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Apparent partition coefficient in octanol-water and binding percentage to BSA of ~(153)Sm-NTMP,~(153)Sm-HEDTMP,~(153)Sm-DCTMP,~(153)Sm-EDTMP,~(153)Sm-DTPMP,~(113,117) Sn~m-EDTMP,~(113,117) Sn~m-HEDTMP,~(113,117) Sn~m-DTPMP are measured. The results show that there is a linear relationship between the relative magnitude of the apparent partition coefficient in octanol-watetr and the relative magnitude of the binding percentage to BSA of these ~(153)Sm~(113,117Sn~m complexes.

测定了NTMP,HEDTMPN (羟乙基乙二胺基三亚甲基膦酸,DCTMP(1,2 环己二胺四亚甲基膦酸),EDTMP(乙基二胺基四亚甲基膦酸),DTPMP(二乙基三胺基五亚甲基膦酸)的153Sm配合物以及HEDTMP,EDTMP,DTPMP的113,117Snm配合物在正辛醇水中的表观脂水分配系数和在0 5%牛血清白蛋白水溶液中与BSA的结合率。

Radiography and double fluorochrome labeling were taken. Dogs were sacrifice at 1, 3, 6 months post operation and image analysis were done on undemineralized slices then subject to statistical analysis by SAS software, Version 6. 21. 3. BMSCs in vitro induced and proliferated through complete blood culturing were seeded into tricalcium phosphate , fdDBM and 2 kinds of coralline hydroxyapatite with 200μm and 500μm porosity (C200 and C500) respectively.

将全血培养法体外诱导、扩增培养的BMSCs分别与三磷酸钙(tricalcium phosphate,TCP)、两种孔径的珊瑚羟磷灰石(200μm,500μm)以及制备的fdDBM复合,体外培养4~7日后,进行扫描电镜、组织学观察,并行裸鼠皮下回植,了解包括空白DBM材料在内的5组样本的异位成骨情况,经IMAGER-PRO PLUS软件进行图像分析,并进一步行统计分析。

With the isolated and purified PSP as test materials, the chemical model systems were used to produce and OH. resp. And the scavenging capability of PSP on free radicals, its inhibition effect on pyrogallol autoxidation and the effects of PSP on SOD activity and MDA content in tumor-bearing mice were studied.

方法]以已分离提纯的甘薯多糖为试验材料,利用分别产生氧自由基O2(上标-和羟自由基的化学模型体系,研究甘薯多糖清除舟自由基能力及其对邻苯三酚自氧化的抑制作用和甘薯多糖对荷瘤小鼠SOD活性和丙二醛含量的影响。

It is well known that P450 enzymes in mammals represent products of a supergene family, but the majority of compounds are metabolized by three different P450 families.

现在认为大多数药物是由P450 Ⅰ、Ⅱ、Ⅲ三个家族代谢的。clau对映体的羟化代谢反应是由哪一个家族的亚酶代谢的呢?

The cure reactions of ternarysystem containing poly, poly and HDI isocyanurate, and the effect of the ratio ofPGA/POH on the thermal, mechanical and surface properties of curedresin have also been examined.

本文还研究了聚丙烯酸环氧丙酯、聚丙烯酸羟丙酯和六亚甲基二异氰酸酯三聚体的反应及三元反应体系中PGA/POH的不同比例对交联后树脂的热性能、力学性能及表面性能的影响。

The free radical scavenging effects of Meretrix meretrix hydrolysates prepared with papain,neutral protease and acid protease were investigated.

利用正交实验研究了文蛤蛋白分别经木瓜蛋白酶、中性蛋白酶、酸性蛋白酶作用后酶解物对羟自由基和超氧自由基的清除作用,优化了水解条件,并对最佳清除率下的三种酶解物进行SephadexG50凝胶柱分离,测定酶解物中抗氧化活性肽的分子量分布。

4The Masson trichrome stain can be used for an important method for the observation of the fibrostic cells, The changes of the mast cell could be considered as an assist marker for the observation of the liver fibrogenesis.In addition the concentration of the hepatic hydroxyproline could be used for diagnosis of the hepatic fibrosis. clinical and experimental study.

Masson三色染色可以作为肝纤维化肝硬化组织细胞观察的一种重要方法:肝纤维化过程中,肥大细胞数量的动态变化,可以作为观察肝纤维化变化的一项辅助指标;肝脏羟脯氨酸的浓度变化可以作为肝纤维化的辅助诊断及应用于相关实验的研究。

Based on Fenton reaction and the auto-oxidation of pyrogallol, the anti-radical activity of morinda officinalis how was studied by spectrophotometry. The morinda officinalis how has obvious scavenging effects on hydroxyl radical and superoxide anion radicalO2(superscript - with the efficiency related to concentration of morinda officinalis how.

基於Fenton反应和抑制邻苯三酚自氧化原理,分光光度法测定体系吸光度的变化研究巴戟天抗自由基活性,证明巴戟天对羟自由基及超氧阴离子自由基O2(上标-均有良好的清除作用,清除率与巴戟天的浓度有一定的量效关系。

Release of ferric iron catalyzed the conversion of super oxide and hydrogen peroxide to the more toxic hydroxyl radical which has been shown to be an important mediator of ischemic brain edema.

三价铁释放,促使过氧化物和过氧化氢转化成毒性更大的羟自由基,这是缺血性脑水肿的一种更重要的递质。

The positive peptide cleavage promoted by complex, CuⅡL and the negative response of CuⅡ/dien complex suggest the merely hydroxy pendant in complex have no ability to attack the peptide bond. The synergic carbonyl activation by metal coordination is essential for the cleavage of peptide bond promoted by CuⅡL.

比较相应铜配合物及二乙烯三胺铜配合物的切割性能,提示羟乙基侧臂单独难以实现相邻肽键的切割,高配位数金属中心对肽键羰基的活化与羟基的协同进攻是该类配合物切割多肽的可能机制。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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