查询词典 xenobiotic

The result indicated BaP and the subsequent oxidative stress disturbed the expression of mitochondrion-encoded genes, and this was potential biomarker for oxidative stress following xenobiotic exposure.

研究表明，土壤中苯并［a］芘污染改变了蚯蚓线粒体基因组的表达水平，线粒体基因组表达异常是多环芳烃污染胁迫的重要分子生物标记物。

The Division of Neurology is primarily dedicated to teaching and research in neurology including molecular aspects of xenobiotic enzymes, epilepsy, percutaneous carotid and vertebral artery angioplasty, In vitro and in vivo experimental studies on neuroprotective effects of neuropeptides during focal cerebral ischaemia, cardiovascular and autonomic complications during the acute stage of stroke.

神经学分部主要致力于神经学的教学与研究，其研究领域包括异生化合酶类的分子相，癫痫，颈动脉和脊椎动脉血管成形术，脑局部缺血中神经肽的体内和体外神经保护，急性中风时的心脏血管和自发的并发症等。

It is reported that COX-2 plays important roles in it, through xenobiotic metabolism, inhibiting apoptosis, development of inflammation-stimulated hyperplasia and metaplasia, suppressing host immune responses, inducing angiogenesis and promoting infiltration and metastasis.

食管癌具有高发病率和死亡率，近年来认为环氧合酶-2通过异型生物质代谢，抑制凋亡，参与慢性炎症、免疫抑制，上调血管生成因子的表达，以及促进肿瘤的浸润和转移在其致癌中起重要作用。

It is unavoidable for body to exposure of organic anions including endogenous agents such as hormones, neurotransmitters and cellular metabolites, and xenobiotic agents such as medication, herbicides, pesticides, and plant and animal toxins.

机体接触各种潜在毒性有机阴离子，包括内源性物质如激素、神经递质和细胞代谢产物；外源性化学物质如多种药物、农药和动植物毒素等。

While the efficiency of generating cells that exhibit most hepatocyte characteristics is high, we noted that the repertoire of mRNAs encoding phase I and phase II enzymes, which have important roles in controlling drug metabolism and xenobiotic responses, is incomplete when compared with cadaveric livers.

尽管我们能够高效培养出具有大部分肝细胞特征的细胞，但通过与尸体肝脏进行比较发现，我们所培养出的 mRNA编码的 I 相和 II 相酶并不完全，而这些酶在控制药物代谢和外源化合物反应方面发挥着重要作用。

In conclusion, species-specific responses of hepatocytes to cytokines and interactions with xenobiotic metabolites may limit the clinical effectieness of porcine hepatocytes in BAL.

结论，肝细胞之间对细胞因子的物种特异性反应及对异源性代谢产物的相互作用可能限制了猪肝细胞作为生物人工肝在临床的应用效果。版权声明：本译文文字内容归丁香园网站（http：//www.dxy.cn）所有，未经网站书面许可，请勿转载或摘编。

The superfamily of UDP-glucuronosyltransferase catalyze glucuronidation reaction, the most important process that increase substrate solubility in water and aids in their excretion by addition of sugars to fat-soluble chemicals both drugs and other xenobiotic carcinogens.

UDP-glucuronosyltransferase superfamily这个家族的酵素可将内生与外生性的脂溶性化合物进行葡萄糖醛酸化，增加其水溶性，以便排出体外。UGT1A7与UGT1A10一般被认为於呼吸消化道中表现。

Patients with mild or moderate hepatic failure or intestinal fat-malabsorption syndromes, as well as patients who are taking anticonulsant medications, glucocorticoids, or other drugs that actiate steroid and xenobiotic receptor, require higher doses of itamin D (Table 3).7,88 Exposure to sunlight or ultraiolet B radiation from a tanning bed or other ultraiolet B–emitting deice is also effectie.

有几类病人需要更高剂量的维生素D（表3）[7，88]，如轻中度肝功能不全、肠脂肪吸收不良综合征的病人，服用抗惊厥类、糖皮质激素类以及可激活类固醇和异生质受体类药物的病人。病人通过适当的日光照射、躺在晒黑床上紫外线B照射或其他紫外线B放射仪治疗，也能取得增加维生素D用量的效果。

The effects of phenolic acid compounds in vegetables and fruits on metabolicactivation of BaP in rats,as well as 〓 and TCA induced lipid peroxidation inmouse and Salmonella typhimurium TA104 cells were investigated using DNAadducts as a biomarker to assess DNA damage induced by xenobiotic carcinogens.BaP was used to study the genotoxic carcinogenesis,while 〓 and TCA were usedto study the non-genotoxic carcinogenesis.The possible protection mechanisms ofphenolic acid compounds on DNA damage were studied.

本研究根据化学致癌过程的遗传毒性和非遗传毒性机理，以DNA加合物作为机体接触外来化学物而导致DNA损伤的生物学标志物，通过观察酚酸类化合物对大鼠体内BaP活化代谢以及〓和TCA诱导小鼠肝微粒体脂质过氧化的影响，及酚酸类化合物对BaP和TCA诱导的沙门氏菌TA100和TA104形成DNA加合物的影响，探讨蔬菜、水果中酚酸类化合物对外来化学物诱导的DNA损伤的保护机制。

Using semi-quantitative PCR within the exponential phase, with beta-actin as an external control, the constitutive transcriptional expression of genes of phase I (CYP1A), phase II xenobiotic metabolizing enzymes, HSP70 and ATP1A1 were also investigated.

应用半定量RT-PCR的方法，以β-肌动蛋白作为外参照，在指数期增长范围内分别得到了CYP1A、GSTA、GSTR、HSP70和ATP1A1 mRNA与β-肌动蛋白mRNA的比值，确定黄斑篮子鱼肝脏去毒相关基因的组成型表达水平。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。