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Firstly, 3-ethylthiobutanal was prepared from crotonaldehyde reacting with ethanehiol in triethylamine with high yield. Secondly, methyl acetoacetate was converted to 6-ethylthiohept-3-en-2-one by three steps via hydrolysis, condensation with 3-ethyltio-butanal and dehydration, then 6-ethylthiohept-3-en-2-one was cycloco ndensed with dimethyl malonate by Michael addition and Claisen condensation, followed by saponification and decarboxylation to give the intermediate of 5-(2-ethylthiopropyl)-cyclohexane-1,3-dione.

首先,以巴豆醛与乙硫醇为原料,在三乙胺的催化作用下高收率制得3-乙硫基丁醛;然后从乙酰乙酸甲酯出发,通过碱水解、与3-乙硫基丁醛缩合、脱水三步反应合成6-乙硫基-3-烯-2-庚酮,接着6-乙硫基-3-烯-2-庚酮与丙二酸二甲酯通过Michael加成和Claisen缩合成环,再通过皂化和脱羧反应生成中间体5-[2-丙基]-1,3-环己二酮;再与丙酸酐反应丙酰化,最后与0-3-氯-2-丙烯基羟胺肟化,得到目标化合物烯草酮。

Stem cell research might yield ways to grow new body parts, but without a parallel curer for Alzheimer's, this wonderful new technology would do no more than allow more people to persist in vegetative states for years longer than is currently possible.

干细胞研究可能会找到新器官的培育途径,但是如果我们没有同时找到医治老年痴呆症的良方,这种奇妙的新技术无非只是让更多的人在植物状态下苟活更长的时间罢了。

Stem cell research might yield ways to grow new body parts, but without a parallel curer for Alzheimer's, this wonderful new technology would do no more than allow more people to persist in vegetative states for years longer than is currently possible.

干细胞研究可能会找到新器官的培育途径,但是如果我们没有同时找到医治老年痴呆症的良方,这种奇妙的新技术无非只是让更多的人在植物状态下茍活更长的时间罢了。

In order to mimic this repair process of apoenzyme, we synthesized two model compounds, in which tryptophan and/or tyrosine was covalently linked to cyclobutane thymine dimer, and measured the splitting quantum yield of dimer under 295 nm light. By investigating the photosensitized splitting properties of the dimer, some new insights into the intramolecular electron-transfer process were gained.

为了模拟酶蛋白的这一修复过程,合成了色氨酸和/或酪氨酸与胸腺嘧啶二聚体共价连接的化合物,作为酶-底物复合物的模型,研究了它们在295 nm光照射下氨基酸残基光敏化二聚体裂解的性质,测定了二聚体裂解量子产率,获得一些新的结果并对其进行了分析。

This desaturase, when expressed in Escherichia coli, desaturated stearic acid to yield oleic acid, but did not desaturate other fatty acids in E. coli. These results indicate that PvFadA is specific to stearic acid.

通过将PvfadA基因在大肠杆菌表达系统中成功表达,PvFadA可以特异性地将C18:0脂肪酸转变成C18:1脂肪酸。

For more upgrade aluminium oxide yield, optimize indices, energy conservation and save cost, it is necessity to desilicify steps reconstruction.In order to overcome the shortcoming of the desilication used in Shangdong Alumina Corpotation,three technology such as indirect heating, continious desilication,deep desilication by separation of the sodium-silicon residue.

本文通过对理论界关于烧结法生产氧化铝脱硅原理的研究,结合国内主要氧化铝生产厂家脱硅实践方面的经验,针对山东铝业公司烧结法氧化铝生产脱硅工序的现状,运用间接加热连续脱硅、钠硅渣分离深度脱硅和HCAC法高效脱硅三项科研成果,对原有的三次脱硅工艺改为二次脱硅工艺。

Based on this result, a new technology is suggested, that is by regulating the effective sulphonating contents of 1-amino-anthraquinone, adjusting the concentration of sulfuric acid to hydrolyze 1-amino-anthraquinone disulfonic acid conversing to 1-amino-anthraquinone -2-sulfonic acid, and briminating the hydrolyzed product in 100% sulfuric acid, 87% yield of Bromamino-acid was achieved, 10% higher than the conventional method prepared by "oleum method".

此新工艺,溴氨酸在产物中含量可达87%,比常规的发烟硫酸法生产溴氨酸提高了10%,质量和收率都接近或达到溶剂法生产的水平。 1,5-二硝基蒽醌和1,8-二硝基蒽醌是生产分散蓝56、分散蓝73等一系列分散染料重要中间体。

Water was used to elute foreign matter, and then 30% ethanol was used to elute SPC, whose content was 96.01% and the yield was 3.76%.

黑龙江产高粱原花青素的分离鉴定和结构表征 2.1 SPC的初步结构分析采用UV、IR、MS等现代分析技术对SPC进行了初步结构分析。

To improve the selectivity, the Co/Mn/Br catalyst system with ethanal as an additive was studied and the reaction conditions were also optimized, which were as follows:the amount of ethanal 10%(mole ration base on the substrate), reaction temperature 100℃,reaction time 30min,the oxygen pressure 0.2MPa, the amount of the composite catalyst Co/Mn/Br 7%,the mass ration of different ingredients 2:2:1. Under these conditions, the yield comes to 24.10% and the selectivity reaches 75.03%.

为了提高反应的选择性,论文初步研究了以乙醛作为添加剂条件下各工艺参数的影响,并进行正交优化,得出最佳条件为:乙醛加入量1:10,反应温度100℃,反应时间30min,氧气压力0.2MPa, Co/Mn/Br混合催化剂加入量7%,质量比2:2:1,在此条件下,反应产率为24.10%,选择性可达75.03%。

Combinatorial chemistry is a type of synthetic strategy which systematically connects a set of"building blocks"such as amino acids, nucleotide and small organic molecules to yield a large array of diverse molecular entities described as a combinatorial library. It also refers to the process of screening the compounds with the expective activity from the library.

组合化学是将诸如氨基酸、核苷酸、有机小分子等构建单元按某种组合方式连接起来,合成出包含大量化合物的化学库,并从中筛选出具有某种物理、化学或药理活性化合物的一套合成策略和筛选方案。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。