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We have studied the transition metal complexes catalyzed sequential cross coupling reactions of these new difunctional group reagents with electrophiles and nucleophiles, respectively; developed some convenient and practical new methods for the stereoselective synthesis of disubstituted alkenes, trisubstituted alkenes, conjugated dienes containing heteroatom, conjugated enyne containing heteroatom etc., enriching methodologies for organic synthesis.

继而研究了这些新型双官能试剂在过渡金属配合物催化下分别与亲电试剂、亲核试剂的顺序交叉偶联反应,为双取代烯烃、三取代烯烃、杂原子取代的共轭二烯烃、杂原子取代的共轭烯炔烃等的立体选择合成提供了方便实用的新方法,丰富了烯烃立体选择合成的方法学。

Chapter III describes the history and experiences of plebiscite in Taiwan.

第三章描述公民投票主张在台湾的历史与实践经验:这部分将溯及到1947年廖文毅对台湾地位问题意见开始论述,次而对1970至1980年代公民投票与台湾地位的问题作探讨,依其历史演进至1990年代台湾公民投票案例:后劲反五轻、贡寮反核四以及台中反拜耳等等之政策议题,藉此分析我国公民投票制度的起源,论述台湾公民投票的历史轨迹和演进阶段,从制度变迁的轨迹中,分析我国公民投票法制化的政治意涵。

The primary survival structure of S. sclerotiorum is the sclerotium. A sclerotium is a hard resting structure consisting of a light colored interior portion called a medulla and an exterior black protective covering called the rind. The rind contains melanin pigments which are highly resistant to degradation, while the medulla consists of fungal cells rich in β-glucans and proteins.

三叶草核盘菌的活体结构主要是菌核,菌核是一种坚硬的静态结构,由颜色艳丽的髓质内核和黑色的蛋白质外壳组成,外壳含有对降解具有高度抗性的黑色素,而髓质则由富含β-葡聚糖和蛋白质的真菌细胞组成。

In these reactions the alkyl and alkyloxy groups in the 4-positions are displaced by the arylamino-group. Since the enzyme tyrosinase exits in melanoma cells and it is uniquely associated with melanocytes, which suggested a highly focused drug delivery system.

基于该反应机理,设计了酪氨酸酶的三个前药模型化合物并进行了体外模型实验,即以酪氨酸酶的底物苯酚和邻氨基苯酚作为药物布洛芬和5—氟脲嘧啶的载体,经酪氨酸酶和亲核试剂的作用,实现药物的释放。

In all those complexes, no matter which conformation IDA assumes (mer- or fac-style), the two 0 atoms of 1N2O are both from carboxylic hydroxyl. However, by comparing the bond length, we can find that O(4) and O(2) atom is from different group in this complex, 0(4) atom from carboxylic hydroxyl, whereas, 0(2) from carboxylic carboxide.

值得注意的是:在这个双核配合物中,我们首次发现一种新颖的配位方式:IDA上与金属离子配位的三齿螯合原子是亚氨N原子、一个羧基上的羟基O原子和另外一个羧基上的羰基O原子。

Based on calculating the first-order corrections to the energy from relativistic and mass-polarization effects, we estimate the higher-order relativistic contribution and QED correction to the energy under a hydrogenic approximation. The transition energies, wavelengths and oscillator strengths for the 1s23s-1s2np transitions of this ion are calculated.

在计算相对论效应和质量极化效应对体系能量的一级修正的基础上,通过引入价电子的有效核电荷,在类氢近似下,估算了对能量的高阶相对论修正和QED修正,计算了该离子1s23s-1s2np的跃迁能,波长和在三种规范下的振子强度。

E.coli RNA polymerase can transcribe all the genes of E.coli, but the three eukaryotic RNA polymerases transcribe only specific, nonoverlapping subsets of eukaryotic genes.

eukaryotic genes 大肠杆菌的RNA聚合酶能够转录所有的基因,但真核生物的三种RNA聚合酶各自只能转录特定的、不相重叠的一组基因。

This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution.

这次全面分析包含了三种动物的基因组序列和蛋白产物以及它们与人类疾病相关性分析,重复序列,哺乳动物同源染色体区域和重排断点的比较基因组研究,祖先核型的重建,产生现有种群的事件,变异率以及种系特异和不依赖种系的事件如基因家族扩展,同源关系以及蛋白进化。人类19号染色体序列被破译了。

This first comprehensive analysis includes genes and proteins and their relation to human disease, repeated sequences, comparative genome-wide studies of mammalian orthologous chromosomal regions and rearrangement breakpoints, reconstruction of ancestral karyotypes and the events leading to existing species, rates of variation, and lineage-specific and lineage-independent evolutionary events such as expansion of gene families, orthology relations and protein evolution.

这次全面分析包含了三种动物的基因组序列和蛋白产物以及它们与人类疾病相关性分析,重复序列,哺乳动物同源染色体区域和重排断点的比较基因组研究,祖先核型的重建,产生现有种群的事件,变异率以及种系特异和不依赖种系的事件如基因家族扩展,同源关系以及蛋白进化。生物谷评论:人类19号染色体序列被破译了。

Comparison from the Germany isolate, phocine distemper virus type Ⅱ(PDV-2) and vaccine strain, the major difference is the long signal peptide domain while the mature protein exhibit high identity, and all of the 13 serine residues, four potential asparagine glycosylation sites and two hydrophobic regions supposed to affect the fusion function are completely identical. These data supports the view that F protein is more conservative than H protein in CDV.

三、犬瘟热病毒中国分离株囊膜糖蛋白基因免疫小鼠诱发的抗体应答经一系列步骤将CDV-YZ0101株的两囊膜糖蛋白基因定向导入真核表达载体pcDNA3.1中,DNA测序和酶切分析筛选阳性重组质粒克隆pcDNA-H和pcDNA-F,以重组质粒DNA和脂质体共转染COS-7细胞,用间接免疫荧光试验证实转染的COS-7细胞的胞浆中分别表达了CDV的H和F蛋白。

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场,你等着挨绳子吧!

Several theories about reigniting and extinguishing of the arc have been refered.

本文综合考虑了几种电弧重燃和熄灭理论。