一溴化的

In the precence of the base catalyst KF/Al2O3, the one - pot reaction of 2 -hydroxybenzaldehyde or 2 - hydroxynaphthaldehyde with ethyl α- bromoacetate,α-bromoacetophenone , 1,4 - dichloromethylbenzene , 4,4'- dichloromethylbiphenyl and 1,5 -dichloromethylnaphthalene gave the benzofuran compounds in 38-89% yield.

本文报道用 KF/Al_2O_3作为碱催化剂，由水杨醛或2-羟基-1-萘醛分别和α-溴代乙酸酯、α-溴代苯乙酮、苄基氯、4，4'-二氯甲基联苯和1，5-二氯甲基萘等进行一锅化缩合反应，以38～89％的产率合成了14种芳并呋喃化合物。

A new type of difunctional initiator (benzyl dibromide, ethyl dibromoacetate) was proposed in this paper and used to synthesize poly based triblock copolymers such as PSt-PBA-PSt, PMMA-PBA-PMMA.

本论文提出一种新型ATRP双官能团引发剂(如α，α-二溴化苄、α，α-二溴乙酸乙酯)，并用聚合反应速度法、GPC法、核磁分析法进行双官能度的验证，并通过两步聚合合成以聚丙烯酸酯为中间嵌段、苯乙烯或甲基丙烯酸甲酯为两端嵌段的ABA型三嵌段共聚物。

The overall yield was 43.6%.The yield of reduce of ester was increased nearly one times than the past method because of KBH4-LiCl as the reducing agent instead of NaBH4. Changing the reaction conditions of bromization, the one-way yield enhanced 30%. The yield of reduce of the bromide was added by one times by improving the process. Tefluthrin was achieved by the catalytic esterification of DCC and DMAP.

优化后工艺对四氟对苯二甲酯的还原采用了廉价高效的还原试剂KBH4-LiCl，使收率比NaBH4法提高了近一倍；对溴化反应条件进行了优化，单程收率提高了30%；对溴化物还原条件的优化，使其收率提高了近一倍；采用了催化剂DCC和DMAP合成了最终产品七氟菊酯。

Based on the absorbance change of indicators with the concentration of hydrogen ion released from the enzyme-catalyzed reaction, a convenient colorimetry method is established for the assay of acidic phospholipase 〓 and glycogen phosphorylase b Brilliant yellow and bromothymol blue are chosen as indicators for assays of acidic phospholipase 〓 and glycogen phosphorylase b by following the absorbance changes at 495 nm and 615nm respectively The method is simple, sample-saving, sensitive and valid for a wide range of enzyme concentrations.

为了研究糖原磷酸化酶的激活动力学和酸性磷脂酶〓的复性过程，我们根据酶催化反应中释放氢离子浓度的变化引起相应的指示剂的光吸收发生变化的原理，建立了一种简捷的比色法，用于测定酸性磷脂酶〓和糖原磷酸化酶b的活性。选用亮黄和溴麝香草酚兰分别作为酸性磷脂酶〓和糖原磷酸化酶b测活的指示剂，在495 nm和615 nm处检测二者的光吸收值的变化，可以测定酶活。本方法的优点是，可在比较宽的酶浓度范围内进行活力测定，而且操作简单、节省样品、灵敏度高。

The chapter two was focused on the samarium diiodide promoted organic reactions and their applications in organic synthesis, firstly, a new synthesis of highly substituted cyclopentadienes from a,β-alkynone promoted by samarium diiodide was investigated and the highly substituted cyclopentadienes were prepared in moderate to good yields under mild conditions. Secondly, the Michael addition and Michael-aldol tandem reaction of diorganyl diselenides or diorganyl disulfides with α,β-alkynones mediated by samarium diiodide were studied and a series of alkenylsulfides and alkenylselenides were prepared in good yields. Then the highly regioselecfive nucleophilic addition of the allylsamarium bromide to α,β-alkynones were explored. We found that the allylsamarium bromide reacts with α,β-alkynones to afford regiospecificly 1. 2-nucleophilic addition products in good yields under mild condition. At last we studied the coupling reaction of aryl halides promoted by NiCl〓/PPh〓/Sm〓.

第二章 研究了二碘化钐、金属钐促进的有机反应：1、二碘化钐促进下α，β-炔基酮的偶联环化反应，提供了一种制备多取代环戊二烯的新方法；2、二碘化钐促进下的二硫醚、二硒醚与α，β-炔基酮的Michael加成反应，为高产率地制备多取代的烯基硫或烯基硒化合物提供了方便可靠的新方法；3、二碘化钐促进下的二硫醚、二硒醚与α，β-炔基酮和醛、酮的Michael—aldol串联反应，提供了一种一锅法高产率地制备多取代的含硫的烯丙基醇或含硒的烯丙基醇类化合物的方便可靠的原子经济性的新方法；4、烯丙基溴化钐与α，β-炔基酮的高度区域选择性的1，2-亲核加成反应；5、NiCl〓/PPh〓/Sm〓促进的卤代芳烃的偶联反应-一种从各种卤代芳烃制备联苯类化合物的有效方法。

A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.

本发明涉及一种制备对氟－2－(2－甲基－3－氧丙基)－4－氧－N，3－二苯基－苯丁酰胺(1)的方法，其包括以下步骤：新制的苯乙酰氯与氟苯在AlCl3催化下进行Friedle－Craft酰化反应，得到对4－氟－苯基苄基酮(4)；化合物(4)在少量AlCl3催化下进行羰基α位溴化，得到α－溴－4－氟－苯基苄基酮(5)；然后(3)异丁酰乙酰苯胺在乙醇钠作用下与化合物(5)进行缩合。

The following conclusions have been gotten from a large amount of experiments and determinations: Triiodide, pentaiodide, heptaiodide, nonaiodide, undecaiodide of solid tetra-n-butyl ammonium polyiodides and tetrabutyl ammonium bromide polyiodides can be synthesized by solid phase process which is a economic easy way, while its not suitable for synthesizing solid tetramethyl ammonium polyiodides; Solution polyiodides of triiodide, pentaiodide can be synthesized through the complexation process, and TX-10 is a better complexing agent; Triiodide, pentaiodide, heptaiodide resinic polyiodides were synthesized by ion-exchange of resinifying process, and that is a viable easy way.

在大量实验和分析的基础上，可得到以下结论：用固相法可以合成出碘三、碘五、碘七、碘九和碘十一形式的正四丁基多碘化铵固体高聚碘和四丁基多碘化溴化铵固体高聚碘系列化合物，是制备高聚碘的经济、方便的合成方法，但此法对合成四甲基多碘化铵固体高聚碘系列化合物并不适用；TX-10是合成溶液高聚碘较佳的络合剂，通过其络合作用可以合成出碘三和碘五形式的溶液高聚碘；采用树脂法，通过离子交换，合成出了碘三、碘五和碘七形式的树脂高聚碘，此法简单可行。

A novel method for synthesizing a series of tribromomethylarenes by halogen exchanging of trichloromethylarenes with boron tribromide was reported.

报道了一种以三氯甲基芳烃与三溴化硼反应制备系列三溴甲基芳烃的新方法。

On the base of the results, a new synthetic route of brominated Q0 was reported. The method was more favorable for the preparation of Q0, and the yield was above 86%.

在此基础上，研究了溴化Q0的合成方法，形成了一条新的、简便的溴化Q0的合成路线，收率达86%以上。

The current knowledge concerning effects of polybrominated diphenyl ether on benthic aquatic organisms is still very limited although they have been widely used as fire retardant additives for 3 decades.

多溴联苯醚(polybrominated diphenyl ether，PBDEs)为溴化阻燃剂的一种，近30年来已被广泛地运用，但目前仍少有研究探讨其对水生底栖生物之毒性影响。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。