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三叉神经

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The immunohistochemical staining, cell-size frequency analysis and the survey of average optical density value were used to observe the changes of TRPV1 expression in the neurons of the trigeminal ganglion, peripheral nerve fibers in the vibrissal pad, and central projection processes in the trigeminal sensory nuclei caudalis on day 3, 5, 7, 14, and 21 after TO injection.

应用免疫组织化学染色,细胞大小频率分析和平均光密度值分析来研究面部炎症痛后第3、5、7、14、21天支配大鼠面部表皮区三叉神经节(trigeminal ganglion,TG)初级感觉神经元、触须部皮肤末梢神经纤维和投射至三叉神经感觉尾侧亚核(trigeminal sensory nuclei caudalis, Vc)中枢突TRPV1表达的改变。

This study showed that the occurrence rate of imaging diagnosis of cranial nerves involvement decreased in sequence:mangibular nerve 18 percent, cavernous sinus 17 percent, hypoglossal nerve13 percent, trigeminal ganglion 10 percent ,(glossopharyngeal nerve, vagus nerve, accessory nerve) 6 percent.

本研究显示受累颅神经的影像诊断发生率依次递减为三叉神经第3支受累18%、海绵窦17%、舌下神经13%、三叉神经半月结10%、舌咽/迷走/副神经6%。

The gross anatomy of trigeminal nerve rat was similar to human, but the rat ophthalmic nerve combined with the maxillary nerve formed one long nerve trunk that reach to the orbital apex. The trigeminal nerve of rat could be showed clearly on MR images.

大鼠的三叉神经解剖结构与人类相似,主要不同是大鼠三叉神经眼支与上颌神经合为一个神经干,达眶尖处分开;大鼠的三叉神经较粗大,在1.5T MR成像系统可以被清楚地显示。

FasL immunopositive neurons were observed in cerebral cortex, especially in pyramidal neurons of lamina Ⅱ and Ⅴ, cerebellar nuclei, diencephalon, and brain stem nuclei involving pontine nucleus, vestibular nucleus, cochlear nucleus, spinal nucleus of trigeminal nerve, hypoglossal nucleus, nucleus ambiguous and reticular formation.

间脑中有FasL阳性神经元分布。在脑干,Fas主要分布于前庭神经核、迷走神经背核和三叉神经脊束核的神经元;FasL广泛分布在脑桥核、前庭神经核、三叉神经脊束核、舌下神经核、蜗神经核、网状结构和疑核。

The results revealed that the volume, density and gray cell coefficientof nucleus sensorius n trigemini are the largest (10.36mm~3, 32×10~3/mm~3,29.08), but the mean of the size of its neuron perikaryon is the smal...

抽样测定了舌下神经核、展神经核、滑车与动眼神经核、面神经核、三叉神经运动核和三叉神经感觉核的神经核体积、神经细胞数和神经细胞大小,计算出各核的神经细胞密度、各类细胞的百分数和灰质细胞系数,并进行了讨论。

By ABC-immunohistochemical technique combined with LBAS- LUZEX-F computer automatic pictural analysis system, we detected the HSV-1 antigens in cornea of HSK rabbit dynamically.

通过对HSK兔三叉神经节病理形态学及定量免疫组织化学研究,首次定量分析了三叉神经节各分支区域神经原内HSV-1抗原分布情况,揭示SCRN抑制病毒抗原,保护神经细胞的作用。

Results: Lateral extradural approach could be used to expose the second and third branches of trigeminal nerve,trigeminal ganglion,posterior vertical segment of the intrapetrosal ICA,abducent nerve and horizontal segment of the intrapetrosal ICA;lateral intradural approach could be used to expose the lateral,anteroinferior and posterosuperior venous spaces,almost all the cranial nerves within the cavernous sinus and horizontal segments of the intracavernous ICA;superior approach could be used to expose the medial,lateral and posterosuperior venous spaces,medial side of the anterior genu,anterior vertical and clinoidal segments of the intracavernous ICA and the lateral side of the hypophysis.

结果:外侧硬膜外入路可用于显露三叉神经第2、3支,三叉神经节,海绵窦内颈内动脉后垂直段,外展神经及岩骨颈内动脉水平段;侧方硬膜下入路可用于显露海绵窦外侧及前下,后上静脉间隙,以及所有走行在海绵窦内的颅神经和海绵窦内颈内动脉水平段;上方入路可用于显露海绵窦内侧、外侧及后上间隙,海绵窦内ICA水平段、前膝、前垂直段及床突段的内侧面,以及垂体的外侧面。

Objective To study conductive features of trigeminal diseaseful evoked potential, in order to evaluate function of nervous system of original trigeminal neuralgia and numbness of trigeminal branch, bring out meaning that we measure evoked potential of trigeminal disease, therefore providing the theoretical foundation for treating the trigeminal disease in clinical medicine.

目的:寻找三叉神经疾患诱发电位的传导规律,评价原发性三叉神经痛和三叉神经末梢支受损致麻木的神经系统的功能状态,探讨三叉神经疾患体感诱发电位检测的意义,从而为临床诊治三叉神经疾患提供理论依据。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

Fulwiler CE, Saper CP. Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brian Res 1984;319:229-259.[2]Herbert H, Moga MM, Saper CB. Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J Comp Neurol 1990;293:540-580.[3]Slugg RM, Light R.

三叉神经脊束间质核(interstitial nucleus of the spinal trigeminal tract, INV)为位于延髓闩平面附近三叉神经脊束内及其周围的一些核团,由中、小型梭形、圆形或卵圆形细胞组成,经三叉神经的分支和迷走、舌咽神经接受外周内脏和躯体感觉信息[6,7]。

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