丁二酰

Photoreactions of 8 with 15-19, on the other hand, furnished the corresponding [2+2] cyclobutane products and the annulation products together.

二氯马来酰亚胺（8）与15—19的光化反应中则分别得到相应[2+2]的环丁烷产物和增环产物，在与19的反应中，还得到由环丁烷产物脱氯化氢后得到的环丁烯开环的二烯产物。

PP was taking as basic material,and blended with ethylene propylene rubberby means of melt blending to prepare easy openable infusion bottle-cover materials,in which a certain amount of LDPE and plasticizer was added to improve the compatibility and mechanical properties of the blend.

以聚丙烯为基材，与二元乙丙橡胶用熔融共混的方法，制备易开启式输液瓶外盖用料，并加入一定量的低密度聚乙烯和增塑剂以改善体系相容性和力学性能，讨论了增塑剂邻苯二甲酸二辛酯、乙酰柠檬酸三正丁酯及丙三醇对共混体系力学性能的影响。

METHODS: Fresh bovine tendo calcaneus collagen was dispersed in 0.5 mol/L acetic acid, co-precipitated with chitosan and lyophilized. Dry membranes were cross-linked in 0.05% glutaraldehyde for 24 hours. In vitro its degrading rate was measured by use of collagenase degrading test. The chitosan-collagen membrane was implanted to subcutaneous dorsal sites of SD rats. After implantation, histocompatibility, vascularity and degradation were observed in vivo.

以酸溶法制备胶原溶液，添加一定比例的脱乙酰化几丁质，冻干成膜，0 。0 5 %戊二醛溶液浸泡交联，行体外酶降解实验，检测其耐受酶降解能力；将制备的几丁质-胶原蛋白膜包埋于 36只 SD大鼠皮下，术后 3、5天，1、2、3、4、6、8和 12周取材，检测其组织相容性、血管化能力及材料在体内降解情况。

In this paper, the synthesis ways and applications of 4,5-dimethyl-l,3-dioxolen -2-one were introduced. An appropriate way synthesizing DMDO from acetoin via acylation, cyclization and dehydrochlorination was selected. The influences of various process conditions on the reaction were studied in detail, and the optimum process conditions were obtained by single factor experiments.

本文介绍了医药中间体4，5-二甲基-1，3-二氧杂环戊烯-2-酮的应用情况和合成路线，选择了适于工业化生产的工艺路线，即采用羟基丁酮为原料，经酰化、环合和脱氯化氢等步骤合成DMDO，并采用单因素试验法详细研究了各项工艺条件对反应结果的影响规律，确定了优化工艺条件。

A process for the carbonylation of allylic butenyl ether (for example, methyl crotyl ether, 3-methoxybutene-1 and mixtures thereof) or mixture of butadiene and alcohol and production of beta-gamma unsaturated carboxylic acid esters (for example, methyl-3-pentenoate) utilizing a rhodium-containing catalyst for example, dicarbonylacetylacetonate rhodium(I or the like promoted with an iodide-containing compound (for example, HI, AlI3, SnI4, TiI4, CrI3, and CoI2 or the like).

一种将烯丙型丁烯基醚(如甲基巴豆基醚、3－甲氧基丁烯－1及其混合物)或者丁二烯与醇的混合物羰基化的方法，以及由含碘化物化合物(如HI、AlI3、SnI4、TiI4、CrI3和CoI2或等效物)促进，用含铑催化剂如二羰基乙酰丙酮酸铑(I或其等效物制备β－γ不饱和羧酸酯(如甲基－3－戊烯酸酯)的方法。

Methods:The target compound was synthesized using 4-hydrazino-N-methyl-benzyl-sulphonamide hydrochloride and 4,4-dimethoxy-N,N-dimethyl butylamine as the starting materials,PPA and sodium dihydrogen phosphate instead as catalysts and isopropyl ether and acetone as solvents for recrylstallization,via 4-step reactions:condensation,rearrangement,cyclization and salt formtion.

以4-肼基-N-甲基-苄基磺酰胺盐酸盐与4，4-二甲氧基-N，N-二甲基-丁胺为起始原料，改用多聚磷酸和磷酸二氢钠作为催化剂，后处理采用异丙醚和丙酮作为重结晶溶剂，经缩合、重排、环合、成盐的4步反应合成琥珀酸舒马曲坦。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为：二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2，3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺，多烯他赛。

Four new salicylaldehyde derivatives with a glucose or mannose moiety were synthesized with 2-tert-butylphenol or 4-tert-butylphenol as the starting material, followed by the formylation, chloromethylation, nucleophilic substitution reaction with the desired carbohydrate. The salicylaldehyde derivatives condensed with ethylenediamine to give the Schiff bases, which coordinated with Mn to afford four novel sugar-based Salen Mn complexes.

首先，分别以2-叔丁基苯酚和4-叔丁基苯酚为起始原料，经过甲酰化反应、氯甲基化反应、和糖类衍生物的亲核取代反应制得了四种新型并入葡萄糖基或甘露糖基的水杨醛衍生物，将它们与乙二胺缩合生成希夫碱配体，得到的配体与过渡金属Mn~(3+)配位制备出四种新型含糖基的Salen Mn配合物。

The α-monobromination of 2-pentone,4-methyl acetophenone,4-methoxyacetophenone,6-methoxy-2-acetylnaphthane,2,2,5,5-tetramethyl-3-hexanone,cyclooctanone,cyclododecanone with respectively,were studied.

研究了离子液体三溴化1-丁基-3-甲基咪唑[Br3]对2-戊酮、4-甲基苯乙酮、4-甲氧基苯乙酮、6-甲氧基-2-乙酰基萘、2，2，5，5-4-甲基-3-己酮、环辛酮、环十二酮、丁醛等羰基化合物的α-溴化反应。

Propargyl alcohol was protected by dihydrophran with the catalysis of PPTS ,and then reacted with Ethyl Mag bromide to prepare its corresponding Grignard reagent.

炔丙醇在 PPTS 催化下由二氢吡喃保护，与溴乙烷格氏试剂反应生成相应的格氏试剂，然后与氯甲酸甲酯反应得到羟基丁炔酸甲酯四氢吡喃醚，在 PPTS 催化下脱保护后进行甲磺酰化，由溴化钠进行溴取代后合成了4-溴-2-丁炔酸甲酯，总收率达53%。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。