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The present invention relates to a coating composition comprising; A at least one polyester oligomer prepared from reactants comprising a 20 60 wt.% of at least one polyol, b 5 30 wt.% of at least one polycarboxylic acid selected from the group of cyclic polycarboxylic acids, the esters or the anhydrides thereof, wherein the carboxyl groups are separated by 3 carbon atoms or less, and from the group of alpha , beta -saturated acyclic polycarboxylic acids, the esters or the anhydrides thereof, and c 20 60 wt % of at least one monocarboxylic acid, the sum of the wt.% indicated for the reactants,, and always being 100 wt.%, and the oligomer being a low-viscosity oligomer having a weight average molecular weight Mw of less than 5,000, and a hydroxyl number in the range of about 200 to about 400 mg KOH/g oligomer, and B at least one polyisocyanate.

本发明涉及一种包含如下组分的涂料组合物:A至少一种由包含如下成分的反应物制备的聚酯低聚物:a20-60wt%至少一种多元醇,b5-30wt%至少一种选自其中羧基被3个或更少碳原子隔开的环状多元羧酸、其酯或酸酐以及选自α,β-饱和的无环多元羧酸、其酯或酸酐的多元羧酸,以及c20-60wt%至少一种一元羧酸,其中反应物、和的wt%之和总是为100wt%,所述低聚物是重均分子量Mw低于5000且羟基值为约200-约400mg KOH/g低聚物的低粘度低聚物,以及B至少一种多异氰酸酯。

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In the protein of scolopendra, scorpio, pheretima,the content of Glycine, Alanine, Valine,Tyrosine,Phenylalanine and Arginie is higher,but the content of glutaminic acid is significantly lower than the daily animal and plant albumens.

探讨结果如下:一、氨基酸分布与蜈蚣、全蝎、地龙药理作用的关系在蜈蚣、全蝎、地龙三种天然动物药材中甘氨酸、丙氨酸、酪氨酸、苯丙氨酸、精氨酸含量高,谷氨酸含量则显著低于常见动植物蛋白。

In the preparation method, zirconium is mixed with benzenephosphonic acid according to the molar ratio of 1:2 to 1:4, and Alpha-zirconium phenyl phosphonate is produced by centrifugal washing after one to five days of crystallization under the temperature of 50 DEG C to 100 DEG C; deionized water is added in order to prepare Alpha-zirconium serosity, the solid content of which is 4 percent to 8 percent; the Alpha-zirconium serosity is granulated and dried by a rotary spray dryer, the feeding speed of the Alpha-zirconium serosity imported into an atomizer is controlled between 20ml/min and 80ml/min, and the temperature of a hot air inlet is controlled between 120 DEG C and 200 DEG C.

本发明涉及一种大比孔容微球α-苯膦酸锆及其制备方法,其颗粒尺寸为10~100μm,比孔容为0.908cc/g,比表面积为125.8m 2 /g;其制备方法是将锆和苯膦酸以摩尔比1∶2~1∶4混合,在50~100℃温度条件下晶化1~5天,离心洗涤得到α-苯膦酸锆;加入去离子水配制α-苯膦酸锆浆液,其固含量为4-8%;将α-苯膦酸锆浆液用旋转式喷雾干燥器进行造粒、干燥,控制α-苯膦酸锆浆液输入雾化器的进料速度为20~80ml/min,控制热风进风口温度为120~200℃;该方法具有操作简单、合成条件温和,对环境污染小等特点,该材料应用于催化、催化剂载体、吸附、离子交换等方面。

It has offered the information of the boiling points of the chemical compounds, and it is helpful to reutilize them after their separation by rectification. The results showed that the main compounds of the heavy cut of terpineol were longifolene and βcaryophyllene. They are from the raw material, terpinene oil.

松油醇的合成工艺方法主要有两种:一种是一步法,即松节油在酸催化作用下直接进行水合反应生成松油醇;另一种是二步法,即松节油首先在酸催化作用下水合成萜二醇,再经稀酸催化脱水生产松油醇。

A chromium free conversion coating at least equivalent in corrosion protective quality to conventional chromate conversion coatings can be formed on metals, particularly cold rolled steel, by a dry-in-place aqueous acidic liquid comprising: a component of anions, each of said anions consisting of at least four fluorine atoms and at least one atom of an element selected from the group consisting of titanium, zirconium, hafnium, silicon, and boron, and, optionally, ionizable hydrogen atoms, and optionally, one or more oxygen atoms; a component of cations of elements selected from the group consisting of cobalt, magnesium, manganese, zinc, nickel, tin, zirconium, iron, and copper; the ratio of the total number of cations of this component to the total number of anions of component being at least 1:5; sufficient free acid to give the composition a pH in the range from 0.5 to 5.0; a component selected from the group consisting of phosphorus-containing inorganic oxyanions and phosphonate anions; and a component selected from the group consisting of water-soluble and water-dispersible organic polymers and polymer-forming resins and, preferably, also including a component selected from the group consisting of tungstate, molybdate, silicotungstate, and silicomolybdate anions.

通过对包含以下成分的含水酸性液体进行干燥,可以在金属上形成无铬的转换涂层,该涂层与普通铬酸盐转换涂层相比,至少在抗腐蚀质量上等效:$_一种阴离子成分,所述各个阴离子包括至少4个氟原子,至少选自钛、锆、铪、硅与硼元素中的1个原子。任选地可离解的氢原子,任选地1个或多个氧原子;$_一种选自钴、镁、锰、锌、镍、锡、锆、铁与铜元素的阳离子成分,上述成分的阳离子总数与成分内的阴离子总数之比至少为1∶5;$_足够的游离酸以使该组合物的pH值在0.5~5.0的范围内;$_一种选自含磷的无机含氧阴离子与膦酸盐阴离子的成分;$一种选自水溶性与水可分散性有机聚合物与聚合物形成的树脂的成分,优选还包括一种选自钨酸盐、钼酸盐、钨硅酸盐与钼硅酸盐阴离子的成分。

The invention uses the fermentation liquor of one Escherichia coli generating polysialic acid as material, filters and removes thallus, adds some solvents as sodium chloride and alcohol into supernatant to deposit polysialic acid, dissolves the polysialic acid deposits via deionized water, filters to remove modified protein, uses alkali prolease to treat filtrate, complexes deposits via cetyl pyridinium chloride or cetyltrimethylammonium bromide, and dissociates, uses over alcohol to deposit polysialic acid, dissolves the deposits via ultra-pure water, grades and purifies via chromatography column, collects and dialyzes eluent, cools and dries to obtain polysialic acid.

本发明以一株产聚唾液酸大肠杆菌的发酵液为原料,经过过滤去除菌体,上清液加入适量氯化钠和乙醇等溶剂沉淀出聚唾液酸,聚唾液酸沉淀用去离子水溶解,再用过滤去除变性蛋白质,滤液经过碱性蛋白酶处理、氯代十六烷基吡啶或十六烷基三甲基溴化铵络合沉淀并解离后,再用过量乙醇沉淀出聚唾液酸,聚唾液酸沉淀用超纯水溶解,用层析柱进行分级纯化,收集洗脱液经过透析,冷冻干燥得聚唾液酸产品。

Polyols can be divided into latex polyol and dispersion polyolaccording to the way of preparation. In this paper, acrylic latex polyol and acrylic dispersionpolyol were synthesized respectively. One kind waterborne polyisocyanate, which was waterbornehexamethylenediisocyanate trimer, was obtained by hydrophilic modification. Andisophorone diisocyanate trimer (T1890E), which can formulate into 2K-WPU coatings withpolyols, was selected from the unmodified polyisocyanates.

本文合成了两种羟基组分:丙烯酸乳胶多元醇和丙烯酸分散体多元醇,亲水改性得到了一种水性多异氰酸酯组分:水性六亚甲基二异氰酸酯三聚体,同时在未改性的多异氰酸酯组分中遴选了一种多异氰酸酯:异佛尔酮二异氰酸酯三聚体(T1890E),可用来组成双组分水性聚氨酯涂料。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。

Bitter medicinal herbs are for the heart, acidic herbs for the lungs and bronchial tube, and salty ones for the kidneys. As soon as one tastes it, one can get a general idea of whether the medicine obtained is the correct one.

大略地说,味酸的治肝脏,风疾,味甜的治脾胃,郁闷等病,味苦的治心,味辛辣的治肺,气管诸疾,味咸的治肾;把药汁一尝,马上可以试验出医生的药方,或药房抓的药,有没有被搞错。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。