牙位上均呈对称分布,但在具体牙位上有所差异:不计第三磨牙,单纯型先天缺牙最常缺失的牙位是下颌第二双尖牙、其次为上颌侧切牙;而综合征型先天缺牙最常缺失的牙位是下颌尖牙和上颌侧切牙;无论何种情况,第一磨牙均为牙列中最稳定的牙齿;(4)在单纯型先天缺牙患者中,现存恒牙的牙冠宽度较国人正常值偏小,差异显著,提示牙齿形态与多个牙先天缺失有一定相关性。

Increased expression of PENK mRNA was more marked in the ipsilateral dorsal horn of the spinal cord, especially in lamina Ⅲ-Ⅳ and the contralateral medulla, especially in the gigantocellular reticular nucleus, lateral paragigantocellar reticular nucleus and lateral reticular nucleus.

本实验用原位杂交技术对电针刺激后前脑啡肽mRNA在脊髓和延髓的表达进行了观察,发现给予大鼠单侧后肢电针刺激引起脊髓和延髓中PENK mRNA阳性神经元数显著增加,尤其是同侧脊髓背角各层PENK mRNA的表达,和对侧延髓网状结构如网状巨细胞核α部、网状巨细胞外侧旁核及外侧网状核中的PENK mRNA表达增加,这与脊髓上传的信号由同侧脊髓交叉到对侧脑干的走行方式是一致的。

The periostea of both experimental and control side of the mandibular ramus were taken and prepared, 2 of each 5 rabbits in a group were prepared for HE stain detection and 3 for proliferating cell nuclear antigen immunohistochemical detection.Results:1, The newly formed bone was detected on the lateral aspect of mandibular ramus after periosteal distraction. The bone was shaped like a hill. It looked very low and was full of holes at postoperative day 28. With the time of consolidation period lengthened, the newly formed bone matured gradually. X-ray examination showed the new bone shaped like a hill. The average values of new bone height at postoperative days 28,35,42 and 56 were 1.86 + 0.15mm, 2.29 + 0.29mm,3.19 + 0.13mm and 4.70 + 0.45mm. Histological examination of both HE stain and picricacid-fuchsin stain showed the increase in the number of osteoblasts and the change in the orientation of collagen fibers and bone trabecula. There were no significant differences between newly formed bone and original bone on the lateral aspect of mandibular ramus at postoperative day 56 histologically.2 Compared with the control side, the distracted periostea proliferated obviously under the microscope, and the number of periostealcells increased with satiation of cellular nuclear per unit area. The images of PCNA immunohistochemical stain of periosteum showed that the experimental periosteum proliferated obviously after distraction compared with the control side.

结果:骨膜牵张成骨的实验研究南京医科大学硕{学位论文l、骨膜牵张后,可见下领升支外侧的骨皮质上有新骨形成,新骨呈山峰状凸起,术后第28天的新生骨较低平,多孔隙,随着固定时间的延长,新骨逐渐成熟;下领升支前后向切线位X线投照显示新骨呈山峰样隆起;经测量,术后第28、35、42和56天组平均新生骨厚度分别为x.86士0.15mm、2.29士0.29mm、3.19士0.13mm和4.70 土0.45mm;脱钙骨组织的HE染色和不脱钙骨组织的苦味酸一品红染色的组织学观察均显示了新生骨在成骨细胞数量上的增长,以及胶原纤维和骨小梁排列方向上的变化,术后第56天的新生骨在组织学上与原升支骨组织已无明显区别。2、HE染色显示,与对照组相比较,实验侧骨膜增生明显,细胞间排列紧密,单位面积内骨膜细胞数增多,细胞核饱满;骨膜PCNA 免疫组化染色显示,与对照侧相比较,实验侧骨膜在牵张后出现了明显的增生迹象,PCNA阳性细胞分布紧密,单位面积内阳性细胞数较对照组多,靠近骨表面的骨膜中的阳性细胞数更多而且分布更为紧密。

objective to evaluate efficacy of extracorporeal shock wave lithotripsyfor treating ureteral stones in situ,investigate the cause of higher re-treatment rate.methods total of 687 patients with ureteral stone were received eswl between january 2000 and december 2004,included 455 male(66.2%) and 232 female(33.8%) patients,6 cases have bilateral ureteral calculi,12 cases have unilateral multiple calculi.hence,together 709 ureteral calculi were treated.patients upper ureteral calculi were treated in the supine position,for lower ureteral calculi patients were turned prone.to reduce eswl-induced renal trauma and pain,using lower energy source,adjusted power setting from 9.8 to 13.2kv,limited 1500 shock wavs per one session.no auxiliary procedure were used before eswl.the stone size was measured as the surface area of stone length by stone width on x-ray film.the interval between two treatment sessions was two weeks.results of 709 ureteral calculi,the overall stone free rate was 97.3%(690 calculi),re-treatment rate was 34.1%(292 calculi).according to the performed treatment sessions,one session 467 calculi,the mean stone size 37.27mm2,stone free rate 65.4%(464 calculi).two sessions 138 calculi,the mean stone size 62.48mm2,stone free rate 18.4%(131calculi).three sessions 52 calculi,the mean stone size 79.60mm2,stone free rate 7.1%(50calculi).four sessions 19 calculi,the mean stone size 101.63mm2,stone free rate 2.4%(17calculi).fivesessions 33 calculi,the mean stone size 119.33mm2,stone free rate 3.9%(28 calculi).overall 19 cases(2.7%)turned to other treatment modalities.of 335 upper ureteral calculi,303 achieved stone free (95.8%),re-treatment rate was 38.5%(129 calculi).of 374 lower ureteral calculi,369 achieved stone free(98.7%),re-treatment rate was 30.2%(113 calculi).the re-treatment rate of upper ureteral calculi was higher than lower ureteral calculi(p<0.05,χ2=5.40).the difference of stone-free rate between upper and lower ureteral calculi was no significant(p>0.05,χ2=0.15).conclusion eswl should be considered first line therapy for ureteral stone still.stone burden are the main variable of higher re-treatment rate,upper ureteral stone may moving with respiring during eswl.so efficinet shock wave was decreared,re-treatment rate become higher.

目的 评估体外震波碎石治疗输尿管结石的疗效,探讨再治疗率高的原因及输尿管结石的治疗选择。方法回顾2000年1月~2004年12月间eswl治疗输尿管结石的临床资料687例,男455例(66.2%),女232例(33.8%),平均年龄46.6岁(15~83岁)。有双侧输尿管结石6例,单侧多发性输尿管结石12例(4颗1例,3颗2例,2颗9例),共计输尿管结石709颗(含透光结石13颗)。应用上海爱申公司生产的desunit6030型碎石机,c臂x线球管做结石定位。上段输尿管结石(肾盂输尿管交界处至骶髂关节上缘)取仰卧位,下段输尿管结石(骶髂关节上缘下至输尿管口)取俯卧位。为减少eswl引起的肾损伤和疼痛,应用较低的能量,震波发生器电压从9.8~13.2kv,震波频率1.5s。每次治疗设定为1500次震波。治疗后3天摄腹部平片或b超,以后每隔7日重复检查。假如结石未碎或有残留结石最长径>3mm以上,再次eswl,两次治疗的间隔时间为两周。结石的大小用x线片上的表面积(mm2表示。结果 709颗输尿管结石总的治愈率为97.3%(690颗),再治疗率34.1%(242颗)。其中一次治疗467颗,平均结石大小37.27mm2,治愈464颗(65.4%),3颗改治疗;两次治疗138颗,平均结石大小62.48mm2,治愈131颗(18.5%),7颗改治疗;第1和第2次治疗治愈率(1个月治愈率)为83.8%。3次治疗52颗,平均结石大小79.60mm2,治愈50颗(7.1%),2颗改治疗;4次治疗19颗,平均结石大小101.63mm2,治愈17颗(2.4%),2颗改治疗;5次及5次以上治疗33颗,平均结石大小119.33mm2,治愈28颗(3.9%),5颗改治疗。总计19颗(2.7%)结石改变治疗方式。上段输尿管结石335颗,治愈321颗(95.8%),再治疗129颗(38.5%)。下段输尿管结石374颗,治愈369颗(98.7%),再治疗113颗(30.2%)。经χ2检验,上、下段输尿管结石的再治疗率差异有显著性(χ2=5.40,p<0.05),治愈率差异无显著性(χ2=0.15,p>0.05)。不良反应:血压升高13例(1.9%),震波区域疼痛26例(3.8%),震波进入处皮肤点状淤血33例(4.8%),肉眼血尿128例(18.6%),均于第2、3天自行消失。结论 eswl目前仍是输尿管结石的第一线治疗,结石的大小是再治疗率高的主要因素。结石的位置有影响,上段输尿管结石可随呼吸移动,有效震波次数减少,再治疗率比下段输尿管结石高。eswl前注重病例筛选可降低再治疗率。

The mean height from the inferiormidpoint to the edge of inferior joint line was 4.47±0.77mm , 8 percents of thespeciments had a height of less than 3.5mm , and 33 percents of these had aheight of less than 4.0mm .

侧块后中点至中线的距离18.19±1.38mm,侧块后中点至下关节面的距离 4.47±0.77mm,其中小于3.5mm 的占 8.00%,小于 4.0mm 的占 33.00%,侧块后中点在侧块垂线和侧块轴线方向上至侧块前表面的距离分别为 15.91±1.37mm 和18.72±1.59mm。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

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