三羧基的

For developing an immunoassay for multiple residues of pyrethroid pesticides, the hapten N-2- carbanmoyl-(3"-phenoxyphenyl) methyl 3-(2"-Cldoro-3",3",3"-trifluoropropenyl)-2, 2-dimethylcyclopropane- carboxylate was synthesized from cyanohydrin and 3-(2"-Chloro-3",3",3- trifluoropropenyl)-2, 2-dimethylcyclopropanecarboxylic acid via hydrolysis and esterification. The synthesis of the hapten was foundation of preparaing anti- cyhalothrin polyclonal antibodies.

为了制备对单一拟除虫菊酯高特异性的抗体，以菊酸和氰醇为起始原料，通过水解、酯化反应合成了半抗原N-2-氨甲酰-(3-苯氧基苄基)甲基-3-(2-氯-3，3，3-三氟丙烯基)-2，2-二甲基环丙烷羧酸酯，为进一步制备抗三氟氰菊酯的特异性抗体奠定基础。

Eleven novel 2-alkylthio-5-(5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine-5-yl)-1,3,4-oxadiazole derivatives (5) and six novel 2-alkylthio-5-(5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine-5-yl)-1,3,4-thia- diazole derivatives (8) have been designed and synthesized by using 5-amino-3-ethoxycarbonyl-1H-1,2,4-triazole as a starting material.

以5-氨基－1H-1，2，4-三唑－3-羧酸乙酯为起始原料，设计合成了11个新型的2-取代硫醚－5-（5，7-二甲基－1，2，4-三唑并[1，5-a]嘧啶基）-1，3，4-恶二唑类化合物(5)和6个新型的2-取代硫醚－5-（5，7-二甲基－1，2，4-三唑并[1，5-a]嘧啶基）-1，3，4-噻二唑类化合物(8)。

After esterification, the ethyl-2-chloro-3-phenylpropionate reacts with diethyl malonate under the catalysis of sodium ethylate, and we obtain the corresponding triethyl ester. The-benzylsuccinic acid is formed by the triethyl ester reacting with concentrate hydrochloric acid and taking place hydrolyzation and decarboxylation reaction at the same time. In order to avoid the formation of cinnamic acid, the sodium ethylate and diethyl malonate must be react sufficiently. The course has simple operation, inexpensive materials and better yield.

具体制备工艺为：首先以L-苯丙氨酸为原料采用重氮化方法得到-2-氯-3-苯基丙酸，再经酯化得到-2-氯-3-苯基丙酸乙酯后在乙醇钠催化作用下和丙二酸二乙酯缩合，发生SN2反应，得到相应的三乙酯，然后经水解和脱羧，得到-苄基丁二酸；在实验中乙醇钠要和丙二酸二乙酯充分反应，避免生成肉桂酸乙酯；该过程操作简单，原料便宜，产率较高，总收率可达到26.8%。

Compared with the Epoxy resorcinol-formaldehyde resin pretreatment system and Maleic anhydride pretreatment system developed by Xusigui, the 40% carbolated styrene-butadiene latex system can keep the composite"s properties and reduce the cost of pretreatment and simplify the pretreatment technology; especially to the HST 2073 latex system, the composite"s mechanics properties are improved greatly. Secondly, the composite"s comprehensive properties and interface performance are improved by reinforced with short fiber grafted with rubber in the surface. Thirdly, to simplify the production technology of composite, we add TKM-M and RF-90 as adhesive agent to the composite blended in an internal mixer, so as to the composite can be used to industry widely, then the effect of the amount adhesive agent on the composite"s properties and interface adhesive performance was studied, from the experiments the optimum amount of adhesive agent was deduced.

其中采用特软羧基丁苯胶乳预处理短纤维的方案，降低了预处理成本，相对许泗贵的低分子环氧和马来酸酐体系来说，预处理工艺大大简化了，而材料的力学性能保持良好，尤其是 HST 2073A 胶乳预处理体系，力学性能有较大幅度的提高；第二，通过对尼龙短纤维表面进行接枝橡胶分子链预处理，改善了复合材料的界面粘合性能，复合材料的综合性能也得到了相应的提高；第三，为了简化复合材料的生产工艺，使复合材料的应用得到工业化推广，我们选用TKM—M和RF—90长效增粘剂，直接加入短纤维橡胶复合材料中，采用密炼工艺，探讨了增粘剂的用量对复合材料界面粘合以及性能的影响，得出了增粘剂在复合材料中的最佳用量。

SM6 and SM7 of uncrystal were analyzed through GC-MS, the results showedthat SM6 main contained unsaturated fatty aldehyde with fragrance, i.e.-2,4-decadienal(58%), tetradecanoic acid (55.78%), 2-decenal(50%), Phthalic acid isobutylundecyl ester(47%), 2, 4-Decadienal(41%), 2-Undecenal (31%), 2-Methyl-Z,Z-3, 13-octadecadi-enol(18.84%), and SM7 contained saturation alkanes, i.e. 1, 2-Benzenedicarboxylic acid, butyl cyclohexyl ester(23.90%), Triacontane(22.63%),Nonacosane(21.04%), Heptadecane(18.84%), Octacosane(13.58%). Toxicological experiments were done to insure the pigment safety.

并对紫红丝膜菌色素非晶体部分的黄色油状物SM6和紫色粉末物SM7作了GC-MS分析，结果显示SM6中主要为具有香气成分的不饱和脂肪醛，其中含量较高的依次为：-2，4-癸二烯醛(58％)、十四烷酸(55.78％)、2-癸烯醛(50％)、邻苯二甲酸异丁基十一烷酯(47％)、2，4-癸二烯(41％)、2-十一碳烯醛(31％)、2-甲基-Z，Z-3，13-十八碳二烯酸(18.45％)等；SM7中主要为饱和直链烷烃，其中含量较高的依次为：1，2-苯二羧酸丁基环己酯(23.90％)、三十烷(22.63％)、二十九烷(21.04％)、十七烷(18.84％)、二十八烷(13.58％)。

Based on our intensive studies on the lactonization of oligo/polysialic acids, we proposed for the first time that the lactone-ring formation of oligo/polysialic acids has three stages. We also provided a novel model to explain the conformational changes of oligo/polysialic acids caused by the repulsing forces among the carboxyl groups of sialic acid residues. Our results should provide novel approaches for further investigation of the structural-functional relationships of oligo/polysialic acids.

在对多/寡聚唾液酸内酯化过程进行深入研究的基础上，于国际上率先提出多/寡聚唾液酸内酯的形成具有三个阶段的观点，并首创性地提出了羧基排斥所致多/寡聚唾液酸分子空间构象改变的模型，为深入研究多/寡聚唾液酸结构与功能的关系提供了新生长点。

The fluorescence spectra of 4- 5 '-p-biphenylyloxadiazolyl-2' benzyl ω-p-biphenylyl polymethylene car-boxylate have been determined. The results of experi-ment show that they can form not only intramolecularexciplex but also intermolecular excimer and triplex.

测定了ω-对联苯基多亚甲基羧酸4-[5'-对联苯基〓二唑-2']苄酯的荧光发射光谱，从实验结果得到，它们不但可以形成分子内激基复合物，而且可以形成分子间激基缔合物和三分子激基复合物。

Examples of metal chelating groups include hydroxides especially aryl or heteroaryl hydroxides such as phenolic hydroxides; amines which may be aliphatic aryl or heteroaryl; mercaptans which may be aliphatic aryl or heteroaryl; carboxylic acids which may be aliphatic aryl or heteroaryl; oximes and ketoximines; acetarylamides; hydroxy silanes and silicones; N-containing heterocycles such as imidazoles benzimidazoles triazoles benzotriazoles thiazoles isothiazoles acid anhydrides and more preferably acid groups (especially carboxylic acid groups phosphoric acid groups polyphosphoric acid groups phosphonic acid groups sulphuric acid groups and sulphonic acid groups).

金属螯合组的例子包括氢氧化物，特别是芳基或如酚醛氢氧化物杂氢氧化物；胺可能是脂肪族，芳基或杂；硫醇可能是脂肪族，芳基或杂，这可能是脂肪族，芳基或羧酸杂；肟和ketoximines； acetarylamides；羟基硅烷和有机硅，含N，如咪唑，苯并咪唑类，三唑类，苯并三氮唑，噻唑类，isothiazoles，酸酐杂环，多最好酸组（特别是羧酸团体，磷酸，团体，多聚酸组，膦酸组，硫酸团体和磺酸组）。

In this dissertation, preparation of polysubstituted ethene and heterocyclic compounds based on 2-hydroxyalkyl phenyl selenides andα-phenylselenopropionic acid reagents were further investigated as follow: Firstly, O-ethyl-O-vinyl phosphonates were prepared in a one-pot, two-step transformation by Mitsunobu reaction of 2-hydroxyalkyl phenyl selenides with monoethyl esters of phosphonic acid in the presence of diethyl azodicarboxylate and triphenyl phosphine (PPh3) followed by oxidation-eliminatio...

中文摘要：本文主要进一步探索了2-羟基烷基苯基硒醚、α-苯硒基丙酸试剂在制备多取代乙烯和杂环化合物反应中的应用，具体研究内容和结果如下：一、在偶氮二羧酸乙酯和三苯膦(PPh3)存在下，苯基-2-羟基烷基硒醚和O-乙基膦酸单酯发生Mitsunobu反应，无需分离和纯化反应中间体，直接使用30 %的双氧水进行氧化-消除反应，提供了&两步、一锅&合成O-乙基-O-乙烯基膦酸酯的新方法，该方法反应条件温和，操作简便，产物收率良好(76-82 %)。

Experimental results showed that aerosol created by 1,3,5-trimethylbenzene photooxidation can be classify with five distinct chemical particle classes, the predominant components of these five particles are aromatic aldehyde, phenol, nitrophenol and carboxylic acid compounds.

利用该算法对OH自由基启动1，3，5-三甲苯光氧化形成的二次有机气溶胶单粒子质谱数据进行了聚类分析，在得到的五个聚类中包含了芳香醛、酚类化合物、硝基酚和羧酸等重要的光氧化产物，为研究苯系物光氧化机理提供了新的信息。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。