丁二胺

Main products: Ifosfamide,Ifosfamide acylate,2-Deoxy-D-Glucose, Vecuronium Bromide Oteracil Potassium,Gimeracil,Cinildipine,, Ceftiofur Hcl,Ceftiofur Sodium,Buflomedil Hcl

主要产品有：异环磷酰胺、异环磷酰胺酰化物、2-脱氧-D-葡萄糖、维库溴铵、盐酸头孢噻呋、头孢噻呋钠、氧嗪酸钾、吉莫斯特、西尼地平、盐酸马尼地平、培美曲塞、培美曲塞酸、培美曲塞二钠、尼索地平、消旋卡多曲、雷尼酸锶、盐酸丁咯地尔、1-(3-三氟甲基苯基)哌嗪盐酸盐、4-溴-2-甲基苯甲酸。

Main products: Ifosfamide,Ifosfamide acylate,2-Deoxy-D-Glucose,Vecuronium Bromide, Ceftiofur Hcl,Ceftiofur Sodium,Buflomedil Hcl,Oteracil Potassium,Gimeracil,Cinildipine,Manidipine dihydrochloride,Pemetrexed intermediate,Pemetrexed acid,Pemetrexed Disodium, Nisoldipine, Racecadotril, Strontium Ranelate, 1-(3-Trifluoromethylphenyl)piperazine hydrochloride, 4-Bromo-2-methylbenzoic acid.

主要产品有：异环磷酰胺、异环磷酰胺酰化物、2-脱氧-D-葡萄糖、维库溴铵、盐酸头孢噻呋、头孢噻呋钠、氧嗪酸钾、吉莫斯特、西尼地平、盐酸马尼地平、培美曲塞、培美曲塞酸、培美曲塞二钠、尼索地平、消旋卡多曲、雷尼酸锶、盐酸丁咯地尔、1-(3-三氟甲基苯基)哌嗪盐酸盐、4-溴-2-甲基苯甲酸。

Main products: Ifosfamide,Ifosfamide acylate,2-Deoxy-D-Glucose,Vecuronium Bromide, Ceftiofur Hcl,Ceftiofur Sodium,Buflomedil Hcl,Oteracil Potassium,Gimeracil,Cinildipine

主要产品有：异环磷酰胺、异环磷酰胺酰化物、2-脱氧-D-葡萄糖、维库溴铵、头孢噻呋、头孢噻呋钠、氧嗪酸钾、吉莫斯特、西尼地平、马尼地平、培美曲塞、培美曲塞酸、培美曲塞二钠、尼索地平、消旋卡多曲、雷尼酸锶、盐酸丁咯地尔、1-(3-三氟甲基苯基)哌嗪、4-溴-2-甲基苯甲酸。

Main products: Ifosfamide,Ifosfamide acylate,2-Deoxy-D-Glucose,Vecuronium Bromide, Ceftiofur Hcl,Ceftiofur Sodium,Buflomedil Hcl,Oteracil Potassium,Gimeracil,Cinildipine, Manidipine dihydrochloride,Pemetrexed intermediate,Pemetrexed acid,Pemetrexed Disodium, Nisoldipine, Racecadotril, Strontium Ranelate, 1-(3-Trifluoromethylphenyl)piperazine hydrochloride, 4-Bromo-2-methylbenzoic acid.

主营业务：主要产品有：异环磷酰胺、异环磷酰胺酰化物、2-脱氧-D-葡萄糖、维库溴铵、盐酸头孢噻呋、头孢噻呋钠、氧嗪酸钾、吉莫斯特、西尼地平、盐酸马尼地平、培美曲塞、培美曲塞酸、培美曲塞二钠、尼索地平、消旋卡多曲、雷尼酸锶、盐酸丁咯地尔、1-(3-三氟甲基苯基)哌嗪盐酸盐、4-溴-2-甲基苯甲酸。

The condensation reaction,in which the yield of intermediate product after refining process was more than 90%,used iso-butylaldehyde and formaldehyde as materials,Et 3N as catalyst.The hydrogenation,in which the conversion of hydroxypivaldehyde and selectivity of NPG were respectively 99% and 95%,used Cu-ZnO as catalyst,and ethanol as solute,meanwhile in the hydrogenation,the impurity in material could also ...

缩合反应采用异丁醛和甲醛为原料，三乙胺为催化剂，在 60℃左右反应，缩合产物经减压蒸馏和结晶、干燥，得到收率为 90 %以上的中间体羟基戊醛；加氢反应采用自制的Cu -ZnO催化剂，乙醇为溶剂，在 15 0℃将HPA加氢生成新戊二醇，HPA转化率为 99%，新戊二醇收率在 95 %以上，而且HPA缩合反应的副产物在加氢反应中也转化为新戊二醇。

Three methods are used to prepare molecular imprinted polymers,which include conventional bulk technique or polymerization with ultraviolet initiated in low temperature and polymerization with silica-gel as sacrificial materials. In the polymerization procedure , Sulfamethazine(SM2)and Sulfisoxazole were used as target template molecules, methacrylic acid and 4-vinylpyridine(4-VP) and acrylamide were selected as functional monomers, ethylene glycol dimethacrylate as crosslinker, azobisisobutyronitrile was used as initator.

主要工作如下：首先，以磺胺异噁唑和磺胺二甲嘧啶为模板，分别以4-乙烯基吡啶，甲基丙烯酸，丙烯酰胺为功能单体，以二甲基丙烯酸乙二醇酯为交联剂，偶氮二异丁腈为引发剂，采用了传统方法(60℃恒温水浴)、牺牲硅胶法及低温紫外光聚合法等三种方法合成了一系列的磺胺类药物印迹聚合物。

Project Background and Conditions: The company started research new chemical products in 1998. After two years of efforts, a series of pharmaceutical intermediate sulfathiazole leave instructions, including : 3- methyl sulfathiazole leave instructions, 2- sulfathiazole leave instructions ethanoic acid, 2- acetyl sulfathiazole leave instructions, 2-thiofuran amino ethane ,2-thiofuran acetic, 3,4,5- tighter nitrobenzene have been successfully developed. 2-thiofuran amino ethane are the precursors raw materials of series antibiotic analgesic.

二、项目建设背景及条件：1998年公司开始研究开发高新精细化工产品，经过两年的努力，已成功研制出噻吩系列医药中间体，包括：3-甲基噻吩、2-噻吩乙酸、2-乙酰噻吩、2-噻吩乙胺、2-噻吩乙醇、3，4，5-三氯硝基苯等。2-噻吩乙胺系列噻吩产品使用于血小板及血栓有关的心脏血管病及消炎镇痛等如氯吡格雷、兴孢噻吩钠、兴孢西丁、噻吩洛酸等十几种新药的前体原料，是国家政策鼓励发展和有自主知识产权的项目。

The catalytic system composed of NHPI and transition metal ion can catalyze effectively ethane into acetic acid,cyclane into dicarboxylic acid,toluene into benzoic acid,alkene into epoxide,alkyne into acetylenic ketone,and amide into imide;NHPI used alone can catalyze adamantane to be carbonylated,hydrogen peroxide prepared by oxidization alcohol;NHPI combined with as...

NHPI与过渡金属离子组成的催化体系能高效地催化乙烷氧化为乙酸、环烷烃氧化为二元羧酸、甲苯氧化为苯甲酸、烯烃氧化为环氧化物、炔烃氧化为炔酮、酰胺氧化为酰亚胺；NHPI单独使用能催化金刚烷发生氧化羰基化反应、催化氧化醇制取过氧化氢；NHPI与有机助催化剂如偶氮二异丁腈、溴化季铵盐、蒽醌和醇等也能催化分子氧氧化反应。

Two kinds of ashless and non-phosphorus additives, hydroxyl-containing dithiocarbamate derivatives were prepared.

合成了2-乙羟基-吗啡啉二硫代氨基甲酸酯和2-乙羟基-二正丁胺基二硫代氨基甲酸酯两种添加剂。

Studing on samarium diiodide promoted asymmetric intramolecular reducing coupling reactions, we have made the resolution of the racemic biaryl dials by using enantiomeric N-tert-butanesulfinamine as the resolving reagent successfully and thus obtained a series of axially chiral biaryl dials with high enantiomeric excess.

中文摘要在二碘化钐促进的分子内不对称还原偶联反应中，我们不仅对联芳基二醛底物的合成路线进行了优化，还发现N-叔丁基亚磺酰胺辅基可以作为手性试剂，成功地对联芳基骨架二醛化合物进行拆分，得到高对映体过量的轴手性二醛类化合物。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。