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Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome

目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。

Three dimension configuration of helical CT scan increased the sensitivity and showed clearer nodular edge feature. It contributes to reliable diagnosis of lung nodus and might be recommendable to clinical application.

胸部螺旋CT三维重建能提高病变检出率及肿块周边的特征改变,从而有助于肺部结节的诊断可靠性,值得临床推广应用。

Objective: To evaluate the clinical application of three dimension configuration in lung nodus.

目的:探讨肺部结节三维重建的应用价值。

In 1993. We described a 57-year-old female, with a long-standing history of rheumatoid arthritis, presenting with symmetric violaceous to erythematous indurated papules and nodules on her buttock and medial thighs arranging in an arciform fashion for more than three months.

我们在此提出一个长期罹患风湿性关节炎的五十七岁女性,在其臀部与大腿内侧出现对称性的紫红色浸润性丘疹与结节约三个多月。

Objective To investigate whether osteoblasts cultured in vitro can form mineralization nodes. Method The osteoblasts at 1×105/ml,2×105/ml and 5×105 /ml cell density were cultured in the DMEM medium and in the DMEM medium supplemented with β-glycerophosphate sodium and ascorbic acid.

目的 了解体外培养成骨细胞的接量对钙化结节形成的影响方法实验选用了1×105 /ml、2×105个/ml、5×105个/ml三个不同的细胞接种浓度,并且每个浓度组分别给予含β-甘油磷酸钠和维生素C的条件培养液以及常规培养液进行细胞培养。

The third line is called the intertubercular, and runs across between the two rough tubercles, which can be felt on the outer lip of the crest of the ilium about two and a half inches (60 mm) from the anterior superior spine.

第三条线为结节间线,在两粗大的结节间走过,位于髂骨嵴的外唇,离髂前上棘大约2.5寸(60 mm)处。

The characteristic of the treatment by manipulation with acupotomy in tensive position is manipulating the adhesions and contractures of capsule in direction: including the zona of intertubercular sulcus, inferior-acromial and the decocted later part of the capsule, and with hydraulic distension and manipulation. Compared with manipulation maneuver this treatment is less traumatic, short of course of treatment, easy to perform and really an effective procedure to treat the frozen shoulder.

粘连挛缩带紧张位针刀松解治疗方法特点在于针对性地松解肩前结节间沟区、肩峰下和肩关节囊后下部等三处粘连挛缩带,在此基础上配合关节腔内注液扩张和术中术后注重肩肱关系的手法松解,与推拿治疗冻结肩相比,本法明显改善了冻结肩患者的疼痛与功能障碍程度,创伤小,疗程短,见效快,疗效可靠,且中远期随访显示疗效稳定。

A difference in pattern classification on 3D CT was found between benign and malignant SPN. Conclusion: 3D CT can not only stereoscopically demonstrate the abnormal signs of SPN, but can also provide information concerning the anatomic relationship between SPN and adjacent bronchi, vessels and chest wall. Combined 3D with 2D CT, the diagnosis can be improved.

三维重建技术不仅能三维显示SPN的异常表现,而且能显示结节与支气管、血管和胸壁是的解剖关系及形态学特征。3D CT结合2D CT有助于提高诊断准确性,是鉴别SPN良恶性的有效的影像学检查方法。

Activity of alkaline phosphatase and ability of formation for calcifying nodules were determined.

抽取健康成人骨髓组织,用Percoll分离液分离出骨髓中的单个核细胞,在含体积分数为10%小牛血清的高糖DMEM培养液中,置于37℃、含体积分数为5%的CO2湿化空气孵箱中培养,通过传代培养扩增骨髓基质干细胞,传三代时改用含地塞米松、β-甘油磷酸和维生素C的条件培养基培养,用倒置显微镜、HE染色观察增殖和分化情况,并测定碱性磷酸酶活性和钙结节形成能力。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。