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We study the phase-separation and microstructure of the pure binary and trinary mixed LB and LS films of Dimyristoyl phosphatidyicholine cholesteroland sphingomylin deposited from pure water subphase by π-A isotherms and tapping mode Atomic Force Microscopy.

在本章中我们用这种极易溶于水的阳离子型聚合物PEI为一软垫,研究以此软垫为基底的不同生物分子和它们不同种二元及三元混合单分子膜体系在含PEI亚相上的相结构情况,初步的讨论了它们以云母为基底的IS膜和LB膜的微结构或者说是该软垫对单分子膜微结构的影响。

As a new molecular cytological method, it has widely been used in cellular genetics and molecular biology.

作为一种新型的细胞分子遗传学技术,目前已广泛应用于细胞遗传学、分子生物学等领域。

Results EY-TF was a dialyzable substance (pH6.9±0.5) with a relative molecular weight of less than 12000, containing 18 kinds of amino acids. The polypeptide and ribose contents of EY-TF were 1.2mg/ml and 152.94μg/ml respectively. The EY-TF was negative in protein reaction test and showed the maximum ultraviolet absorption at 270nm.

结果 EY-TF是一种可透析、含有18种氨基酸、相对分子质量小于12000的小分子物质,其多肽含量为1.2mg/ml,核糖含量为152.94μg/ml,pH6.9±0.5,蛋白反应阴性,最大紫外吸收光谱在270nm处。

Nitric oxide is highly diffusible and with very low solubility aqueous solutions, which could function as an intracellular and intercellular signaling molecule.

一氧化氮(Nitric Oxide,简称NO)是一类脂溶性的可扩散小分子物质,可以作为细胞间或胞内信号分子。

It was found that the transition from coil to helix was completed in the concentrated solution ofiPS/octadecyl benzoate system which has never been reported before.

在一般的短链分子溶剂中,只有在温度降至很低,等规聚苯乙烯的分子链才有可能部分规整排列。

Many cocrystal of pyrrolic amide with solvent molecules are also obtained which means pyrrolic amide is a new receptor for neural or anionic species.

我们还得到了许多吡咯酰胺化合物与溶剂分子络合的晶体结构,这说明吡咯酰胺化合物可以作为一种分子识别主体。

In the area of selective catalysis, they will soon publish the first examples of stereochemically thoroughly investigated Enantioselective Organo-Autocatalysis, a process that demonstrates conceptually new catalysis design strategy and also provides structurally well-defined small-molecule models that may help explain the origin and maintenance of homochirality fundamental to the functions of biological systems.

在相邻的选择性催化领域,他们即将发表设计发现的首例有机小分子催化的高立体选择性自复制过程(Enantioselective Organo-Autocatalysis),此类反应不仅避免了繁琐的催化剂和产物分离问题,更有意义的是充分利用了产物自身的催化功能,并为分子手性单一性这一生命体根本特征的起源和自发维持提供了第一个简洁的小分子模型系统。

Through cyclic hydrogen bonding with motif formed by coordinated water molecules and coordinated hydroxyl groups of dhbd from adjacent tetranuclear units, these adjacent neighbors are connected to afford a 1D supramolecular chain along axis a, which is further extended via aromatic intercalations and other crystallization water molecules into a 3D structure with channels.

毗邻的四核单元通过配位H2O分子和配位羟基O原子形成的 R 22(8)型环形氢键桥的连接,沿a轴方向构建了四核单元交替相连的一维超分子链;链间籍苯环的π-π堆积作用和晶格水分子氢键链的连接进一步扩展为具有隧道的三维结构。

The research indicated that, the structure inside the pure C8TES SAM was indeed loose and unassembled completely, the molecule density inside the SAM was very low, which would result in an ultra-low surface contact angle, only 20~21°, on the C8TES SAM surface.

我们的研究表明,由于C8TES分子头部三个乙氧基形成的空间(来源:b5e5ABe3C论文网www.abclunwen.com)位阻的影响,C8TESSAM的内部处于一种不完全组装的松散状态,所形成的自组装单分子膜内分子密度偏低,造成C8TES SAM的表面接触角偏低,只有20~21°。

A one-step method for the synthesis of aromatic indolizine derivatives byintramolecular 1,5-dipolar cyclization reaction of 2-(2-arylethenyl)pyridinium N-ylidesin the presence of an oxidant has been studied for the first time. In the presence ofelectron-deficient olefins, however, 2-(2-phenylethenyl)pyridinium N-ylides underwent1,3-dipolar cycloadditions and then aromatized in situ by TPCD to produce indolizinederivatives, indicating 1,3-dipolar cycloaddition proceed more readily than 1 ,5-dipolarcyclization in these conditions. Pyridinium disubstituted N-ylides, readily obtainedfrom corresponding pridinium and β-chlorovinyl ketone, underwent thermalintramolecular 1,5-dipolar cyclization to give indolizine derivatives easily.Indolizinecarbaldehyde derivatives were synthesized starting from 2-pyridinecarbaldehyde in four-steps involving 1,3-dipolar cycloaddition reaction.

本文首次研究了2-(2-芳基乙烯基)吡啶N-叶立德在氧化剂存在下的分子内1,5-偶极环化反应,采用一锅法合成了中氮茚衍生物;研究了这些N-叶立德的1,5-偶极环化和1,3-偶极环加成反应的选择性,发现当有缺电子烯烃存在时,优先进行1,3-偶极环加成反应,而不再发生分子内1,5-偶极环化反应;由β-氯乙烯酮方便地得到了烯丙基N-叶立德,他们在加热时进行分子内1,5-偶极环化反应而得到中氮茚衍生物;由2-吡啶甲醛为起始原料,通过1,3-偶极环加成反应等四步反应,得到了重要的中氮茚甲醛衍生物,这些反应都具有条件温和和操作简便的特点,是合成中氮茚衍生物的新方法。

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