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This design wants to design a complete set of three axes five speed gearboxeses , it mainly include three parts : The first part , to make sure the basic parameter of the gearbox assurance ; The second part, The contact strength verify-check and the flection strength verify-check of each wheel gear of the gearbox, mainly verify whether each wheel gear satisfy various strength conditions with according to the giving parameter ; The third part , to progress verify-check intension of the axes Four-part cent, to calculate the life of the bearings.

本次设计是要设计一部较为完整的五档变速器,其中主要包括三部分:第一部分,变速器基本参数的确定;第二部分,变速器的各档齿轮的接触强度校核和弯曲强度校核,主要是根据所给的参数来验证各档齿轮是否满足各项强度条件;第三部分,进行轴的强度校核;第四部分,轴承的寿命计算。

A 300-Year Error-----Three-Hundred-Year Devil's DEN on NB of SNB, Two Decrypting Equation Books of 《 The Laws (ISBN1442131241)》 and 《 The Laws Plus (ISBN144213285X)》; A Three-Hundred-Year Error's Decryption, The Sword of the Third Signorino—Nostradamus' Sword of Great Seven Number that Makes the Global 6.5 Billions People Be Not Any More Buried Alive by the Earthquake in the World; Ali Baba and the Forty Thieves Open Simsim to the Sun and Moon Treasure House of the God to Get the Heaven's Nuclear Cimelia: Nuclear Les Trois Mousquetaires and Big Three's Triumvirate Carry out Three Nuclear Controls and Monitors to Make the Global 6.5 Billions People No Longer Lie Under Big Deathful Nuclear Radiation Here and There

全球拉响核警报:核泄露、核块熔化,全球15%以上核弹参与,同时大面积污染土壤和水资源,全球80%以上的人遭受严重核放射性照射辐射一个300年的错误;两本解密方程书《 The Laws (ISBN1442131241)》和《 The Laws Plus (ISBN144213285X)》;三百年错误的纠正令全世界65亿人从此不用再被地震无情活埋和被海啸无望吞噬;核三剑客令全世界65亿人从此不用再遭受致命核辐射

Studies on the Photosynthesis of Several Trisomics in Chinese Cabbage Brassica campestris ssp. pekinensis (Rupr. Olsson;3. The karyotype of triplo 6 of indica IR36 trisomic is analysized, and the additional chromosome is inentified.

本研究以籼稻IR36第六号三体(triplo6)为材料,进行了水稻体细胞核型分析,同时鉴定验证了三体材料,并为水稻标准核型图的建立提供了一些依据。

Results The frequencies of micronucleated binucleated cell in 30 nmol/L FA were significantly higher than those in 60, 120, 240, 2 260 nmol/L FA (P.001~0.05), but no significant differences were observed either between those in 60 and 120 nmol/L FA, or between those in 120, 240 and 2 260 nmol/L FA within either groups when the genotype was the same.

结果 MTHFR C677T三种基因型的乳腺癌个体与对照组淋巴细胞在叶酸浓度为30 nmol/L时双核细胞微核率均显著高于60、120、240和2 260 nmol/L测试组(P.001~0.05),60 和120 nmol/L 两个测试组之间以及120、240和2 260 nmol/L三个测试组之间都未发现显著性差异。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速,应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等,其中自杀基因被认为是最有前景的基因治疗方法,它又称病毒介导的酶/药物前体疗法,是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中,该基因表达的产物可将无毒的药物前体转化为毒性药物,从而选择性杀伤该肿瘤细胞,常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因,前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物,然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷,作为DNA合成链的终止剂和DNA合成酶的抑制剂,干扰细胞DNA的合成;后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶(5-FC)脱氨成为5-氟尿嘧啶(5-FU),然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸(5-FUTP)和5-氟-2′脱氧尿嘧啶-5′磷酸(5-FdUTP),5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成,5-FdUTP则作用于胸苷合成酶,导致TMP衰竭而阻止DNA的合成,最终诱导肿瘤细胞凋亡。

The cytoarchitectonic organization ofprojections to the insular cortex and the amygdala from the parvicellular ventroposterior nucleus of the thalamus andtheparabrachial nucleus in the rat was investigated by means of horseradish peroxidase -tracing technigue; The relationship of origins of afferents to the insular cortex and the amygdala from the PBN was studied by using the retrograde transport of two fluorescent tracers; Thesynaptic connections of axonal terminals with the neuronsof the PBN were observed by means of electron microscopy.

GI主要位于岛皮质的尾侧部,DI和AI主要位于首侧部;VPpc是位于丘脑腹后核和内侧丘系之间的带状区,所含细胞较小(平均14u),其内侧部称为腹后内侧核小细胞部,其外侧部称为腹后外侧核小细胞部;PBN位于小脑上脚周围,由三部分组成:外侧亚核、内侧亚核和Kollikor-Fuse核,其中,PBl被分为7个区、PBm被分为3-4个区;杏仁核主要由三个细胞群组成:皮质内侧核群、基底外侧核群和中央核,中央核又有内侧部、外侧部和外囊部之分。

A series of copper halides in one, two, or three dimensions have been successfully synthesized such as rhomboid dimers of stoichiometry [Cu2X2L2]n, the tetranuclear species on cubane or stepped cubane tetramers of stoichiometry [Cu4X4L4]n and hexagonal[Cu6X6] grid chains.2 The main strategy in crystal engineering is a secondary building block approach.3 For a given building block, there are two routes to construct frameworks.

在一维、二维或三维的一系列卤化铜已经成功地得到了合成,比如化学计量法[Cu2X2L2]n的长菱形二聚物、化学计量法[Cu4X4L4]n和六边形[Cu6X6]网格链的在立方烷上的四核类或阶梯式立方烷四聚物。[2] 在晶体工程上的主要策略是一种次级构件途径。[3] 对于一给定的构件来说,有两条构件骨架的路线。

The tripolar structure SST anomalies over the North Atlantic, which also appears at the interannual scale with a spectral peak at 3—4 years, are mainly resulted from the barotropic driving of the NAO like atmospheric forcing, and thermal process plays a dominantrole in this process. When the NAO is strong, the westerly weakens over the midlat itudes; both the sensible and the latent heat flux release from the ocean tend to decrease, which warms the ocean and leads to positive SST anomalies. Over the sub polar region including the Labrador Sea, a stronger NAO is associated with a deeper Icelandic Low; the high latitudes originated colder air then blows over the ocean surface, the air-sea temperature difference become larger, and the se n sible heat flux loss from the ocean increases, which subsequently leads to colder SST anomalies.

分析表明,模式中三核型SST异常的产生,主要来自大气的强迫,NAO增强,中纬度大洋上的西风减弱,海洋感热和潜热通量损失减少,中纬度大洋得到的净热通量增加,导致SST出现正距平;在包括Labrador 海在内的副极地大洋,NAO增强、冰岛低压加深,气旋性环流增强,来自高纬度的冷空气吹过洋面,海气温差加大,大洋的感热通量损失增加,SST降低。

After the click reaction of the SCL micelles and azide-terminus PNIPAM homopolymer, the novel PNIPAM-functionalized SCL micelles with pH-responsive cores and outer thermosensitive coronas were prepared, which was investigated act as excellent candidate of nanosized drug delivery vehicles.

另外,还可以使用溴丙炔对ATRP聚合出的PMEO_2MA-b-PDMA-b-PDEA三嵌段的中间PDMA嵌段进行部分季胺化,这样可以利用两端叠氮化的四甘醇来交联由PMEO_2MA-b-PDMA-b-PDEA在不同条件下形成的两种分别以PMEO_2MA或PDEA为核的胶束,从而实现了从同一个聚合物直接在水溶液中得到两种内核不同敏感的壳交联胶束。

The genes of hammerhead ribozymes targeting against two and three sites on negative strand of potato spindle tuber viroid were designed, synthesized and cloned according to the action manner of hammerhead ribozyme.

根据锤头型核酶的作用模式,设计、合成并克隆了特异切割马铃薯纺锤形块茎类病毒负链RNA不同区域位点的双价和三价锤头型核酶基因。通过体外转录,将PSTVd负链RNA分别与双价和三价核酶混合,37℃温育 2h。

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

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