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In all those complexes, no matter which conformation IDA assumes (mer- or fac-style), the two 0 atoms of 1N2O are both from carboxylic hydroxyl. However, by comparing the bond length, we can find that O(4) and O(2) atom is from different group in this complex, 0(4) atom from carboxylic hydroxyl, whereas, 0(2) from carboxylic carboxide.

值得注意的是:在这个双核配合物中,我们首次发现一种新颖的配位方式:IDA上与金属离子配位的三齿螯合原子是亚氨N原子、一个羧基上的羟基O原子和另外一个羧基上的羰基O原子。

Results show that intramolecular hydrogen transfer is not favored in view of the energy trend along IHT coordinate in the region such as hypericin's peri region, where two hydrogens of hydroxyl groups bond with a common oxygen of carbonyl group and exists two IHBs in the peri region. However, intramolecular proton transfer often occur in the molecule with hexahydric cycle hydrogen bond, where only one pair of adjacent hydroxyl group and carbonyl group.

此外选择设计了一个具有三个分子内氢键的体系,兼具金丝桃蒽酮和其他苝醌类光敏剂的分子内氢键特点,研究表明两个羟基氢与共同的羰基氧形成的氢键由于存在较高的势垒,很难发生分子内氢传递,即具有金丝桃蒽酮端位结构的分子其分子内氢传递很难发生,而一般的能形成六元环状结构的分子内氢键体系容易发生分子内氢传递。

D limonene was distributed among the culture flasks (200 mg/L). The flasks were incubated at 28oC on a rotary shaker (r/min=120) for 5 days. On completion, the culture broth were successively extracted with EtOAc. The extract was quantitatively measured by gas chromatography mass spectrometry analysis, The results showed that biocatalytic reactions were comprised of oxidation, including hydroxylation and ketonization which occurred at different positions of the D limonene, as well as hydrogenation, hydrolyzation, esterification and cyclic cleavage. These bacteria strains possess the distinctive biocatalytic capacities towards the D limonene. A series of terpenoids, including sesqui , di and tri terpernoids were also observed,which was accounted for D limonene had influence on the metabolites of marine bacteria.

以2216E为培养基,添加200mg/L的柠檬烯,在28℃,以120 r/min摇瓶培养5 d,用乙酸乙酯提取培养液,经GC MS分析其转化产物,结果显示,这些细菌能在柠檬烯的不同位置进行羟基化、羰基化等,并伴随有还原、水解、酯化、开环等反应,但转化能力和转化程度不同;在产物中,还检测到系列结构不同的其它萜类:包括倍半萜、二萜以及三萜等,这些萜类化合物的产生跟柠檬烯的加入有关,说明柠檬烯能影响细菌代谢产物的产生。

Expanded MSCs were induced to differentiate into nerve cells withthree different treatment protocol in the prensent study . On the following day, the medium was replaced with preinduction medium consisting of DMEM, 20% FCS, and 10 ng/ml basic fibroblast growth factor. After 24 h, the preinduction medium was removed, the cells were washed twice with PBS, and neuronal induction medium containing DMEM supplemented with 2% DMSO and200 m bu-tylated hydroxyanisole was added. In later experiments, we used DMEM with 5 mM p - mercaptoethanol or sulfo - glycerine as an alternative neuronal induction medium for the same incubation.

将待诱导分化的MSCs按0.4x10~6/ml接种于事先放置有消毒盖玻片的六孔板内制备细胞爬片,分别采用三种不同的方法诱导第2代至10代的MSCs向神经细胞分化,即方法1先用含bFGF的培养基进行预诱导,之后再用含叔丁基对羟基茴香醚,和二甲亚砜的无血清培养基进行诱导;方法2和方法3用B-巯基乙醇和硫代甘油进行预诱导,然后不同浓度的上述物质进行正式诱导。

The mechanical strength, solubleness and the capability to induce ossification of the materials could be improved obviously when strontium was added, which were formed of hydroxyapatite and tricalcium phosphate.

试验研究证实锶盐具有抗骨吸收和增加骨形成的作用,锶盐可以抑制破骨细胞的活性,促进成骨细胞的活性,促进骨盐的沉积;其与羟基磷灰石和磷酸三钙等复合后,其机械强度、溶解性及诱导成骨能力等特性明显得到改善;锶盐口服有治疗骨质疏松症的作用。

Through cyclic hydrogen bonding with motif formed by coordinated water molecules and coordinated hydroxyl groups of dhbd from adjacent tetranuclear units, these adjacent neighbors are connected to afford a 1D supramolecular chain along axis a, which is further extended via aromatic intercalations and other crystallization water molecules into a 3D structure with channels.

毗邻的四核单元通过配位H2O分子和配位羟基O原子形成的 R 22(8)型环形氢键桥的连接,沿a轴方向构建了四核单元交替相连的一维超分子链;链间籍苯环的π-π堆积作用和晶格水分子氢键链的连接进一步扩展为具有隧道的三维结构。

Adopting compound techniques of inorganic nanometer, sol-gel techniques and ultraviolet absorbers are used to obtain new protective materials of hydroxybenoic ketone, benzotriazole and polyvinyl alcohol for the protection of historical relics .

采用无机纳米复合技术,利用溶胶-凝胶方法的分配交联和紫外线吸收剂的添加等工艺手段,筛选出适于文物保护环境的防紫外线照射,又不影响文物展示效果的羟基苯酮类、苯并三唑类及能有效消除弦光,又不影响观赏效果的聚乙烯醇类新型防护材料,以便用以不同环境下的文物保护工作。

The scavenging effect of polyphenols extracted from grape seeds such as monomers, dimers and trimers on superoxide and hydroxyl radicals is studied with the ESR spin trapping method. The results are comparable with those obtained from chemiluminescence method. It has been proved that polyphenols extracted from grape seeds have a strong scavenging effect on Oxygen free radicals. Probably this is the reason why drinking some grape wine every day is good for one's health.

用ESR自旋捕集技术研究了从葡萄籽分离的单体、二聚体和三聚体等多酚类物质对羟基自由基和超氧阴离子的精除作用,并与化学发光法的测定结果进行了比较,得到了较一致的结果,证明葡萄籽中多酚类物质对氧自由基的确有较好的清除作用,这很可能是喝少量葡萄酒有利于身体健康的原因。

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