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Using 1,4-dibromobenzene,1,3,5-tribromobenzene and 2-methyl-3-butyn-2-ol as starting materials and PdCl2,triphenylphosphine,CuI and KOH as catalysts,1-bromo-4-ethynylbenzene,1,4-diethynylbenzene and 1,3,5-triethynylbenzene were synthesized by Sonogashina coupling reaction and elimination reaction.

以对二溴苯、1,3,5-三溴苯和2-甲基-3-丁炔-2-醇为原料,在PdC l2、PPh3和CuI的催化作用下进行Sonogash ina偶联反应,偶联产物在KOH作用下发生消去反应,分别得到对溴苯乙炔、对二乙炔基苯、1,3,5-三乙炔基苯。

Bezaldehyde was used as protective agent in first method.S-Epichloeohydrin was aminated and acidulated to give(2S)-1-Amino-3-chloro-propanol Salts.The acetylation of (2S)-1-Amino-3-chloro-propanol by acetic anhydride produced the intermediate-N-[2--3-chloropropyl]acetamide.And then at 20℃,in the presence of lithium tert-butoxide,benzyl 3-fluoro-4-morpholinophenyl carbamate react with-N-[2--3-chloropropyl]acetamide to give linezolid in total yield of 43.6%.

路线一采用苯甲醛作保护剂,使S-环氧氯丙烷氨解、酸化生成S-1-氨基-3-氯-2-丙醇盐酸盐,然后经乙酰化反应后,生成中间体-N-[2-乙酰氧基-3-氯丙基]乙酰胺,再用N-(3-氟-4-吗啉苯基)氨基甲酸苄酯和中间体在催化剂叔丁醇锂存在下25℃反应生成利奈唑酮,总产率达到43.6%。

This is a special reaction of arginine's carbamidine, which is useful in quantitating and determining the natures of protein and the amino acid.

这是由于蛋白质分子中精氨酸胍基的特征反应。许多胍的衍生物如胍乙酸、胍基丁胺等也发生此反应。

The results showed that Kaidimycin was chemically neutral, macrocylic polylactones, stable and liable to dissolve into water and pyridine, slight to dissolve into methanol, ethanol and N-butanol, difficult to dissolve into ethyl acetate, acetone, benzene and chloroform. Chemical reaction of functional group of Kaidimycin showed that it had glycoside, amino acid and aldehyde, no reducing sugar, polypeptide and phenol.

凯地菌素属中等极性的、中性抗生素,极性纸层析结果与多烯类抗生素的纸层析结果相似:易溶于水、吡啶,微溶于甲醇、乙醇、正丁醇,不溶于乙酸乙酯、丙酮、苯、三氯化碳;对高温、光照和紫外处理有很好的稳定性;官能团反应试验结果发现,凯地菌素可能含有糖苷键、氨基酸伯氨基和醛基,不含有还原糖、多肽和酚基,高锰酸钾、浓硫酸反应与多烯大环内酯类抗生素的特性相似;并且依据纯品,采用生物法和分光光度法对摇床发酵液进行了效价的测定。

Gull Island, off of Alaska"s Kenai Peninsula, is a refuge for hundreds of seagulls. One of Alaska"s most heavily trafficked areas, the Kenai Peninsula abounds with postcard views—snowcapped mountains, rivers that roil with spawning salmon, an abundant supply of moose, bears, eagles, and puffins, four active volcanoes, and a gigantic, otherworldly icescape, Harding Icefield.

海鸥岛,起飞阿拉斯加的& S基奈半岛,是一个避难所,数以百计的海鸥,其中阿拉斯加的& S最繁忙的地区,基奈半岛拥有丰富明信片的看法-冠雪做着山脉,河流,还有必要与产卵的鲑鱼,供应充足的驼鹿,熊,鹰,和海雀,四个活火山,以及一个庞大的, otherworldly icescape ,哈丁icefield 。

Augustine, for example, voices the prevailing Catholic sentiment when in reference to the Pelagian affair he declares, in a sermon delivered at Carthage after the receipt of Pope Innocent's letter, confirming the decrees of the Council of Carthage:"Rome's reply has come: the case is closed" Inde etiam rescripta venerunt: causa finita est.

131, cx;圣奥古斯丁,例如声音,当时的天主教情绪时,在参考该pelagian的内政,他宣称,在说教上发表的迦太基后,收到诺森的信,确认法令理事会迦太基:&罗马的答复来:此案是封闭的&(独立不错rescripta venerunt :原因finita估值血清131 ,国泰航空

The Machiavellians is intended to be "A defense of political truth against wishful thinking" which is achieved through a discussion of the political thinkers Dante, Machiavelli, Mosca, Sorel, Michels and Pareto.

马基雅维利信奉者试图通过对但丁、马基雅维利、莫斯卡、索列尔、米歇尔斯与帕累托的探讨,达成&捍卫政治真相,以对抗一厢情愿想法&的目的。

The inhibition effect of 2,2,6,6-tetramethyl-4-hydroxylpiperidine-oxyl and some phenols and quinones on the AIBN initiated radical polymerization of styrene was studied by using dilatomitry method.

用膨胀计法,研究了2,2,6,6-四甲基-4-羟基哌啶氧自由基及一些醌、酚类化合物对偶氮二异丁腈引发的苯乙烯自由基聚合的阻聚效应。结果表明,当 St在80℃聚合时,加入TMHPO·或TMHPO·-BQ,阻聚效果较为显著。

Ethambutol is a first-line drug used for antituberculosis therapy. It is often used in combination with isoniazid, rifampin, pyrazinamide, and streptomycin. The action of EMB in antituberculosis mechanism is the destruction of cell wall of tubercle bacilli via binding the target molecule -- arabinosyl transferases. These enzymes are involved in the polymerization of the cell wall arabinan. Inhibition of arabinan synthesis by EMB results in the accumulation of mycolic acids, leading to cell death.The EMB-resistance of MTB is involved with the mutation of emb operon or the over expression of emb operon.

乙胺丁醇是和异烟肼、利福平、链霉素、吡嗪酰胺联合治疗结核病的一线抗结核药物,EMB对结核分枝杆菌的作用机制与分枝杆菌胞壁结构破坏有关,主要作用于靶分子阿拉伯糖基转移酶,抑制了阿拉伯糖基聚合入阿拉伯半乳聚糖,从而影响细胞壁分枝菌酸-阿拉伯半乳聚糖-肽聚糖复合物的形成,导致菌细胞的死亡。

This thesis attempts to explore into the protagonist david levinsky's emotional innermost with the"i-thou" philosophy preached by martin buber, one of the most famous theological philosophers in contemporary world, and to illustrate the fact that levinsky's poverty in love after transforming from rags to riches is rooted in his deep-seated "i-it" outlook of the world.

本文通过结合当代宗教哲学家马丁·布伯的&相遇&哲学对该作品主人公戴维·莱文斯基的情感世界进行透析,指出莱文斯基之所以在成为百万富翁之后反而沦为情感上的乞丐主要是由于他的&我-它&人生哲学。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。