三核的

Three different numerical iterative algorithms are developed and the accuracy and stabilities of them are compared. Tension and compression instabilities are studied and effects of Conservative Smoothing Approach and artificial viscosity on stabilities are discussed. Based on Taylor series expansion, Modified SPH method is proposed. The discrete forms of the function and its first derivative estimations of the kernel function are deduced in both one and two dimensional space.

讨论了三种不同的数值迭代算法对计算精度和稳定性的影响；分析了不稳定性产生的根源，包括拉伸不稳定和压缩不稳定，探讨了保守光滑算法和人为粘性对稳定性的影响；在Taylor展开的基础上提出了一种修正的SPH方法，并推导一维和二维情形下函数的核估计和函数的一阶导数核估计的离散形式，结果表明，二维情形下MSPH方法可以很好的改善边界粒子的计算精度。

In complex 1,Cucan be described as a four-coordinated square planar geometry.Compound 8 is the sodium salt of plumbagin and exists as ionic compound.Compounds 9-16 are the rare earth complexes of plumbagin with La,Y,Dy,Sm,Gd,Nd,Erand Eu.Compound 17 is binuclear Y complex.18 is mononuclear Ycomplex with plumbagin and another ligand from Plumbago Zeylanica.Compounds 19-21 are the ternary complexes with plumbagin and 2,2\'-bpy and phen as assistant ligand.In 19, the geometry of Cucan be described as five-coordinated distorted square pyramid that exists in a dimer through the weak bonding,and 1-D chain structure is formed by intermolecular hydrogen bonds.

化合物1的单晶结构分析表明1具有四配位平面四边形结构，化合物8是白花丹素的Na盐，以离子化合物形式存在；化合物9～16为白花丹素的La，Y，Dy，Sm，Gd，Nd，Er，Eu的稀土金属配合物；化合物17是白花丹素的双核钇结构；化合物18为白花丹素的单核钇结构，该配合物除了含白花丹素外，还有来自白花丹植物中的另一个单体化合物也参与配位；化合物19～21是以2，2\'-联吡啶和邻菲咯啉等含N配体为辅助配体，具有白花丹素—含N配体—金属离子的三元配合物，化合物19是白花丹素和2，2\'-联吡啶与Cu的配合物，具有五配位的四方锥构型，通过Cu…O弱的成键作用形成二聚体，再通过分子间的氢键作用进一步形成一维链状结构，化合物20和化合物21是白花丹素分别与2，2\'-联吡啶和邻菲咯啉的Zn配合物，都具有六配位八面体构型的双核锌配合物，呈一维链状结构，化合物20中链与链之间的大量氢键将一维链扩展成二维层，分子间的π-π堆积作用进一步形成三维结构。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果：1、哇巴因作用于晶状体钠泵后，光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙，电镜下全层细胞空泡化、线粒体肿胀出现髓样结构，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后，光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离，电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后，光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整，电镜下细胞器丰富、细胞功能旺盛，RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后，光镜下晶状体质膜完整、细胞排列紧密规整，电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝，RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后，光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化，电镜下囊侧膜内有高电子密度带、细胞核仁丰富，RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后，光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏，电镜下质膜变性、线粒体肿胀，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

The metal ions of the dinuclear copper complex of [Cu_2_2Cl_4] are linked by two N~1,N~2 1,2,4-triazole bridges,and the central Cu ions have distorted trigonal bipyramid geometries. The central Cu ion of [CuL22]·H2O has a centrosymmetric and distorted tetragonal-octahedral geometry. The metal ions of the dinuclear manganese complex of [Mn_2L_2_2Cl_2(H_2O)_2] are bridged by two chlorine atoms, and the central Mn ions have distorted tetragonal-octahedral geometries. Part III.

配合物[Cu_2_2Cl_4]是通过配体L的1，2，4-三唑环上两个氮原子(N~1，N~2)桥联形成的双桥双核配合物，每个中心铜离子都具有畸变的三角双锥构型；配合物[CuL22]·H_2O的中心铜离子具有中心对称的畸变八面体构型；配合物[Mn2L2_2Cl_2(H_2O)2]是通过两个氯原子桥联形成的双桥双核配合物，每个中心锰离子都具有畸变的八面体构型。

The whole brain of the subject was axially and coronally scanned in the normal stereotactic space with a slice 1mm thick by MR system. The caudate nucleus were identified, segmented, extracted, saved and three-dimensionally reconstructed on MRI by software system developed by Research Center of Biology, Harbin University of Technology.

在以AC-PC线为基准线的标准脑立体定向空间对志愿者做1mm层厚，间距0mm的MR轴位和冠状的脑扫描，利用哈尔滨工业大学生物研究中心研究开发的软件系统对经MRI扫描后转存的尾状核图像进行三维重建，软件提取分割的尾状核轮廓后执行重建命令。

A new theoretical model, the 2CLJDQP potential function, was developed for linear molecules, which takes into account dipole, quadrupole and induction effects as well as the rotation of the dipole out of the molecular axis. The energy parameters were optimized for various types of fluids. With the modified mixing rules, the potential parameters obtained from homonuclear molecules can be used to calculate the second virial coefficients of heteronuclear molecules. The model was also successfully extended to triatomic molecules. Analysis of the contributions to the second virial coefficients of long-range interactions shows that the molecular interactions introduced in the present model, such as, the induction effects, cannot be neglected.

建立了全新的线型分子2CLJDQP势能模型，考虑了偶极作用、四极作用及诱导作用的影响，还考虑了极轴与分子轴不平行的情况；回归了多种线型分子的势能参数；通过改进混合规则，可应用同核线型分子的势能参数直接计算异核线型分子的第二维里系数；扩展该模型可用于线型三原子分子计算；讨论了各长程引力项对第二维里系数的贡献，结果表明本模型引入诱导作用等是十分必要的。

Oncogenes, existing widely in eukaryotic cells, take part in the processes of cell prolification and differentiation. c-fos and c-jun are two important oncogenes in CNS, and can be rapidly expressed in response to stimulations and injuries of nervous system, Oncogene proteins play very important rules as "nuclear third messengers"during signal transduction in CNS.

癌基因广泛存在于真核细胞内，参与细胞的增殖分化等活动。c-fos和c-jun是神经系统内两种十分重要的癌基因，受到外来刺激或神经系统损伤时，可以有快速的表达，其编码的蛋白产物作为一种&核内第三信使&参与调节细胞的信号转导过程。

Organic matrixs coming from cells play role in nucleation, growth, morphology, polymorphology of inorganic materials. This control of organic matrixs are mainly behaved by the interfaction between organic matrix and inorganic materials .The processing of organic matrix controlling inorganic material is called as molecular recognition. The mechanism of organic-inorganic molecular recognition contains three facts such as electrostatic attraction, lattice geometry matching and stereochemical complimentary.

细胞分泌的有机基质在无机矿物的成核，生长，形貌，多型和结晶学定向等过程中起到了调控作用，基质对矿化的这种调控作用具体表现在有机或生物大分子和无机离子在界面上的相互作用，有机质对无机晶体的成核，生长，晶形及结晶学定向等的控制过程称为分子识别，有机-无机界面分子识别机制主要包括静电作用，晶格几何匹配和立体化学互补三个方面。

Through cyclic hydrogen bonding with motif formed by coordinated water molecules and coordinated hydroxyl groups of dhbd from adjacent tetranuclear units, these adjacent neighbors are connected to afford a 1D supramolecular chain along axis a, which is further extended via aromatic intercalations and other crystallization water molecules into a 3D structure with channels.

毗邻的四核单元通过配位H2O分子和配位羟基O原子形成的 R 22(8)型环形氢键桥的连接，沿a轴方向构建了四核单元交替相连的一维超分子链；链间籍苯环的π-π堆积作用和晶格水分子氢键链的连接进一步扩展为具有隧道的三维结构。

The relationship of the amounts of emulsifier, organosilicon monomer (D4) and initiator with the ratio of fluorescence intensity between first vibronic peak of pyrene (λ= 373 nm) and third vibronic peak of pyrene (λ=384nm)Ⅰ1/Ⅰ3 were discussed during the emulsion polymerization process, in which pyrene was used as fluorescence probe. The polymerization behavior of the organosilicon-acrylate latex with core-shell structure was investigated in line with the relationship of monomer conversion and development of morphology in latex particles with the value of Ⅰ1/Ⅰ3 for probe pyrene during the polymerization process.

以芘为荧光探针，探讨了有机硅-丙烯酸酯核壳乳液聚合过程中，芘的第一振动峰(373nm处)与第三振动峰(384nm处)荧光强度的比值Ⅰ1/Ⅰ3与乳化剂、有机硅单体（D4）和引发剂用量之间的关系，并结合聚合过程中探针芘的Ⅰ1/Ⅰ3 峰值与单体转化率及乳胶粒形态演变之间的关系，研究了核壳结构有机硅-丙烯酸酯乳液的聚合行为。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！