三态性

Kanzawa pointed, the abdominal vertebra BMD of PTH gene individuals in BB genetype is obviously higher than those of Bb and bb genetype,so he considered that the BstBI polymorphism of PTH gene has dependability with BMD while the DraⅡpolymorphism of PTH gene has no dependablity with BMD.3 The polymorphism of estrogen receptor gene and postmenopausal osteoporosisPMOP is a metabolic bone disease existing in post-menopause femmes, as a result of these femmes\' hypofunction of ovary,ESG level drawdown and the disequilibrium of bone couple procedure,the bone resorption of osteoclast exceeds the bone formation of osteoblastic,osteopenia and bone fragility accrescence have developed,then induces fracture and so on.

Kanzawa等研究发现，BB型PTH基因人的腰椎BMD较Bb、bb型显著为高，认为PTH基因BstBⅠ多态性与BMD有相关性；但PTH基因DraⅡ多态性则与BMD无相关性。三雌激素受体基因多态性与绝经后骨质疏松绝经后骨质疏松是指绝经后妇女由于体内卵巢功能低下，雌激素水平低落，骨偶联过程失衡，破骨细胞的骨吸收大于成骨细胞的骨形成作用所导致的骨量减少，骨脆性增加，进而易于发生骨折的代谢性骨疾病。

The analysis of genetic diversity between different chromosomes showed that the polymorphic loci distribution of Chr.6,Chr.9 and Chr.11 was evener and the polymorphism information content was also more than others chromosomes.

不同染色体间的遗传多样性分析结果表明，Chr.6、Chr.9、Chr.11三条染色体的多态性位点分布较均匀且多态性信息含量也较多，整体遗传多样性丰富程度高于其他染色体。

Meanwhile, Tibetan sheep (breeded in Sanjiaocheng of Qinghai, Huangcheng and Gannan of Gansu ), Mincounty Blank Fur sheep and Texel and Poll Dorset were controlled. The results indicated that polymorphism was tested at the loci of Hb, Tf and Es, that erythrocyte protein 1 and 2 were monomorphism. There were a couple of allele and three genotypes at the loci of Hb and Es. There were 10 genotypes at the locus of Tf, which was determined by 5 alleles.

结果表明，青海细毛羊和甘肃高山细毛羊的血红蛋白、转铁蛋白和酯酶基因座上存在丰富的多态性，其中Hb和Es位点受一对等位基因控制，共构成3种基因型；Tf位点受5个等位基因控制，共构成10种基因型；而红细胞蛋白质-1（EP-1）和红细胞蛋白质-2（EP-2）基因座均呈显单态；青海细毛羊的AMY基因座具有AMY1、AMY2、AMY3三种同工酶，其中AMY2呈多态，有AMY2A和AMY2O两种表现型，而甘肃高山细毛羊的AMY呈显单态。

18 Patients with radioresistant NPC and 30 patients with radiosensitive NPC are included in the case-control study. Genomic DNA was extracted from peripheral blood lymphocytes by proteinase K digestion and phenol/chloroform extraction.

本研究旨在通过调查MDR1基因的单核苷酸多态性在鼻咽癌放射敏感和放射抵抗患者中的分布以及上述多态性对MDR1 mRNA在分具不同放射敏感性的三株细胞系内的差异表达的影响，探讨MDR1基因多态性与鼻咽癌放射敏感性的相关性。

The apoB gene polymorphism on Xba I site of 53 6 unrelated Chinese Han people,aged 25～64 years,was analyzed using PCR and Re striction Fragment Length Polymorphismmethod;serum apoA I,apoB,total chole s terol,triglyceride,HDL cholesterolwere measured,and LDL choleste roland non-HDL cholesterolwere calculated.

采用聚 合酶链反应结合限制性片段长度多态性分析的方法，分析536名25～64岁的无血缘关系的汉族人的apoB基因Xba I位点多态性，并测定其血清apoA I、apoB、总胆固醇、甘油三酯、高密度脂蛋白胆固醇，并计算低密度脂蛋白胆固醇LDL-C）及非高密度脂蛋白胆固醇。

Methods:The polymerasechain reactionand restriction fragment length polymorphismtechniques were used to detect both Hind III and Pvu IIpolymorphisms in 92 children with simple obesity and 80 healthycontrols.The levels of the plasma lipid,plasma lipoproteins,bodymass index,blood pressure,waistline,chest circumference,gluteal circumference,skinfolds thickness at three measuring points(biceps,subscapular and abdominal wall)were also measured.

应用聚合酶链反应和限制性内切酶片断长度多态性技术，检测了92例单纯肥胖症儿童和80例正常健康儿童的LPL-Hind III与LPL-Pvu II基因多态性，并测定血脂、BMI、血压、腰围、胸围、臀围、以及肱二头肌、肩胛下、腹壁等三个部位的皮褶厚度。

Fingerprints of broiler chickens divergently selected for very low den sity lipoprotein in fat line and lean line of the third generation were studied using inter simple sequence repeated technique. Geneti c polymorphism and genetic similarity coefficient between two groups were analyze d. Ten primers were screened from 60 SSR primers and 62 sites were deprived. Of which 39 bands were polymorphic sites and the frequency was 63 percent.

通过对初步进行血浆极低密度脂蛋白双向选择的三世代高、低脂群肉鸡进行ISSR指纹分析，评定其遗传多态性及两群体间的遗传相似系数。60个引物筛选出10个引物用于检测分析；共扩增出62条谱带，其中39个是多态性片段，多态率为63%。

The amplified fragment length polymorphism technique was used to assess the genomic DNA polymorphism of four species Emberiza (cioides, leucocephala, tristrami and spodocephala). Eleven pairs out of thirty-nine AFLP primer pairs produced reproducible polymorphic DNA amplification patterns.

利用扩增片断长度多态性技术分析了鹀属4种鹀（三道眉草鹀Emberiza cioides，白头鹀Emberiza leucocephala，白眉鹀Emberiza tristrami，灰头鹀Emberiza spodocephala）基因组DNA的多态性。

Based on the perturbation theory,the influences of the Fermi resonance interaction between the two and three vibronic levels on the level energy,wavefunction,and the spectral line intensity are investigated in detail respectively.

本文考虑了分子振动非谐性所引起的振动能级之间的费米共振相互作用，利用定态微扰论，从理论上系统地分析了两态和三态之间的费米共振相互作用对能级能量、态函数和谱线强度的影响，在三阶非谐性近似下，得到了计及费米共振相互作用在内的能级能量、态函数和谱线强度的数学解析表达式。

In this study, We typed the the gene of β〓-AR from genomic DNA of asthmatic patients and made the further analysis: The distributing condition of genetic polymorphisms at positions 16 and 27 in β〓 AR coding region and at position 19 in 5'Leader Cistron (5'LC) among southwest Chinese asthmatic population; The relationship between the each polymorphisms at the above three positions and the asthmatic phenotypes (FEV〓 or nocturnal asthma); The effect of each polymorphisms at the above three positions on bronchodilator responsiveness induced by β〓- agonists(initial bronchodilator response, pharmaco-dynamic); The relationship between the haplotypes of polymorphisms in the 5'LC or in positions 16, 27 of β〓AR coding block and asthmatic phenotypes or bronchodilator responsiveness induced by β〓-agonists.

实验通过对哮喘人群的β〓-AR基因进行分型，探讨：β〓-AR编码区16、27位点及5'前导肽(5'LeaderCistron，5'LC)19位点遗传多态性在中国西南地区哮喘人群中的分布情况；三个位点多态性与哮喘临床表现型的关系；三个位点多态性对β〓受体激动剂反应性(支气管舒张反应，舒张反应动力学)的影响；16、27位点及5'前导肽19位点遗传多态性单倍型与哮喘临床表现型及β〓受体激动剂反应性的关系。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。