一天的工作

Methods The experimental arrhythmia models were induced with barium chloride (BaCl2),uabaina and aconitine in rats and cobayaes.The incidence rate and mortality rate of arrhythmia,the emergence time and the duration of arrhythmia induced with BaCl2 were recorded in rats pretreated with CASI (in dosages of 25,50, and 100 mg·kg-1 sublingual vein injection).At the same time,the dosages of uabaina and aconitine were observed when the ventricular premature contraction,ventricular tachycardia,ventricular fibrillation and cardiac asystole were appeard in rats and cobayaes pretreated with CASI (in dosages of 25,50, and 100 mg·kg-1 sublingual vein injection).

制备氯化钡(BaCl2)、哇巴因及乌头碱诱导的大鼠及豚鼠实验性心律失常模型，CASI按25、50、100 mg·kg-1分为3个剂量组，舌下静脉给药1次，不给CASI作为对照组，记录大鼠给BaCl2后心律失常的发生率、出现时间、持续时间及动物的死亡率；观察豚鼠及大鼠出现室性早搏、室性心动过速、心室颤动及心脏停搏时哇巴因及乌头碱的用量。

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这样，在二线市场就相对拉开了&空挡&，为后来者的发展留出了足够的空间。